Superficial microbiota disturbances are common in dogs, with Malassezia pachydermatis yeasts often being involved. Topical products are recommended as a first-line management strategy; however, literature regarding specific topical protocols is still scarce. This study aimed to evaluate the performance of a protocol combining chlorhexidine and Ophytrium-containing products in reducing yeast counts in dogs with microscopic evidence of yeast imbalance and dermatological signs. Dogs were shampooed on Day 0 (D0) and then received eight mousse applications at two to three-day intervals. Followed-up parameters on D0, Day 7 (D7), and Day 21 (D21) were microscopic yeast counting, pruritus, and skin irritation scores. At D21, veterinarians’ and owners’ overall assessments were collected. Malassezia pachydermatis counts decreased at D7 (57.3% vs D0, p < 0.05) and at D21 (79.9% vs D0, p < 0.05). Mean pruritus also decreased at D7 vs D0 (58.3%, p < 0.05) and at D21 vs D0 (75%, p < 0.001). Efficacy was described by all veterinarians from good to excellent, and the proposed procedures were evaluated as efficient and practical by the owners in 91.7% of the cases. The protocol using chlorhexidine and Ophytrium shampoo and mousse could be a useful option in dogs presenting imbalances in yeast cutaneous microbiota.
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