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分娩镇痛及剖宫产围麻醉期促子宫收缩药物的应用及影响
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Abstract:
在自然分娩及剖宫产术的围术期中，子宫收缩药物的应用日益广泛，其目的是用于预防和治疗产后出血(PPH)。无论是在自然分娩过程中还是在剖宫产过程中，麻醉医生均扮演着不可或缺的角色，他们的深度参与要求对这一类药物有深入的理解与掌握。鉴于此，本文旨在系统性地探讨子宫收缩药物(缩宫素、卡贝缩宫素、欣母沛、米索前列醇、卡孕栓、马来酸麦角新碱)的最新临床应用进展(具体包括药物分类、作用机制、剂量用法、在预防或治疗子宫收缩乏力中的应用、对血流动力学的影响以及其他不良反应)，从而为麻醉科医师及相关医疗人员提供有价值的参考。
The use of uterotonics is becoming increasingly widespread in the perioperative period of both natural delivery and cesarean section for the purpose of preventing and treating postpartum hemorrhage (PPH). Anesthesiologists play an indispensable role both during spontaneous delivery and cesarean section, and their deep involvement requires an in-depth understanding and mastery of this class of drugs. In light of this, the present paper aims to systematically explore the latest clinical advancements in the use of uterotonics (including Oxytocin, Carbetocin, Hemabate, Misoprostol, Carboprost, and Ergonovine Maleate), including their classification, mechanism of action, dosage and administration, application in preventing or treating uterine atony, effects on hemodynamics, and other adverse reactions. This will provide valuable reference information for anesthesiologists and related healthcare professionals.
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