全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

卵巢癌多学科诊疗模式的现状与展望
Current Status and Prospect of the Diagnosis and Treatment Mode of Multidisciplinary Team in Ovarian Cancer

DOI: 10.12677/acm.2025.151074, PP. 538-545

Keywords: 多学科诊疗(MDT),MDT团队,卵巢癌,优势与局限,未来方向
Multi-Disciplinary Treatment (MDT)
, Multi-Disciplinary Teams, Ovarian Cancer, Advantages and Limitations, Development Tendency

Full-Text   Cite this paper   Add to My Lib

Abstract:

卵巢癌是一种常见妇科恶性肿瘤,侵袭性高、隐匿性强、病死率高、易复发,具有高度异质性和复杂性,传统诊治方法存在局限性。近年来,卵巢癌治疗中多学科诊疗(Multi-Disciplinary Treatment, MDT)模式的作用愈加重要,通过MDT团队协作,可以为患者提供更加全面化、个性化的诊疗方案,更能满足患者需求。本文将对近年来MDT模式在卵巢癌中的相关临床研究进行综述,阐述其在卵巢癌诊治中的优势、局限性及未来方向,旨在为临床实践和未来研究提供参考。
Ovarian cancer is a common gynecological malignant tumor with high invasiveness, high occult, high mortality, easy recurrence, high heterogeneity and complexity, and traditional diagnosis and treatment methods have limitations. Recently, the role of multidisciplinary treatment in ovarian cancer has become more important, and through multi-disciplinary teams, patients can be provided with a more comprehensive and personalized treatment plan to better meet the needs of patients. This paper will review the relevant clinical research of MDT diagnosis and treatment model in ovarian cancer in recent years, explaining its advantages, limitations and future direction in the diagnosis and treatment of ovarian cancer, aiming to provide reference for clinical practice and future research.

