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Vogt–小柳–原田综合征继发青光眼1例
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Abstract:
Vogt–小柳–原田综合征是一种以双眼弥漫性渗出性肉芽肿性葡萄膜炎为特征，伴有听觉功能障碍、脑膜刺激征及皮肤毛发变白等眼外表现的自身免疫性疾病，青光眼是其最具破坏性的并发症之一，它会导致不可逆的视野缺损和视力丧失，因此准确识别眼压升高的原因，选择合适的降眼压方式才能及时挽救患者的视力。现将就诊于我院的1例Vogt-小柳-原田综合征继发青光眼患者进行报道。
Vogt-Koyanagi-Harada Syndrome is an autoimmune disease characterized by diffuse exudative granulomatous uveitis in both eyes with extraocular manifestations such as auditory dysfunction, meningeal irritation signs, and whitening of the skin and hairs, etc. Glaucoma is one of the most devastating complications, leading to irreversible visual field defects and loss of vision, so accurately identifying the cause of elevated intraocular pressure (IOP) and choosing the right IOP-lowering modality is the only way to save a patient’s vision in time. We report a case of glaucoma secondary to Vogt-Koyanagi-Harada Syndrome in our hospital.
| [1] | Hao, T., Yang, L., Li, B., Chen, X., Li, D. and Liu, X. (2020) Epidemiology of 2000 Chinese Uveitis Patients from Northeast China. British Journal of Ophthalmology, 105, 317-321. https://doi.org/10.1136/bjophthalmol-2020-316256 |
| [2] | Du, L., Kijlstra, A. and Yang, P. (2016) Vogt-Koyanagi-Harada Disease: Novel Insights into Pathophysiology, Diagnosis and Treatment. Progress in Retinal and Eye Research, 52, 84-111. https://doi.org/10.1016/j.preteyeres.2016.02.002 |
| [3] | Moorthy, R.S., Inomata, H. and Rao, N.A. (1995) Vogt-Koyanagi-Harada Syndrome. Survey of Ophthalmology, 39, 265-292. https://doi.org/10.1016/s0039-6257(05)80105-5 |
| [4] | Yang, P., Ren, Y., Li, B., Fang, W., Meng, Q. and Kijlstra, A. (2007) Clinical Characteristics of Vogt-Koyanagi-Harada Syndrome in Chinese Patients. Ophthalmology, 114, 606-614.E3. https://doi.org/10.1016/j.ophtha.2006.07.040 |
| [5] | Read, R.W., Holland, G.N., Rao, N.A., Tabbara, K.F., Ohno, S., Arellanes-Garcia, L., et al. (2001) Revised Diagnostic Criteria for Vogt-Koyanagi-Harada Disease: Report of an International Committee on Nomenclature. American Journal of Ophthalmology, 131, 647-652. https://doi.org/10.1016/s0002-9394(01)00925-4 |
| [6] | 中华医学会眼科学分会眼免疫学组, 中国医师协会眼科医师分会葡萄膜炎与免疫学组. 中国福格特-小柳-原田综合征临床诊疗专家共识(2023年) [J]. 中华眼科杂志, 2023, 59(7): 518-525. |
| [7] | 黄果, 杨培增. Vogt小柳原田综合征的治疗进展[J]. 国际眼科杂志, 2017, 17(6): 1082-1086. |
| [8] | Pandey, A., Balekudaru, S., Venkatramani, D.V., George, A.E., Lingam, V. and Biswas, J. (2016) Incidence and Management of Glaucoma in Vogt Koyanagi Harada Disease. Journal of Glaucoma, 25, 674-680. https://doi.org/10.1097/ijg.0000000000000400 |
| [9] | Veerappan, M., Fleischman, D., Ulrich, J.N., Stinnett, S.S., Jaffe, G.J. and Allingham, R.R. (2016) The Relationship of Vogt-Koyanagi-Harada Syndrome to Ocular Hypertension and Glaucoma. Ocular Immunology and Inflammation, 25, 748-752. https://doi.org/10.1080/09273948.2016.1189578 |
| [10] | Yang, P., Wang, C., Su, G., Pan, S., Qin, Y., Zhang, J., et al. (2020) Prevalence, Risk Factors and Management of Ocular Hypertension or Glaucoma in Patients with Vogt-Koyanagi-Harada Disease. British Journal of Ophthalmology, 105, 1678-1682. https://doi.org/10.1136/bjophthalmol-2020-316323 |
