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卒中后抑郁的发病机制和治疗研究进展
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Abstract:
卒中后抑郁(PSD)是一种以情绪低落、兴趣丧失、自我评价降低、食欲下降、失眠等为主要症状的慢性疾病，是脑卒中患者常见的并发症之一，同时也是导致脑卒中患者残疾和死亡的主要原因之一。根据最新国外相关研究显示，PSD可增加20%~50%的脑卒中患者再住院率和死亡率，缩短生存时间。而据我国相关研究发现，在我国脑卒中患者中约有20%~30%会发生PSD，这意味着PSD已成为影响我国脑卒中患者生活质量的重要因素。本文通过对PSD的发病机制、治疗方面的最新研究进展作一综述，以期为相关领域的研究提供参考。
Post-stroke depression (PSD) is a chronic disease characterized by symptoms such as low mood, loss of interest, reduced self-esteem, decreased appetite, and insomnia. PSD is one of the common complications in stroke patients and significantly impacts their quality of life. It is one of the main causes leading to disability and death among stroke patients. International studies have shown that PSD can increase the rate of rehospitalization and mortality by 20% to 50% in stroke patients, and it can also shorten their survival time. Studies in China have also found that about 20% to 30% of stroke patients may develop PSD, making it a significant factor affecting the quality of life of stroke patients in our country. This article primarily reviews the latest research progress in the pathogenesis and treatment of PSD, aiming to provide a reference for clinicians.
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