中医药治疗糖尿病肾病研究进展
Research Progress in the Treatment of Diabetic Nephropathy with Traditional Chinese Medicine

糖尿病肾病(diabetic kidney disease, DKD)是指糖尿病患者由于血糖长期控制不佳，导致尿白蛋白排泄率增加和肾小球滤过率进行性下降，进而引起的肾脏病变。西医在治疗DKD蛋白尿方面，已经有了一些有效的药物，如肾素–血管紧张素系统抑制剂(RASi)、钠–葡萄糖共转运蛋白2抑制剂(SGLT2i)、胰高血糖素样肽-1受体激动剂(GLP-1RA)以及盐皮质激素受体拮抗剂(MRA)等。然而，尽管这些药物能够在一定程度上控制DKD的进展，但尚未找到能够完全逆转或阻止其病程发展的最佳方法。在这种背景下，中医药治疗DKD的研究和应用显得尤为重要。中医药凭借其独特的理论和治疗方法，在糖尿病肾病的治疗中显示出一定的优势和潜力。基于以上，本文将对中医药治疗糖尿病肾病研究进展进行分析，论述中医药治疗DKD的病因病机、辨证分型、方药治疗等内容。
Diabetic kidney disease (DKD) refers to the kidney diseases caused by the increase of urinary albumin excretion rate and the progressive decrease of glomerular filtration rate in diabetic patients due to the long-term poor control of blood sugar. Western medicine has some effective drugs for the treatment of DKD proteinuria, such as renin-angiotensin system inhibitor (RASi), sodium-glucose cotransporter 2 inhibitor (SGLT2i), glucagon-like peptide-1 receptor agonist (GLP-1RA) and salocorticoid receptor antagonist (MRA). However, although these drugs are able to control the progression of DKD to some extent, the best way to completely reverse or stop its progression has not yet been found. In this context, the research and application of traditional Chinese medicine treatment of DKD is particularly important. With its unique theory and treatment methods, traditional Chinese medicine has shown certain advantages and potential in the treatment of diabetic nephropathy. Based on the above, this paper will analyze the research progress of TCM treatment of diabetic nephropathy, and discuss the etiology and pathogenesis, syndrome differentiation and prescription treatment of TCM treatment of DKD.