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Long Term Outcomes of Management of Open Fractures of Long Bone among Patients with a Surgical Implant Generation Network Nail at Kumi Orthopaedic Center, Uganda

DOI: 10.4236/ojo.2024.1412055, PP. 589-597

Keywords: Open Fractures, Outcomes, SIGN

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Abstract:

Background: Open fractures are serious injuries with the potential for severe complications such as infection and non-union. Management of open fractures is challenging especially in areas like Uganda where appropriate human resources, infrastructure and medical care are not readily accessible. The introduction of new devices for fracture stabilization and the development of microsurgical procedures for soft tissue reconstruction have greatly improved the management of open fractures. Patients presenting with open fractures of long bones at Kumi Orthopaedic Center are managed with the help of SIGN nail for fracture stabilization. However, long-term outcomes for patients have not been documented. Objective: The objective of this study was to determine the long term outcomes of the management of open fractures of long bones among patients with a Surgical Implant Generation Network (SIGN) nail at Kumi Orthopaedic Center (KOC). Methods: A retrospective study of 39 patients with open fractures who were managed at KOC between 2010 and 2022. Data on patients’ socio-demographic and clinical characteristics and outcomes (both physical and radiographic) was retrieved from the SIGN surgical online database of patients with over 1 year follow up period. Results: The mean age of patients was 40.3 years. The majority were male 32 (82.1%) and the commonest mechanism of injury was Road Traffic Accidents (RTA) 37 (94.9%). The majority did not have a clear record of having received antibiotics immediately after injury 29 (74.4%). However, most had a record of receiving antibiotics 1 hour before surgery 33 (84.6%). The most affected bone was the tibia 33 (84.6%). The commonest fracture type was Gustilo IIIa 18 (46.2%). On follow up; 10 (25.6%) developed an infection (osteomyelitis), 6 (15.4%) did not have a union on x-ray, 4 (10.3%) had a loose screw, 1 had an implant breakage and also 1 patient had a varus deformity. However, there was no amputation recorded. Conclusion: The management of open fractures is still a major challenge in low and middle income countries like Uganda, which is still experiencing relatively high complication rates. Guidelines emphasizing the need for early antibiotic prophylaxis and faster access to surgical treatment are required for better treatment outcomes.

