Introduction: Nephroblastoma is a malignant embryonic tumor developed from metanephrogenic blastema. Its treatment is multidisciplinary. The objective of our work is to study the histoprognostic factors of nephroblastoma at the regional hospital of Thiès. Materials and Methods: This is a retrospective, cross-sectional and descriptive study of nephroblastoma over a period of 20 months, from September 22, 2022, to April 30, 2024. It was conducted in the pathological anatomy and cytology laboratory of Thiès Regional Hospital Center. Were included all children in whom nephroblastoma diagnosis was made on clinic and radiological evidence, which was confirmed by histological examination. Results: In total, 38 patients were eventually involved. The average age was 47 months with a female predominance. The circumstances of discovery were the abdominal mass present in 97% of cases. Thirty-seven (37) unilateral total nephrectomy specimens were recorded, with one case of bilateral nephroblastoma. The tumor predominated in the left kidney in 68 % of cases. The average tumor size was 14 cm. Regressive and mixed type nephroblastomas were the most represented cases, with 25.6% each. Intermediate risk was the most common factor, with 33 cases. Stage II was the most represented stage, and involved 17 nephrectomy specimens. Conclusion: The treatment of nephroblastoma in Thiès is multidisciplinary. It is a cancer that remains of late discovery in our context.
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