Mechanisms and Prevention of Acceleration Exposure-Induced Cardiovascular Injuries

Background: The development of high-performance flighter aircraft requires better anti-G ability of aircrew. Under the influence of continuous ±Gz or ±Gx acceleration, aircrew can suffer from cardiovascular change or injuries, which pose a huge threat to flight safety. In recent years, some achievements have been made in the physiological research of sustained ±Gz or ±Gx acceleration, especially the research on the cardiovascular physiological mechanism of sustained ±Gz or ±Gx acceleration. This paper analyzes the research progress. Methods: Original studies of any related fields will be included in the analysis. Searching of databases and manual scanning of the reference lists of the articles found during the original search will be performed. The following data items of included studies will be abstracted for analysis: publication year, first author, country, institution, journal and research priorities. Results: 28 papers were included in this study. The annual number of publications showed an ascending tendency as a whole and reached its peak in 2014 with a total of 6 documents. The country with the most publications was China. The journals of these papers focused on different fields, including military medicine, integrative medicine, preventive medicine, space medicine, environmental medicine and pharmacology. Research priorities mainly covered cardiac arrhythmia, cardiac structure, cardiovascular function, myocardial injury and myocardial enzyme. Conclusions: This paper analyzes the progress of research in the cardiovascular compensatory response. It is expected to provide reference for subsequent exploration of the mechanism of sustained ±Gz or ±Gx acceleration and the selection of ways to protect against anti-G.