Observation on the Effectiveness of Shen-Shi Zhi-Tong Plaster Combined with Lei-Huo Moxibustion in the Prevention and Treatment of Chemotherapy-Induced Gastrointestinal Reactions

Objective: This study aims to explore the application effects of Shen-Shi Zhi-Tong plaster combined with Lei-Huo moxibustion in preventing and treating gastrointestinal reactions induced by chemotherapy, particularly its efficacy in managing chemotherapy-induced nausea and vomiting (CINV). Methods: A total of 100 patients with gastrointestinal reactions who were hospitalized in the oncology department of Nanning Third People’s Hospital from January to December 2023 were selected as study subjects. They were randomly divided into two groups: the observation group (n = 50) received standard antiemetic treatment in conjunction with Shen-Shi Zhi-Tong plaster and Lei-Huo moxibustion, while the control group (n = 50) received only standard antiemetic treatment and Lei-Huo moxibustion. The occurrence of nausea and vomiting during chemotherapy was recorded using a CINV nursing log, and the incidence rates of acute and delayed vomiting were statistically analyzed. Results: The incidence rate of acute vomiting in the observation group was 42%, significantly lower than the control group’s 64% (P = 0.0300); the incidence rate of delayed vomiting was 36% in the observation group compared to 48% in the control group (P = 0.1900). The mean nausea grade in the observation group was 1.08, significantly lower than 2.02 in the control group (P < 0.0001), and the mean vomiting grade was 0.82, also significantly lower than 1.76 in the control group (P < 0.0001). Conclusion: Shen-Shi Zhi-Tong plaster combined with Lei-Huo moxibustion can effectively reduce the incidence of nausea and vomiting in patients undergoing highly emetogenic chemotherapy and shows good clinical application prospects. This study provides strong support for the adoption of such combined therapies in the prevention and treatment of CINV in the future.