References

[1]  中国医师协会妇产科医师分会妇科肿瘤学组, 向阳, 张国楠. 卵巢恶性肿瘤多学科团队协作诊治的中国专家共识[J]. 中华妇产科杂志, 2021, 56(12): 825-830.
[2]  Marijon, E., Narayanan, K., Smith, K., Barra, S., Basso, C., Blom, M.T., et al. (2023) The Lancet Commission to Reduce the Global Burden of Sudden Cardiac Death: A Call for Multidisciplinary Action. The Lancet, 402, 883-936.
https://doi.org/10.1016/s0140-6736(23)00875-9
[3]  Selby, P., Popescu, R., Lawler, M., Butcher, H. and Costa, A. (2019) The Value and Future Developments of Multidisciplinary Team Cancer Care. American Society of Clinical Oncology Educational Book, 39, 332-340.
https://doi.org/10.1200/edbk_236857
[4]  王睆琳, 何谦, 代佳灵, 等. 数智化时代多学科诊疗发展及展望[J]. 华西医学, 2024, 39(1): 6-10.
[5]  马丁. 卵巢癌研究进展与规范化治疗[J]. 中国实用妇科与产科杂志, 2021, 37(6): 601-604.
[6]  Hung, H., Tseng, Y., Chao, H., Chiu, C., Hsu, W., Hsu, H., et al. (2020) Multidisciplinary Team Discussion Results in Survival Benefit for Patients with Stage III Non-Small-Cell Lung Cancer. PLOS ONE, 15, e0236503.
https://doi.org/10.1371/journal.pone.0236503
[7]  Khalafallah, A.M., Jimenez, A.E., Romo, C.G., Kamson, D.O., Kleinberg, L., Weingart, J., et al. (2020) Quantifying the Utility of a Multidisciplinary Neuro-Oncology Tumor Board. Journal of Neurosurgery, 135, 87-92.
https://doi.org/10.3171/2020.5.jns201299
[8]  Liam, C., Liam, Y., Poh, M. and Wong, C. (2020) Accuracy of Lung Cancer Staging in the Multidisciplinary Team Setting. Translational Lung Cancer Research, 9, 1654-1666.
https://doi.org/10.21037/tlcr.2019.11.28
[9]  Falzone, L., Scandurra, G., Lombardo, V., Gattuso, G., Lavoro, A., Distefano, A., et al. (2021) A Multidisciplinary Approach Remains the Best Strategy to Improve and Strengthen the Management of Ovarian Cancer (Review). International Journal of Oncology, 59, Article No. 53.
https://doi.org/10.3892/ijo.2021.5233
[10]  商冠宁. 多学科综合诊疗协作组模式在骨肿瘤规范化诊疗中的应用[J]. 中国肿瘤外科杂志, 2022, 14(5): 417-420.
[11]  Jenkins, N. and Hughes, H. (2020) How I Do It… How Infection Doctors Approach the PJI Mdt. The Knee, 27, 1994-1997.
https://doi.org/10.1016/j.knee.2020.09.005
[12]  姚宏伟, 孙应实, 张晓燕, 等. 结直肠癌多学科综合治疗协作组诊疗模式中国专家共识(2023版) [J]. 中国实用外科杂志, 2024, 44(1): 1-16.
[13]  中国胆道肿瘤多学科综合治疗专家共识[J]. 肿瘤综合治疗电子杂志, 2023, 9(3): 57-68.
[14]  李璡, 温灏, 刘淑娟, 等. 2023年中国卵巢癌诊疗现状白皮书[J]. 中国实用妇科与产科杂志, 2023, 39(12): 1225-1232.
[15]  Bray, F., Laversanne, M., Sung, H., Ferlay, J., Siegel, R.L., Soerjomataram, I., et al. (2024) Global Cancer Statistics 2022: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 74, 229-263.
https://doi.org/10.3322/caac.21834
[16]  Rausei, S., Uccella, S., D’Alessandro, V., Gisone, B., Frattini, F., Lianos, G., et al. (2019) Aggressive Surgery for Advanced Ovarian Cancer Performed by a Multidisciplinary Team: A Retrospective Analysis on a Large Series of Patients. Surgery Open Science, 1, 43-47.
https://doi.org/10.1016/j.sopen.2019.05.005
[17]  Colombo, N., Sessa, C., Bois, A.D., et al. (2019) ESMO-ESGO Consensus Conference Recommendations on Ovarian Cancer: Pathology and Molecular Biology, Early and Advanced Stages, Borderline Tumours and Recurrent Disease. Annals of Oncology, 30, 672-705.
[18]  James, N., Ozsoy, M., Cruz, P.D.L., Woodman, M. and Ribeiro, J. (2021) 729 Immunologic Tumor Cell Intrinsic Effects of Standard of Care Therapies for Ovarian Cancer. Journal for ImmunoTherapy of Cancer, 9, A1-A1054.
https://doi.org/10.1136/jitc-2021-sitc2021.729
[19]  Lheureux, S., Gourley, C., Vergote, I. and Oza, A.M. (2019) Epithelial Ovarian Cancer. The Lancet, 393, 1240-1253.
https://doi.org/10.1016/s0140-6736(18)32552-2
[20]  孟元光, 叶明侠. 卵巢癌肿瘤细胞减灭术的并发症及防治[J]. 中国实用妇科与产科杂志, 2021, 37(6): 627-630.
[21]  Cohen, P., Tan, A.L. and Penman, A. (2009) The Multidisciplinary Tumor Conference in Gynecologic Oncology—Does It Alter Management? International Journal of Gynecological Cancer, 19, 1470-1472.
