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针灸治疗类风湿关节炎的炎症因子机制的研究进展
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Abstract:
炎症因子是类风湿关节炎(RA)进程中的重要细胞因子，能够促进滑膜炎症、破坏骨与软骨，加重临床症状。针灸，包括普通针刺、电针、温针灸、蜂针等，因患者依从性好、疗效显著、副作用小等特点，在RA的治疗中发挥积极作用。临床研究与基础研究均证明了针灸能通过降低促炎细胞因子和升高抑炎细胞因子来调节机体免疫、调控信号通路、减轻滑膜炎症，使骨与软骨得到保护，RA症状得以改善。文章对近几年针灸在治疗RA中对炎症因子的影响进行综述，为今后RA的临床治疗提供参考与思路。
Inflammatory factors are important cytokines in the progression of Rheumatoid Arthritis (RA), which can promote synovial inflammation, damage bones and cartilage, and worsen clinical symptoms. Acupuncture, including common needling, electroacupuncture, warm needling, and bee venom acupuncture, plays a positive role in the treatment of RA due to characteristics such as good patient compliance, significant efficacy, and minimal side effects. Clinical and basic research have both confirmed that acupuncture can regulate body immunity, control signaling pathways, and reduce synovial inflammation by lowering pro-inflammatory cytokines and increasing anti-inflammatory cytokines, thus protecting bones and cartilage and improving RA symptoms. This article provides a review of the impact of acupuncture on inflammatory factors in the treatment of RA in recent years. It offers references and insights for future clinical treatment of RA.
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