Acute generalized peritonitis complicating colonic perforation due to Mpox infection is a rare complication not reported to our knowledge. Clinical features include generalized rashes, infectious signs, and a distended painful abdomen. Management is medical-surgical. We report a case of a 38-year-old patient transferred to CTM/RD Congo for management of an acute surgical abdomen complicating Mpox Infection. Clinical examination on admission noted: fever, peritoneal facies, skin eruptions of different ages, ulcerated and necrotic crusts, and a distended and diffusely painful abdomen. An exploratory laparotomy revealed sigmoidal perforations. Perforated colitis, probably Mpoxic was selected as the cause of the acute generalized peritonitis.
References
[1]
Ross, J.T., Matthay, M.A. and Harris, H.W. (2018) Secondary Peritonitis: Principles of Diagnosis and Intervention. British Medical Journal, 18, k1407. https://doi.org/10.1136/bmj.k1407
[2]
Bassetti, M., Eckmann, C., Giacobbe, D.R., Sartelli, M. and Montravers, P. (2019) Post-Operative Abdominal Infections: Epidemiology, Operational Definitions, and Outcomes. Intensive Care Medicine, 46, 163-172. https://doi.org/10.1007/s00134-019-05841-5
[3]
Second meeting of the WHO International Health Regulations (2005) (IHR) Emergency Committee Concerning the Monkeypox Epidemic in Several Countries. https://www.who.int/news/item/23-07-2022-second-meeting-of-the-international-health-regulations-(2005)-(ihr)-emergency-committee-regarding-the-multi-country-outbreak-of-monkeypox
[4]
Patel, A., Bilinska, J., Tam, J.C.H., Da Silva Fontoura, D., Mason, C.Y., Daunt, A., et al. (2022) Clinical Features and Novel Presentations of Human Monkeypox in a Central London Centre during the 2022 Outbreak: Descriptive Case Series. British Medical Journal, 378, e072410. https://doi.org/10.1136/bmj-2022-072410
[5]
Mitjà, O., Ogoina, D., Titanji, B.K., Galvan, C., Muyembe, J., Marks, M., et al. (2023) Monkeypox. The Lancet, 401, 60-74. https://doi.org/10.1016/s0140-6736(22)02075-x
[6]
Huang, Y., Mu, L. and Wang, W. (2022) Monkeypox: Epidemiology, Pathogenesis, Treatment and Prevention. Signal Transduction and Targeted Therapy, 7, Article 373. https://doi.org/10.1038/s41392-022-01215-4
[7]
Yinka-Ogunleye, A., Aruna, O., Dalhat, M., Ogoina, D., McCollum, A., Disu, Y., et al. (2019) Outbreak of Human Monkeypox in Nigeria in 2017-18: A Clinical and Epidemiological Report. The Lancet Infectious Diseases, 19, 872-879. https://doi.org/10.1016/s1473-3099(19)30294-4
[8]
Rao, A.K., Schrodt, C.A., Minhaj, F.S., Waltenburg, M.A., Cash-Goldwasser, S., Yu, Y., et al. (2023) Interim Clinical Treatment Considerations for Severe Manifestations of Mpox—United States, February 2023. MMWR. Morbidity and Mortality Weekly Report, 72, 232-243. https://doi.org/10.15585/mmwr.mm7209a4
[9]
Basler, C.F. (2017) Molecular Pathogenesis of Viral Hemorrhagic Fever. Seminars in Immunopathology, 39, 551-561. https://doi.org/10.1007/s00281-017-0637-x
[10]
Marietta, M., Coluccio, V. and Luppi, M. (2022) Monkeypox Outbreak: After COVID-19, Another Challenge for the Hemostatic System? Internal and Emergency Medicine, 17, 2179-2183. https://doi.org/10.1007/s11739-022-03112-8
[11]
Kambale, T.B., Ebola, H.S.E., Bolengwa, D.L., et al. (2024) Infections des Parties Molles de la Main en Republique Democratique du Congo. https://doi,org/10.5281/zenodo.12800442
