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肠道菌群与胃肠道恶性肿瘤关系的研究进展
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Abstract:
肠道微生物群是人体微生物生态系统的重要组成部分，与宿主的免疫防御和代谢活动密切相关。近期研究显示，肠道微生物群与胃肠道癌症的发生发展有着复杂的相互作用。本文综合分析了肠道菌群与胃癌、结直肠癌之间的关系，探讨了菌群失衡如何影响肿瘤的发病机制，并评估了菌群调节在预防和治疗胃肠道肿瘤中的潜在应用。本综述旨在为深入理解胃肠道肿瘤的发病机制和开发新的防治策略提供科学依据。
The gut microbiota is an important component of the human microbial ecosystem and is closely related to the immune defense and metabolic activities of the host. Recent studies have shown complex interactions between the gut microbiota and the occurrence and development of gastrointestinal cancers. In this paper, we comprehensively analyzed the relationship between the intestinal flora and gastric cancer and colorectal cancer, explored how the flora imbalance affects the pathogenesis of tumors, and evaluated the potential application of flora regulation in the prevention and treatment of gastrointestinal tumors. This review aims to provide a scientific basis for deeply understanding the pathogenesis of gastrointestinal tumors and developing new prevention and control strategies.
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