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预测急性胰腺炎严重程度及预后的研究进展
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Abstract:
急性胰腺炎是消化系统最常见的疾病之一，通常是由于胰腺自身的胰酶激活引起胰腺局部炎症反应的疾病，通常与各类病因相关，可以发生各种并发症，病情变化快，严重时可以危及患者的生命。当患者为重症急性胰腺炎(SAP)时，病情进展快，病程长，预后差，伴随高死亡率，因此尽早地对患者的病情及严重程度进行评估，给予早期的干预与治疗，有利于降低患者死亡率，改善预后。近年来已经出现各种评分系统以及临床上常用的实验室指标及影像学对急性胰腺炎的严重程度以及预后进行评估，对于患者后期的病情发展控制及改善预后有较大帮助。本文就近年来国内外评分系统以及临床上常用的实验室指标对预测急性胰腺炎严重程度及预后发展方面的研究进行综述。
Acute pancreatitis is one of the most common diseases in the digestive system. It is usually a disease in which the activation of pancreatic enzymes in the pancreas itself causes a local inflammatory reaction in the pancreas, and it is usually related to various etiologies. Various complications can occur, the condition changes rapidly, and in severe cases, it can endanger the patient’s life. When a patient has severe acute pancreatitis (SAP), the disease progresses rapidly, the disease course is long, the prognosis is poor, and it is accompanied by a high mortality rate. Therefore, evaluating the patient’s condition and severity as early as possible and providing early intervention and treatment are conducive to reducing the patient’s mortality rate and improving the prognosis. In recent years, various scoring systems, commonly used clinical laboratory indicators, and imaging have emerged to evaluate the severity and prognosis of acute pancreatitis, which are of great help for the control of the patient’s later-stage disease development and the improvement of prognosis. This article reviews the research on domestic and foreign scoring systems and commonly used clinical laboratory indicators in recent years regarding the prediction of the severity and prognosis development of acute pancreatitis.
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