The aim of this study was to assess the seroprevalence of viral hepatitis B and C and co-infection with HIV among volunteer blood donors at the blood sampling and distribution depot (BSDD) in Ouahigouya. Patients and methods: Our study population consisted of all volunteer blood donors who had donated during a 2-year period from 1 January 2019 to 31 December 2020. Samples were taken from patients with no contraindications and serological tests were performed using ELISA tests. HBsAg, HCV-Ac and HIV serology were tested. All samples reactive for HIV, HBV and HCV were retested for confirmation using a second enzyme-linked immunosorbent assay. A result was considered positive if both the first and second tests were positive. Results: In two years, the Ouahigouya BSDD recorded 9726 donations, including 7983 new donors and 1743 former donors. The average age of donors was 25.59 years, with a sex ratio of 3.4. The seroprevalence of HBV, HCV and HIV was 7.31%, 3.10% and 2.12% respectively. HBV-HCV co-infection was found in 0.32% of cases, HIV-HBV, HIV-HCV, and HIV-HBV-HCV co-infection were found in 0.25%, 0.09% and 0.04% respectively. Conclusion: The seroprevalence of viral hepatitis B and C remains high among volunteer blood donors in Ouahigouya, although a decline in seroprevalence appears to be on the horizon.
References
[1]
Cui, F., Blach, S., Manzengo Mingiedi, C., Gonzalez, M.A., Sabry Alaama, A., Mozalevskis, A., et al. (2023) Global Reporting of Progress towards Elimination of Hepatitis B and Hepatitis C. TheLancetGastroenterology&Hepatology, 8, 332-342. https://doi.org/10.1016/s2468-1253(22)00386-7
[2]
Meda, N., Tuaillon, E., Kania, D., Tiendrebeogo, A., Pisoni, A., Zida, S., et al. (2018) Hepatitis B and C Virus Seroprevalence, Burkina Faso: A Cross-Sectional Study. BulletinoftheWorldHealthOrganization, 96, 750-759. https://doi.org/10.2471/blt.18.208603
[3]
Al-Waleedi, A.A. and Khader, Y.S. (2012) Prevalence of Hepatitis B and C Infections and Associated Factors among Blood Donors in Aden City, Yemen. EasternMediterraneanHealthJournal, 18, 624-629. https://doi.org/10.26719/2012.18.6.624
[4]
Boushab, B.M., Melaïnine Mohamed Limame, O.C., Zahra, F.F., Mamoudou, S., Roseline Darnycka, B.M. and Saliou, S.M. (2017) Estimation of Seroprevalence of HIV, Hepatitis B and C Virus and Syphilis among Blood Donors in the Hospital of Aïoun, Mauritania. PanAfricanMedicalJournal, 28, Article No. 118. https://doi.org/10.11604/pamj.2017.28.118.12465
[5]
Harry, T.O., Bajani, M.D. and Moses, A.E. (1994) Hepatitis B Virus Infection among Blood Donors and Pregnant Women in Maiduguri, Nigeria. East African Medical Journal, 71, 596-597.
[6]
Kabamba-Tshikongo, A., Manya-Mboni, H., Mwamba-Mulumba, C., Takaisi-Kikuni, N.B., Vandenbroucke, A.T., Pâques, A.T., et al. (2023) Hepatitis C Virus among Blood Donors in Lubumbashi, DRC: Seroprevalence and Molecular Characterisation. TransfusionCliniqueetBiologique, 30, 272-278. https://doi.org/10.1016/j.tracli.2023.02.007
[7]
INSD (2022) 5ème Recensement Général de la Population et de l’Habitat, synthèse des résultats définitifs, INSD.
[8]
Lopez-Balderas, N., Bravo, E., Camara, M. and Hernandez-Romano, P. (2015) Seroprevalence of Hepatitis Viruses and Risk Factors in Blood Donors of Veracruz, Mexico. TheJournalofInfectioninDevelopingCountries, 9, 274-282. https://doi.org/10.3855/jidc.4812
[9]
Luz, E., Marques, M., Netto, E.M., Campos, L.M., Amaral, S., Santana, I., et al. (2022) HIV, HTLV, and Hepatitis B and C Infection in Blood Donors in Bahia, Brazil from 2008 to 2017. Viruses, 14, Article No. 2323. https://doi.org/10.3390/v14112323
[10]
Nagalo, B.M., Bisseye, C., Sanou, M., Kienou, K., Nebié, Y.K., Kiba, A., et al. (2011) Seroprevalence and Incidence of Transfusion‐Transmitted Infectious Diseases among Blood Donors from Regional Blood Transfusion Centres in Burkina Faso, West Africa. TropicalMedicine&InternationalHealth, 17, 247-253. https://doi.org/10.1111/j.1365-3156.2011.02902.x
[11]
Nagalo, M.B., Sanou, M., Bisseye, C., et al. (2011) Seroprevalence of Human Immunodeficiency Virus, Hepatitis B and C Viruses and Syphilis among Blood Donors in Koudougou (Burkina Faso) in 2009. BloodTransfusTrasfusSangue, 9, 419-424.
