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53例子宫腺肌病患者临床理化指标分析
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Abstract:
目的：分析子宫腺肌病(adenomyosis)的临床理化指标特征，并探讨腺肌病与炎症状态、营养状态及高凝状态的相关性。方法：回顾性收集2021年1月~2022年12月于广东省中医院53例经手术和病理诊断确认的子宫腺肌病患者病历资料作为研究对象，50例其他良性妇科疾病患者病历资料作为对照组。采用SPSS 24.0软件进行数据处理比较两组的全血细胞计数、凝血功能指标、肝肾功能指标以及炎症相关指标，包括单核细胞与淋巴细胞比值(monocyte/lymphocyte ratio, MLR)、血小板与淋巴细胞比值(platelet/lymphocyte ratio, PLR)等。结果：子宫腺肌病患者的单核细胞计数(P = 0.012)、血小板计数(P < 0.000)、MLR (P = 0.013)和PLR (P = 0.01)均显著高于对照组，而血红蛋白(P < 0.000)、总胆红素(P = 0.001)和白蛋白(P=0.002)水平则显著低于对照组。结论：本研究发现子宫腺肌病患者在临床理化检验方面存在一定的特征。呈现出一定的炎症反应状态、低营养状态、高凝状态。
Objective: This paper aims to analyze the clinical and physicochemical characteristics of adenomyosis and investigate the correlation between adenomyosis and inflammatory status, nutritional status, and hypercoagulable state. Methods: The medical records of 53 patients diagnosed with adenomyosis through surgical and pathological diagnosis were included as the subjects of this study, at Guangdong Provincial Hospital of Traditional Chinese Medicine from January 2021 to December 2022, whereas the records of 50 patients in other benign gynecological conditions served as the control group. Data processing was conducted by SPSS 24.0 software to compare the complete blood count (CBC), coagulation function test indexes, liver and renal function tests, and inflammation markers (including the monocyte/lymphocyte ratio (MLR), platelet/lymphocyte ratio (PLR), etc.) between the two groups; Results: Patients with adenomyosis exhibited significantly elevated monocyte counts (P = 0.012), platelet counts (P < 0.000), MLR (P=0.013) and PLR (P = 0.01) compared to the control group. Conversely, levels of hemoglobin (P < 0.000), total bilirubin (P = 0.001), and albumin (P = 0.002) were notably lower than those observed in the control group. Conclusion: This study has identified certain clinical and biochemical characteristics in patients with adenomyosis. These characteristics include states of inflammation, malnutrition, and hypercoagulability.
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