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直肠癌术后吻合口瘘相关危险因素研究进展
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Abstract:
直肠癌术后吻合口瘘是一种严重的并发症，影响患者的恢复和生存质量。近年来，研究者们对其相关危险因素进行了广泛探讨。吻合口瘘的发生可能与多种因素有关，包括患者的临床特征(如年龄、性别、基础疾病)、手术技术(如吻合方式)、围手术期管理(如营养支持、肠道准备)等。研究表明，术前评估和个体化治疗可以显著降低吻合口瘘的发生率。本文旨在总结目前直肠癌术后吻合口瘘相关危险因素的研究进展，为进一步明确各因素之间的关系，以及指导临床实践提供更为坚实的依据。
Anastomotic leakage after rectal cancer surgery is a serious complication, which affects the recovery and quality of life of patients. In recent years, researchers have extensively explored its associated risk factors. The occurrence of anastomotic leakage may be related to a variety of factors, including the clinical characteristics of the patient (e.g., age, gender, underlying disease), surgical techniques (e.g., type of anastomosis), perioperative management (e.g., nutritional support, bowel preparation), and so on. Preoperative assessment and individualized treatment can significantly reduce the incidence of anastomotic leakage. The purpose of this paper is to summarize the research progress of the risk factors of anastomotic leakage after rectal cancer operation, and to provide a more solid basis for further clarifying the relationship between the factors and guiding clinical practice.
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