[12]
Lingani, M., Akita, T., Ouoba, S., Nagashima, S., Boua, P.R., Takahashi, K., et al. (2020) The Changing Epidemiology of Hepatitis B and C Infections in Nanoro, Rural Burkina Faso: A Random Sampling Survey. BMCInfectiousDiseases, 20, Article No. 46. https://doi.org/10.1186/s12879-019-4731-7
[13]
Khattak, M.F., Salamat, N., Bhatti, F.A., et al. (2002) Seroprevalence of Hepatitis B, C and HIV in Blood Donors in Northern Pakistan. JPMA Journal of the Pakistan Medical Association, 52, 398-402.
[14]
Mobarki, A.A., Madkhali, M.M., Dobie, G., Saboor, M., Madkhali, A.M., Madkhli, B., et al. (2022) Patterns of Hepatitis B, Hepatitis C and HIV among Blood Donors in Samtah-Jazan Region. JournalofEpidemiologyandGlobalHealth, 12, 304-310. https://doi.org/10.1007/s44197-022-00051-7
[15]
Mohsenizadeh, M., Mollaei, H.R. and Ghaziizadeh, M. (2017) Seroepidemiological Study of Hepatitis B, C and HIV among Blood Donors in Kerman. Asian Pacific Journal of Cancer Prevention, 18, 3267-3272.
[16]
Nlankpe, A.M., Kwadzokpui, P.K., Adedia, D., Nignan, J.N. and Owiafe, P.K. (2021) Seroepidemiology of Hepatitis B and C Virus Infections: A Five‐Year Retrospective Study among Blood Donors in Saboba District in the Northern Region of Ghana. BioMedResearchInternational, 2021, Article ID: 5599705. https://doi.org/10.1155/2021/5599705
[17]
Koura, M., Héma, A., Coulibaly, A., et al. (2017) Incidence et risque résiduel de transmission des virus de l’hépatite B et C par transfusion sanguine à Bobo-Dioulasso (Burkina Faso): Étude de cohorte. Sciences et Technique Sciences de la santé, December, 25-33.
[18]
Takuissu, G.R., Kenmoe, S., Amougou Atsama, M., Atenguena Okobalemba, E., Mbaga, D.S., Ebogo-Belobo, J.T., et al. (2022) Global Epidemiology of Occult Hepatitis B Virus Infections in Blood Donors, a Systematic Review and Meta-Analysis. PLOSONE, 17, e0272920. https://doi.org/10.1371/journal.pone.0272920
[19]
Zhou, Q., Liu, A., Wang, S., Li, J., He, M. and Chen, L. (2022) Hepatitis c Virus Screening Reactive among Blood Donors in Mainland China: A Systematic Review and Meta‐Analysis. TransfusionMedicine, 33, 147-158. https://doi.org/10.1111/tme.12935
[20]
Buseri, F.I., Muhibi, M.A. and Jeremiah, Z.A. (2009) Sero-Epidemiology of Transfusion-Transmissible Infectious Diseases among Blood Donors in Osogbo, Southwest Nigeria. Blood Transfusion, 7, 293-299.
[21]
Tessema, B., Yismaw, G., Kassu, A., Amsalu, A., Mulu, A., Emmrich, F., et al. (2010) Seroprevalence of HIV, HBV, HCV and Syphilis Infections among Blood Donors at Gondar University Teaching Hospital, Northwest Ethiopia: Declining Trends over a Period of Five Years. BMCInfectiousDiseases, 10, Article No. 111. https://doi.org/10.1186/1471-2334-10-111
[22]
Abate, M. and Wolde, T. (2016) Seroprevalence of Human Immunodeficiency Virus, Hepatitis B Virus, Hepatitis C Virus, and Syphilis among Blood Donors at Jigjiga Blood Bank, Eastern Ethiopia. EthiopianJournalofHealthSciences, 26, 153-160. https://doi.org/10.4314/ejhs.v26i2.9
[23]
Karabaev, B.B., Beisheeva, N.J., Satybaldieva, A.B., Ismailova, A.D., Pessler, F. and Akmatov, M.K. (2017) Seroprevalence of Hepatitis B, Hepatitis C, Human Immunodeficiency Virus, Treponemapallidum, and Co-Infections among Blood Donors in Kyrgyzstan: A Retrospective Analysis (2013-2015). InfectiousDiseasesofPoverty, 6, Article No. 45. https://doi.org/10.1186/s40249-017-0255-9
[24]
Anaedobe, C.G., Fowotade, A., Omoruyi, C. and Bakare, R. (2015) Prevalence, Sociodemographic Features and Risk Factors of Hepatitis B Virus Infection among Pregnant Women in Southwestern Nigeria. PanAfricanMedicalJournal, 20, Article No. 406. https://doi.org/10.11604/pamj.2015.20.406.6206
[25]
Breakwell, L., Tevi-Benissan, C., Childs, L., Mihigo, R. and Tohme, R. (2017) The Status of Hepatitis B Control in the African Region. PanAfricanMedicalJournal, 27, Article No. 17. https://doi.org/10.11604/pamj.supp.2017.27.3.11981
