Bacterial meningitis, due to Listeria monocytogenes, is an invasive central nervous infection, commonly reported in high-risk subjects such as pregnant women, infants, the elderly and immunocompromised patients. However, in health immunocompetent individuals, bacterial meningitis by this pathogen is extremely rare. Here, we report a case of meningitis due to Listeria monocytogenes in a healthy immunocompetent 10-year-old male child in Cameroon. The child was successfully treated with intravenous ampicillin and recovered without any neurological sequelae. Monitoring, set-up of prompt diagnosis as well as the administration of an adequate antibiotic treatment is essential to both prevent emergence of new case and achieve the best treatment outcome.
References
[1]
Namale, V.S., Kim, C., Sun, Y., Cursio, A., Navis, A., Idro, R. and Thakur, K.T. (2020) Etiologies of Community Acquired Bacterial Meningitis and Antibiotic Resistance Patterns in Africa over the Last 30 Years: A Systematic Review. Journal of Neurology and Neurophysiology, 11, 1-6.
[2]
Valenti, M., Ranganathan, N., Moore, L.S. and Hughes, S. (2021) Listeria monocytogenes Infections: Presentation, Diagnosis and Treatment. British Journal of Hospital Medicine, 82, 1-6. https://doi.org/10.12968/hmed.2021.0107
[3]
Castellazzi, M.L., Marchisio, P. and Bosis, S. (2018) Listeria Monocytogenes Meningitis in Immunocompetent and Healthy Children: A Case Report and a Review of the Literature. Italian Journal of Pediatrics, 44, Article No. 152. https://doi.org/10.1186/s13052-018-0595-5
[4]
Koulla-Shiro, S., Mbuagbaw, J., Kuaban, C. and Zeh, A.K. (1997) Etiology and Outcome of Adult Bacterial Meningitis in Yaoundé, Cameroon. International Journal of Infectious Diseases, 2, 9-11. https://doi.org/10.1016/s1201-9712(97)90003-5
[5]
Mortaji, S., Dacier, P., Mercken, B., Mulder, A. and Misson, J.P. (2019) Listeria Monocytogenes Sepsis. Fatal Course in an Immunocompetent Child. Revue Médicale de Liège, 74, 410-413.
[6]
Société Française de Microbiologie (2022) Comité de l’Antibiogramme de la Société Française de Microbiologie. https://www.sfm-microbiologie.org/wp-content/uploads/2022/05/CASFM2022_V1.0.pdf
[7]
Brisca, G., La Valle, A., Campanello, C., Pacetti, M., Severino, M., Losurdo, G., et al. (2020) Listeria Meningitis Complicated by Hydrocephalus in an Immunocompetent Child: Case Report and Review of the Literature. Italian Journal of Pediatrics, 46, Article No. 111. https://doi.org/10.1186/s13052-020-00873-w
[8]
Sotgiu, G., Muresu, N., Dettori, M., Mura, E., Cossu, A., Dolores Masia, M., et al. (2018) A Case of Listeria Monocytogenes ST-219 Meningo-Encephalitis. International Journal of Environmental Research and Public Health, 16, Article 8. https://doi.org/10.3390/ijerph16010008
[9]
Nesher, L., Hadi, C.M., Salazar, L., Wootton, S.H., Garey, K.W., Lasco, T., et al. (2015) Epidemiology of Meningitis with a Negative CSF Gram Stain: Under-Utilization of Available Diagnostic Tests. Epidemiology and Infection, 144, 189-197. https://doi.org/10.1017/s0950268815000850
[10]
Mo, T., Wu, F., Dou, X., Wang, D., Xia, H. and Li, X. (2022) A Retrospective Study of Rare Listeria Meningoencephalitis in Immunocompetent Children in China. Frontiers in Neurology, 13, Article 827145. https://doi.org/10.3389/fneur.2022.827145
[11]
Hasbun, R. (2022) Progress and Challenges in Bacterial Meningitis: A Review. JAMA, 328, 2147-2154. https://doi.org/10.1001/jama.2022.20521
