Introduction: Primary polydipsia, frequently observed in patients with schizophrenia, can cause severe hyponatremia, leading to serious complications. Objective: This study reviews the management and prevalence of psychogenic polydipsia, focusing on treatments and clinical outcomes. Methods: Following the PRISMA guidelines, studies on polydipsia in psychiatric patients were included. Data were extracted from databases such as PubMed and Scopus, and a meta-analysis was performed. Results: Fifteen studies were analyzed, totaling 586 patients. The use of urea was effective in correcting hyponatremia, while antipsychotics showed mixed results. Heterogeneity between studies was moderate (I2 = 56%). Conclusion: Psychogenic polydipsia is a severe condition in schizophrenic patients. The use of urea has shown promise, but further studies are needed to optimize treatments.
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