References

[1]  Chalya, P.L., Mabula, J.B., Dass, R.M., Mbelenge, N., Ngayomela, I.H., Chandika, A.B., et al. (2012) Injury Characteristics and Outcome of Road Traffic Crash Victims at Bugando Medical Centre in Northwestern Tanzania. Journal of Trauma Management & Outcomes, 6, Article No. 1.
https://doi.org/10.1186/1752-2897-6-1
[2]  Seid, M., Azazh, A., Enquselassie, F. and Yisma, E. (2015) Injury Characteristics and Outcome of Road Traffic Accident among Victims at Adult Emergency Department of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: A Prospective Hospital Based Study. BMC Emergency Medicine, 15, Article No. 10.
https://doi.org/10.1186/s12873-015-0035-4
[3]  Elniel, A.R. and Giannoudis, P.V. (2018) Open Fractures of the Lower Extremity. EFORT Open Reviews, 3, 316-325.
https://doi.org/10.1302/2058-5241.3.170072
[4]  Meara, J.G., Leather, A.J.M., Hagander, L., Alkire, B.C., Alonso, N., Ameh, E.A., et al. (2015) Global Surgery 2030: Evidence and Solutions for Achieving Health, Welfare, and Economic Development. The Lancet, 386, 569-624.
https://doi.org/10.1016/s0140-6736(15)60160-x
[5]  Mathieu, L., Potier, L., Ndiaye, R., Mbaye, E., Sene, M., Faye, M., et al. (2019) Management of Gustilo Type IIIB Open Tibial Shaft Fractures with Limited Resources: Experience from an African Trauma Center. European Journal of Trauma and Emergency Surgery, 47, 217-223.
https://doi.org/10.1007/s00068-019-01223-0
[6]  Callese, T.E., Richards, C.T., Shaw, P., Schuetz, S.J., Paladino, L., Issa, N., et al. (2015) Trauma System Development in Low and Middle-Income Countries: A Review. Journal of Surgical Research, 193, 300-307.
https://doi.org/10.1016/j.jss.2014.09.040
[7]  Wong, E.G., Gupta, S., Deckelbaum, D.L., Razek, T. and Kushner, A.L. (2015) Prioritizing Injury Care: A Review of Trauma Capacity in Low and Middle-Income Countries. Journal of Surgical Research, 193, 217-222.
https://doi.org/10.1016/j.jss.2014.08.055
[8]  B Card, E., E Obayemi, J., Shirima, O., Rajaguru, P., Massawe, H., Premkumar, A., et al. (2021) Patient Patronage and Perspectives of Traditional Bone Setting at an Outpatient Orthopaedic Clinic in Northern Tanzania. African Health Sciences, 21, 418-26.
https://doi.org/10.4314/ahs.v21i1.52
[9]  Nwachukwu, B.U. (2011) Traditional Bonesetters and Contemporary Orthopaedic Fracture Care in a Developing Nation: Historical Aspects, Contemporary Status and Future Directions. The Open Orthopaedics Journal, 5, 20-26.
https://doi.org/10.2174/1874325001105010020
[10]  Gustilo, R.B., Mendoza, R.M. and Williams, D.N. (1984) Problems in the Management of Type III (Severe) Open Fractures. The Journal of Trauma: Injury, Infection, and Critical Care, 24, 742-746.
https://doi.org/10.1097/00005373-198408000-00009
[11]  Kouassi, K.J., Manon, J., Fonkoue, L., Detrembleur, C. and Cornu, O. (2021) Treatment of Open Tibia Fractures in Sub-Saharan African Countries: A Systematic Review. Acta Orthopaedica Belgica, 87, 85-92.
https://doi.org/10.52628/87.1.11
[12]  Fonkoue, L., Muluem, K.O., Nana, T., Kong, D., Ngongang, O., Ngo Yamben, M.A., et al. (2023) Outcome of a 2-Stage Management of Open Tibia Fracture in a Low-Income Country Lacking Plastic Surgeons: A Retrospective Cohort Study. Orthoplastic Surgery, 13, 25-30.
https://doi.org/10.1016/j.orthop.2023.07.001
[13]  Turley, L., Barry, I. and Sheehan, E. (2023) Frequency of Complications in Intramedullary Nailing of Open Tibial Shaft Fractures: A Systematic Review. EFORT Open Reviews, 8, 90-99.
https://doi.org/10.1530/eor-22-0076
[14]  Yang, Z., Xu, C., Zhu, Y., Li, J., Wu, Z., Zou, J., et al. (2021) Radical Treatment of Severe Open Fractures of Extremities by Orthoplastic Surgery: A 10-Year Retrospective Study. Journal of Orthopaedic Surgery and Research, 16, Article No. 340.
