Introduction: Paraneoplastic Cushing’s syndrome is a condition representing a small-on average, a 10% fraction-of the cases of Cushing’s syndrome and affects 1% - 5% of patients with small-cell lung cancer. Case Presentation: We presented a patient with paraneoplastic Cushing’s syndrome due to small-cell lung cancer. Conclusion: This combination means a poorer prognosis with a shorter survival rate than other separate diagnoses.
References
[1]
Piasecka, M., Larsson, M., Papakokkinou, E., Olsson, L. and Ragnarsson, O. (2022) Is Ectopic Cushing’s Syndrome Underdi-agnosed in Patients with Small Cell Lung Cancer? Frontiers in Medicine, 9, Article ID: 954033. https://doi.org/10.3389/fmed.2022.954033
[2]
Chiboub, M., Kammoun, I., Gharbi, R., Kammoun, H., Bechiikh, M., Haouet, E., Margheli, A. and Kandara, H. (2021) Paraneoplastic Cushing’s Syndrome: A Diagnostic and Therapeutics Chal-lenge. A Case Report and Literature Review. Journal of Clinical Images and Medical Case Reports, 2, 1380.
[3]
Valassi, E., Franz, H., Brue, T., Feelders, R.A., Netea-Maier, R., Tsagarakis, S., et al. (2017) Diagnostic Tests for Cushing’s Syndrome Differ from Published Guidelines: Data from ERCUSYN. European Journal of Endocrinology, 176, 613-624. https://doi.org/10.1530/eje-16-0967
[4]
Mineur, L., Boustany, R. and Vazquez, L. (2021) Paraneoplastic Cushing Syn-drome in Gastrointestinal Neuroendocrine Tumour. Case Reports in Oncology, 14, 1407-1413. https://doi.org/10.1159/000518316
[5]
Zadrožna-Nowak, A., Debska-Szmich, S., Czernek, U., Krakowska, M. and Po-temski, P. (2016) Paraneoplastic Cushing’s Syndrome in a Patients with Small Cell Lung Cancer: Case Report. Oncology in Clinical Practice, 12, 215-217.
[6]
Richa, C.G., Saad, K.J., Halabi, G.H., Gharios, E.M., Nasr, F.L. and Merheb, M.T. (2018) Case-Series of Paraneoplastic Cushing Syndrome in Small-Cell Lung Cancer. Endocrinology, Diabetes & Metabolism Case Reports, 2018, 1-8. https://doi.org/10.1530/edm-18-0004
[7]
Nagy-Mignotte, H., Shestaeva, O., Vignoud, L., Guillem, P., Ruckly, S., Chabre, O., et al. (2014) Prognostic Impact of Paraneoplastic Cushing’s Syndrome in Small-Cell Lung Cancer. Journal of Thoracic Oncology, 9, 497-505. https://doi.org/10.1097/jto.0000000000000116
[8]
Sobin, L.H. (1881) The International Histological Classification of Tumours. Bulle-tin of the World Health Organisation, 59, 813-819.
[9]
Li, Y., Li, C., Qi, X., Yu, L. and Lin, L. (2023) Management of Small Cell Lung Cancer Complicated with Paraneoplastic Cushing’s Syn-drome: A Systematic Literature Review. Frontiers in Endocrinology, 14, Article ID: 1177125. https://doi.org/10.3389/fendo.2023.1177125
[10]
Snaith, J.R., Gao, B., Chipps, D. and Girgis, C.M. (2020) Massive Ad-renal Hyperplasia from Paraneoplastic Adrenocorticotropic Hormone. BMJ Case Reports, 13, e234892. https://doi.org/10.1136/bcr-2020-234892
[11]
Jeong, C., Lee, J., Ryu, S., Lee, H.Y., Shin, A.Y., Kim, J.S., et al. (2015) A Case of Ectopic Adrenocorticotropic Hormone Syndrome in Small Cell Lung Cancer. Tuberculosis and Respiratory Diseases, 78, 436-439. https://doi.org/10.4046/trd.2015.78.4.436
