Introduction: Coronavirus disease is a pandemic discovered in December 2019. It is a polymorphic, systemic zoonosis caused by a virus with predominant respiratory tropism. This work aimed to evaluate the epidemiological, clinical, paraclinical, therapeutic, and evolutionary profile of patients with COVID-19 at Touba Ndamatou Public Hospital Hospital Establishment. Materials and Methods: This was a descriptive, retrospective, cross-sectional study of 114 cases hospitalized for COVID-19 at Touba Ndamatou Public Hospital Health Establishment, during the period from May 1, 2020, to September 30, 2021. Data were collected from patient medical records, entered using Epi Info Version 7 software, and analyzed using SSPS version 21.0 software. Results: The mean age of patients was 65 ± 14.5 years, with extremes of 25 and 92 years. The predominant age group was [46 - 65 years] with 39%. Males predominated with 65% (n = 74). The peak occurred in August 2021 with 57.8% of cases (n = 66). 68.15% of patients had at least one comorbidity, with hypertension and diabetes the most frequent comorbidities at 35.9% and 15.7% respectively. Dyspnea was the most frequent reason for consultation (70%), while the most common physical signs were pulmonary condensation syndrome (94%), respiratory distress (77%), and hypoxia (65%). Severe forms accounted for 32%. The most common CT images were ground-glass areas, predominantly in the basithoracic region. Azithromycin was used in all patients, oxygen therapy was used in 93%, and corticosteroids were used in 90%, although the average number of drugs taken per patient was eight (8). The average hospital stay was 4.54 days. The case fatality rate was 18.51% (n = 21). Advanced age (60 and over) and hypoxia were the main risk factors for mortality. Conclusion: The COVID-19 pandemic has been declared a global health emergency by the WHO. It has caused many deaths worldwide. Vaccination, the subject of much controversy in our context, would be the only means of preventing critical forms of the disease, especially among people at risk.
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