https://doi.org/10.1186/s13018-021-02479-2
[15]  Craig, J., Fuchs, T., Jenks, M., Fleetwood, K., Franz, D., Iff, J., et al. (2014) Systematic Review and Meta-Analysis of the Additional Benefit of Local Prophylactic Antibiotic Therapy for Infection Rates in Open Tibia Fractures Treated with Intramedullary Nailing. International Orthopaedics, 38, 1025-1030.
https://doi.org/10.1007/s00264-014-2293-2
[16]  Lack, W.D., Karunakar, M.A., Angerame, M.R., Seymour, R.B., Sims, S., Kellam, J.F., et al. (2015) Type III Open Tibia Fractures. Journal of Orthopaedic Trauma, 29, 1-6.
https://doi.org/10.1097/bot.0000000000000262
[17]  Rodriguez, L., Jung, H.S., Goulet, J.A., Cicalo, A., Machado-Aranda, D.A. and Napolitano, L.M. (2014) Evidence-Based Protocol for Prophylactic Antibiotics in Open Fractures. Journal of Trauma and Acute Care Surgery, 77, 400-408.
https://doi.org/10.1097/ta.0000000000000398
[18]  Chang, Y., Kennedy, S.A., Bhandari, M., Lopes, L.C., Bergamaschi, C.D.C., Carolina de Oliveira e Silva, M., et al. (2015) Effects of Antibiotic Prophylaxis in Patients with Open Fracture of the Extremities. JBJS Reviews, 3, e2.
https://doi.org/10.2106/jbjs.rvw.n.00088
[19]  Chang, Y., Bhandari, M., Zhu, K.L., Mirza, R.D., Ren, M., Kennedy, S.A., et al. (2019) Antibiotic Prophylaxis in the Management of Open Fractures. JBJS Reviews, 7, e1.
https://doi.org/10.2106/jbjs.rvw.17.00197
[20]  Srour, M., Inaba, K., Okoye, O., Chan, C., Skiada, D., Schnüriger, B., et al. (2015) Prospective Evaluation of Treatment of Open Fractures. JAMA Surgery, 150, 332-336.
https://doi.org/10.1001/jamasurg.2014.2022
[21]  Foote, C.J., Tornetta, P., Reito, A., Al-Hourani, K., Schenker, M., Bosse, M., et al. (2020) A Reevaluation of the Risk of Infection Based on Time to Debridement in Open Fractures. Journal of Bone and Joint Surgery, 103, 265-273.
https://doi.org/10.2106/jbjs.20.01103
[22]  Singh, A., Agarwal, A., Mohan, R., Singh, S., Tewari, P. and Srivastava, S. (2023) The Effect of Timing of Debridement and Surgical Intervention in Open Fractures on the Rate of Infection and Surgical Outcomes: A Prospective Study in a Tertiary Care Setup. Cureus, 15, e37204.
https://doi.org/10.7759/cureus.37204
[23]  Guo, C., Ma, J., Ma, x., Wang, Y., Sun, L., Lu, B., et al. (2018) Comparing Intramedullary Nailing and Plate Fixation for Treating Distal Tibail Fractures: A Meta-Analysis of Randomized Controlled Trials. International Journal of Surgery, 53, 5-11.
https://doi.org/10.1016/j.ijsu.2018.03.026
[24]  Ford, A.N., Harkin, E.A., Lyons, M.M., Summers, H.D., Hecht, G.G., Lack, W.D., et al. (2021) Clinical and Radiographic Predictors of Nonunion in Open Tibial Shaft Fractures. Orthopedics, 44, 142-147.
https://doi.org/10.3928/01477447-20210416-04
[25]  Penzkofer, R., Maier, M., Nolte, A., von Oldenburg, G., Püschel, K., Bühren, V., et al. (2008) Influence of Intramedullary Nail Diameter and Locking Mode on the Stability of Tibial Shaft Fracture Fixation. Archives of Orthopaedic and Trauma Surgery, 129, 525-531.
https://doi.org/10.1007/s00402-008-0700-0
[26]  Tian, R., Zheng, F., Zhao, W., Zhang, Y., Yuan, J., Zhang, B., et al. (2020) Prevalence and Influencing Factors of Nonunion in Patients with Tibial Fracture: Systematic Review and Meta-Analysis. Journal of Orthopaedic Surgery and Research, 15, Article No. 377.
https://doi.org/10.1186/s13018-020-01904-2
[27]  Mills, L., Tsang, J., Hopper, G., Keenan, G. and Simpson, A.H.R.W. (2016) The Multifactorial Aetiology of Fracture Nonunion and the Importance of Searching for Latent Infection. Bone & Joint Research, 5, 512-519.
https://doi.org/10.1302/2046-3758.510.bjr-2016-0138

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