https://doi.org/10.1111/igc.0b013e3181bf82df
[22]  Greer, H.O., Frederick, P.J., Falls, N.M., et al. (2010) Impact of a Weekly Multidisciplinary Tumor Board Conference on the Management of Women with Gynecologic Malignancies. International Journal of Gynecological Cancer, 20, 1321-1325.
[23]  Lee, B., Kim, K., Choi, J.Y., Suh, D.H., No, J.H., Lee, H., et al. (2017) Efficacy of the Multidisciplinary Tumor Board Conference in Gynecologic Oncology: A Prospective Study. Medicine, 96, e8089.
https://doi.org/10.1097/md.0000000000008089
[24]  Quaranta, M., Nath, R., Mehra, G., Diab, Y. and Sayasneh, A. (2020) Surgery of Benign Ovarian Masses by a Gynecological Cancer Surgeon: A Cohort Study in a Tertiary Cancer Centre. Cureus, 12, e9201.
https://doi.org/10.7759/cureus.9201
[25]  Minig, L., de Santiago, J., Domingo, S., Gil-Moreno, A., Martínez, S., Rodríguez-Garzotto, A., et al. (2018) Optimization of Surgical Treatment of Advanced Ovarian Cancer: A Spanish Expert Perspective. Clinical and Translational Oncology, 21, 656-664.
https://doi.org/10.1007/s12094-018-1967-4
[26]  Mulligan, K.M., Glennon, K., Donohoe, F., O’Brien, Y., Mc Donnell, B.C., Bartels, H.C., et al. (2021) Multidisciplinary Surgical Approach to Increase Complete Cytoreduction Rates for Advanced Ovarian Cancer in a Tertiary Gynecologic Oncology Center. Annals of Surgical Oncology, 28, 4553-4560.
https://doi.org/10.1245/s10434-020-09494-3
[27]  魏炜炜, 钱峻, 胡玉霆, 等. 多学科协作模式指导初治晚期卵巢癌肿瘤细胞减灭术的效果分析[J]. 手术电子杂志, 2022, 9(4): 19-25.
[28]  郭思琴. 腹腔镜检查联合多学科团队指导二次细胞减灭术治疗复发性卵巢癌的前瞻性研究[J]. 中国现代药物应用, 2017, 11(21): 37-38.
[29]  Stefania, R., Maria, G.D., Lucia, M., et al. (2020) Imaging before Cytoreductive Surgery in Advanced Ovarian Cancer Patients. International Journal of Gynecological Cancer, 30, 133-138.
[30]  Lucia, M., Francesco, M., Isabella, B., et al. (2022) Ovarian Cancer in a Northern Italian Province and the Multidisciplinary Team. Cancers (Basel), 15, Article No. 299.
[31]  Tookman, L., Krell, J., Nkolobe, B., Burley, L. and McNeish, I.A. (2020) Practical Guidance for the Management of Side Effects during Rucaparib Therapy in a Multidisciplinary UK Setting. Therapeutic Advances in Medical Oncology, 12, 1-14.
https://doi.org/10.1177/1758835920921980
[32]  Sultova, E., Westphalen, C.B., Jung, A., Kumbrink, J., Kirchner, T., Mayr, D., et al. (2020) NGS-Guided Precision Oncology in Metastatic Breast and Gynecological Cancer: First Experiences at the CCC Munich LMU. Archives of Gynecology and Obstetrics, 303, 1331-1345.
https://doi.org/10.1007/s00404-020-05881-z
[33]  陈秀云, 方玉柳, 谢玲女. 基于多学科合作的卵巢癌减瘤术后相关回肠造口管理[J]. 中国现代医生, 2021, 59(8): 180-182+186.
[34]  卢淮武, 徐冬冬, 赵喜博, 等. 《2024 NCCN卵巢癌包括输卵管癌及原发性腹膜癌临床实践指南(第1版)》解读[J]. 中国实用妇科与产科杂志, 2024, 40(2): 187-197.
[35]  Tischkowitz, M., Huang, S., Banerjee, S., Hague, J., Hendricks, W.P.D., Huntsman, D.G., et al. (2020) Small-Cell Carcinoma of the Ovary, Hypercalcemic Type—Genetics, New Treatment Targets, and Current Management Guidelines. Clinical Cancer Research, 26, 3908-3917.
https://doi.org/10.1158/1078-0432.ccr-19-3797
[36]  Talia, K.L., Parra‐Herran, C. and McCluggage, W.G. (2021) Ovarian Mucinous and Seromucinous Neoplasms: Problematic Aspects and Modern Diagnostic Approach. Histopathology, 80, 255-278.
https://doi.org/10.1111/his.14399
[37]  夏霁, 颜梦宇, 韩凤娟. 卵巢癌中西医结合多学科综合协作诊疗模式新探索[J]. 上海中医药杂志, 2020, 54(1): 5-8+12.
[38]  陈聪. 中药单体槲皮素通过抑制LSD1干预上皮性卵巢癌侵袭的机制研究[D]: [博士学位论文]. 南京: 南京中医药大学, 2017.
[39]  邱楠, 陈小凤, 艾长江, 等. 艾迪注射液联合化疗治疗卵巢癌的疗效及安全性Meta分析[J]. 世界中西医结合杂志, 2019, 14(4): 467-472+480.
[40]  Berry, S., Giraldo, N.A., Green, B.F., Cottrell, T.R., Stein, J.E., Engle, E.L., et al. (2021) Analysis of Multispectral Imaging with the Astropath Platform Informs Efficacy of PD-1 Blockade. Science, 372, eaba2609.