| [11] | Moorthy, R.A.S., Mermoud, A.N., Baerveldt, G., Minckler, D.S., Lee, P.P. and Rao, N.A. A. (1997) Glaucoma Associated with Uveitis. Survey of Ophthalmology, 41, 361-394. https://doi.org/10.1016/s0039-6257(97)00006-4 |
| [12] | Rao, P.V., Deng, P.F., Kumar, J. and Epstein, D.L. (2001) Modulation of Aqueous Humor Outflow Facility by the Rho Kinase-Specific in-Hibitor Y-27632. Investigative Ophthalmology & Visual Science, 42, 1029-1037. |
| [13] | Siddique, S.S., Suelves, A.M., Baheti, U. and Foster, C.S. (2013) Glaucoma and Uveitis. Survey of Ophthalmology, 58, 1-10. https://doi.org/10.1016/j.survophthal.2012.04.006 |
| [14] | Sharon, Y., Friling, R., Luski, M., Campoverde, B.Q., Amer, R. and Kramer, M. (2016) Uveitic Glaucoma: Long-Term Clinical Outcome and Risk Factors for Progression. Ocular Immunology and Inflammation, 25, 740-747. https://doi.org/10.1080/09273948.2016.1255341 |
| [15] | Merayo-Lloves, J., Power, W.J., Rodriguez, A., Pedroza-Seres, M. and Foster, C.S. (1999) Secondary Glaucoma in Patients with Uveitis. Ophthalmologica, 213, 300-304. https://doi.org/10.1159/000027443 |
| [16] | Shrestha, S., Thapa, M. and Shah, D.N. (2013) Pattern of Intraocular Pressure Fluctuation in Uveitic Eyes Treated with Corticosteroids. Ocular Immunology and Inflammation, 22, 110-115. https://doi.org/10.3109/09273948.2013.824106 |
| [17] | Kishi, A., Nao-i, N. and Sawada, A. (1996) Ultrasound Biomicroscopic Findings of Acute Angle-Closure Glaucoma in Vogt-Koyanagi-Harada Syndrome. American Journal of Ophthalmology, 122, 735-737. https://doi.org/10.1016/s0002-9394(14)70498-2 |
| [18] | Gohdo, T. and Tsukahara, S. (1996) Ultrasound Biomicroscopy of Shallow Anterior Chamber in Vogt-Koyanagi-Harada Syndrome. American Journal of Ophthalmology, 122, 112-114. https://doi.org/10.1016/s0002-9394(14)71973-7 |
| [19] | Yao, J., Chen, Y., Shao, T., Ling, Z., Wang, W. and Qian, S. (2013) Bilateral Acute Angle Closure Glaucoma as a Presentation of Vogt-Koyanagi-Harada Syndrome in Four Chinese Patients: A Small Case Series. Ocular Immunology and Inflammation, 21, 286-291. https://doi.org/10.3109/09273948.2013.792937 |
| [20] | Yang, P., Liu, X., Zhou, H., Guo, W., Zhou, C. and Kijlstra, A. (2011) Vogt-Koyanagi-Harada Disease Presenting as Acute Angle Closure Glaucoma at Onset. Clinical & Experimental Ophthalmology, 39, 639-647. https://doi.org/10.1111/j.1442-9071.2011.02523.x |
| [21] | Rathinam, S.R., Namperumalsamy, P., Nozik, R.A. and Cunningham, E.T. (1997) Angle Closure Glaucoma as a Presenting Sign of Vogt-Koyanagi-Harada Syndrome. British Journal of Ophthalmology, 81, 608a. https://doi.org/10.1136/bjo.81.7.608a |
| [22] | Forster, D.J., Rao, N.A., Hill, R.A., Nguyen, Q.H. and Baerveldt, G. (1993) Incidence and Management of Glaucoma in Vogt-Koyanagi-Harada Syndrome. Ophthalmology, 100, 613-618. https://doi.org/10.1016/s0161-6420(93)31604-0 |
| [23] | Ceballos, E.M., Beck, A.D. and Lynn, M.J. (2002) Trabeculectomy with Antiproliferative Agents in Uveitic Glaucoma. Journal of Glaucoma, 11, 189-196. https://doi.org/10.1097/00061198-200206000-00005 |
