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分子影像学在结直肠癌免疫治疗中的研究进展
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Abstract:
结直肠癌是常见的恶性肿瘤，近年来免疫治疗已经成为继手术、化学疗法和放射疗法之后的主要治疗手段，且取得了很好的疗效。由于患者个体化差异存在，免疫治疗前或治疗中需要密切监测体内疾病相关的免疫变化，从而制定个性化、精准化的治疗方案。分子影像技术可以从细胞或分子水平上更好地监测肿瘤免疫治疗的反应，选择合适的靶点及示踪剂是分子成像的重要环节。本文将就分子影像学在结直肠癌免疫治疗监测方面的应用作综述。
Colorectal cancer is a common malignant tumor. In recent years, the immunotherapy has become the main treatment means after surgery, chemotherapy and radiotherapy, and has achieved great efficacy. Due to the existence of individualized differences in patients, immunotherapy requires close monitoring of disease-related immune changes in the body before or during treatment, so as to formulate personalized and precise treatment plans. Molecular imaging technology can better monitor the response to tumor immunotherapy at the cellular or molecular level, and the selection of appropriate targets and tracers is an important part of molecular imaging. In this paper, we will review the application of molecular imaging in the monitoring of immunotherapy for colorectal cancer.
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