https://doi.org/10.1126/science.aba2609
[41]  Meskó, B. and Görög, M. (2020) A Short Guide for Medical Professionals in the Era of Artificial Intelligence. NPJ Digital Medicine, 3, Article No. 126.
https://doi.org/10.1038/s41746-020-00333-z
[42]  Xu, H., Gong, T., Liu, F., Chen, H., Xiao, Q., Hou, Y., et al. (2022) Artificial Intelligence Performance in Image-Based Ovarian Cancer Identification: A Systematic Review and Meta-analysis. eClinicalMedicine, 53, Article ID: 101662.
https://doi.org/10.1016/j.eclinm.2022.101662
[43]  Lu, H., Arshad, M., Thornton, A., Avesani, G., Cunnea, P., Curry, E., et al. (2019) A Mathematical-Descriptor of Tumor-Mesoscopic-Structure from Computed-Tomography Images Annotates Prognostic-and Molecular-Phenotypes of Epithelial Ovarian Cancer. Nature Communications, 10, Article No. 764.
https://doi.org/10.1038/s41467-019-08718-9
[44]  邱雅, 杨帆, 梁思思, 等. 卵巢癌单病种多学科协作模式的临床实践效果分析[J]. 中国实用妇科与产科杂志, 2021, 37(1): 87-91.
[45]  Chandra, A., Pius, C., Nabeel, M., Nair, M., Vishwanatha, J.K., Ahmad, S., et al. (2019) Ovarian Cancer: Current Status and Strategies for Improving Therapeutic Outcomes. Cancer Medicine, 8, 7018-7031.
https://doi.org/10.1002/cam4.2560
[46]  Timmerman, D., Cibula, D., Planchamp, F., Bourne, T., Landolfo, C., Testa, A.C., et al. (2021) Response to: Correspondence on “ESGO/ISUOG/IOTA/ESGE Consensus Statement on Pre-Operative Diagnosis of Ovarian Tumors” by Thomassin-Nagarra et al. International Journal of Gynecological Cancer, 31, 1396-1397.
https://doi.org/10.1136/ijgc-2021-003013
[47]  Specchia, M.L., Frisicale, E.M., Carini, E., Di Pilla, A., Cappa, D., Barbara, A., et al. (2020) The Impact of Tumor Board on Cancer Care: Evidence from an Umbrella Review. BMC Health Services Research, 20, Article No. 73.
https://doi.org/10.1186/s12913-020-4930-3
[48]  van Roessel, S., Soer, E.C., Daamen, L.A., van Dalen, D., Fariña Sarasqueta, A., Stommel, M.W.J., et al. (2021) Preoperative Misdiagnosis of Pancreatic and Periampullary Cancer in Patients Undergoing Pancreatoduodenectomy: A Multicentre Retrospective Cohort Study. European Journal of Surgical Oncology, 47, 2525-2532.
https://doi.org/10.1016/j.ejso.2021.03.228
[49]  钟文昭, 中国胸部肿瘤研究协作组, 中国抗癌协会肺癌专业委员会, 等. 肺癌多学科团队诊疗中国专家共识[J]. 中华肿瘤杂志, 2020, 42(10): 817-828.
[50]  Bozzini, C., Busti, F., Marchi, G., Vianello, A., Cerchione, C., Martinelli, G., et al. (2024) Anemia in Patients Receiving Anticancer Treatments: Focus on Novel Therapeutic Approaches. Frontiers in Oncology, 14, Article ID: 1380358.
https://doi.org/10.3389/fonc.2024.1380358
[51]  Yao, W., Chen, X., Fan, B., Zeng, L., Zhou, Z., Mao, Z., et al. (2023) Multidisciplinary Team Diagnosis and Treatment of Pancreatic Cancer: Current Landscape and Future Prospects. Frontiers in Oncology, 13, Article ID: 1077605.
https://doi.org/10.3389/fonc.2023.1077605
[52]  Cabitza, E., Pirola, M., Baldessari, C., Bernardelli, G., Zunarelli, E., Pipitone, S., et al. (2023) Cerebellar Metastasis of Ovarian Cancer: A Case Report. Journal of Medical Case Reports, 17, Article No. 553.
https://doi.org/10.1186/s13256-023-04211-6
[53]  Pillay, B., Wootten, A.C., Crowe, H., Corcoran, N., Tran, B., Bowden, P., et al. (2016) The Impact of Multidisciplinary Team Meetings on Patient Assessment, Management and Outcomes in Oncology Settings: A Systematic Review of the Literature. Cancer Treatment Reviews, 42, 56-72.
https://doi.org/10.1016/j.ctrv.2015.11.007
[54]  Maharaj, A.D., Evans, S.M., Zalcberg, J.R., Ioannou, L.J., Graco, M., Croagh, D., et al. (2020) Barriers and Enablers to the Implementation of Multidisciplinary Team Meetings: A Qualitative Study Using the Theoretical Domains Framework. BMJ Quality & Safety, 30, 792-803.
https://doi.org/10.1136/bmjqs-2020-011793

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133