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麻醉药物对结直肠癌患者免疫系统影响的研究进展
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Abstract:
结直肠癌(CRC)是一种在临床上常见的消化系统恶性肿瘤，目前我国主要的治疗方式是进行外科手术。结直肠肿瘤可使患者的免疫系统受到抑制，而围术期使用的各种麻醉药物在产生镇痛、抗炎和控制应激反应作用的同时，对结直肠癌患者的免疫功能也会产生多种影响，直接或间接地影响肿瘤的进展和复发，以及结直肠癌患者的预后。本文综述了近年来各种麻醉药物对结直肠癌患者免疫系统影响的研究进展，包括对肿瘤预后的影响。未来的研究应着重于围术期的各种麻醉药物对患者免疫系统的复合影响，以及作用机制，为麻醉提供更加严格的标准。
Colorectal cancer (CRC) is a malignant tumor of the digestive system that is very prevalent worldwide, and the main treatment modality in our country is to perform surgery. Colorectal tumors can suppress the immune system of patients, and the various anesthetic drugs used in the perioperative period will have a variety of effects on the immune function of colorectal cancer patients while producing analgesic, anti-inflammatory and stress control effects, directly or indirectly affecting the progression and recurrence of tumors, as well as the prognosis of colorectal cancer patients. This paper reviews the progress of research on the effects of various anaesthetic drugs on the immune system of colorectal cancer patients in recent years, including the impact on tumour prognosis. Future studies should focus on the compound effects of various anaesthetic drugs on the patient's immune system during the perioperative period, as well as the mechanism of action, to provide more rigorous standards for anaesthesia.
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