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Health Risk Assessment of Exposure to Some Heavy Metals from Roasted Pork and Goat Meats Sold in Ishaka-Bushenyi Municipality, Uganda

DOI: 10.4236/jacen.2024.134022, PP. 325-340

Keywords: Heavy Metals, Roasted Meat, Health Risk Assessment, Contamination

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Abstract:

Heavy metals like iron (Fe), manganese (Mn), and copper (Cu) in trace levels are vital for human health as they support a number of physiological processes. In contrast, lead (Pb) and cadmium (Cd) provide no health benefits and can cause significant health problems when accumulated in the body. The main sources of heavy metal contamination in humans include the consumption of unhygienic and contaminated food products. In Uganda, roasted pork and goat meats are highly consumed among the population. Therefore, this research aims to determine the levels of Mn, Cu, Cd, Pb, and Fe and the associated human health risks in roasted pork and goat meat samples collected from Ishaka-Bushenyi Municipality, Uganda. Results showed that the mean levels of heavy metals (mg/kg) in roasted pork were in the order of Fe (4.706) > Pb (2.220) > Cu (1.927) > Cd (0.766) > Mn (0.391), while in roasted goat meat, the order was Pb (8.152) > Fe (5.152) > Cu (1.834) > Cd (0.794) > Mn (0.388). Lead (Pb) was observed to have the highest concentration which is likely to pose a risk to both children and adults, while manganese had the lowest concentration. The estimation of human health risks revealed that the essential metals had target hazard quotient (THQ) values below threshold in all samples while the non-essential elements had THQ values above 1. The hazard index (HI) obtained for each sample was greater than 1 indicating non-carcinogenic health risks to consumers (HI > 1). In 88% of cases, cancer risks (CR) values were within 104 and acceptable. Additionally, children are more vulnerable to non-cancer risks than the adults due to lower body weight. This research highlights the need of regularly monitoring of locations where vendors sell processed meats, as well as implementing laws to mitigate the health hazards associated with consuming polluted roasted meats.

References

[1]  Grace, D. (2015) Food Safety in Low-and Middle-Income Countries. International Journal of Environmental Research and Public Health, 12, 10490-10507.
[2]  Hoha, G.V., Costachescu, E., Leahu, A. and Pasarin, B. (2014) Heavy Metals Contamination Levels in Processed Meat Marketed in Romania. Environmental Engineering and Management Journal, 13, 2411-2415.
https://doi.org/10.30638/eemj.2014.269
[3]  Abd-Elghany, S.M., Mohammed, M.A., Abdelkhalek, A., Saad, F.S.S. and Sallam, K.I. (2020) Health Risk Assessment of Exposure to Heavy Metals from Sheep Meat and Offal in Kuwait. Journal of Food Protection, 83, 503-510.
https://doi.org/10.4315/0362-028x.jfp-19-265
[4]  Kamal, M.T., Al-Mamun, M., Hossain, M.M., Razzaque, M.A. and Hashem, M.A. (2022) Assessment of Pesticide Residues in Beef Feed and Meat in Bangladesh: A Safety Issues. Meat Research, 2, Article 21.
https://doi.org/10.55002/mr.2.3.21
[5]  Zahran, D.A. and Hendy, B.A. (2015 Heavy Metals and Trace Elements Composi-tion in Certain Meat and Meat Products Sold in Egyptian Markets. International Journal of Sciences: Basic and Applied Research, 20, 282-293.
http://gssrr.org/index.php?journal=JournalOfBasicAndApplied
[6]  EFSA (European Food Safety Authority) (2008) Mercury as Undesirable Substance in Animal Feed. Scientific Opinion of the Panel on Contaminants in the Food Chain. EFSA Journal, 6, 654.
[7]  EFSA (European Food Safety Authority) (2010) Scientific Opinion on Lead in Food. EFSA panel on contaminants in the food chain (CONTAM). EFSA Journal, 8, 1570.
https://doi.org/10.2903/j.efsa.2010.1570
[8]  Mohammadi, M.J., Yari, A.R., Saghazadeh, M., Sobhanardakani, S., Geravandi, S., Afkar, A., et al. (2017) A Health Risk Assessment of Heavy Metals in People Consuming Sohan in Qom, Iran. Toxin Reviews, 37, 278-286.
https://doi.org/10.1080/15569543.2017.1362655
[9]  Sobhanardakani, S., Tayebi, L. and Hosseini, S.V. (2017) Health Risk Assessment of Arsenic and Heavy Metals (Cd, Cu, Co, Pb, and Sn) through Consumption of Caviar of Acipenser Persicus from Southern Caspian Sea. Environmental Science and Pollution Research, 25, 2664-2671.
https://doi.org/10.1007/s11356-017-0705-8
[10]  Hosseini, S.V., Sobhanardakani, S., Tahergorabi, R. and Delfieh, P. (2013) Selected Heavy Metals Analysis of Persian Sturgeon’s (Acipenser persicus) Caviar from Southern Caspian Sea. Biological Trace Element Research, 154, 357-362.
https://doi.org/10.1007/s12011-013-9740-6
[11]  EFSA (European Food Safety Authority) (2004) Opinion of the Scientific Panel on Contaminants in Food Chain on a Request from the Commission Related to Cadmium as Undesirable Substance in Animal Feed. EFSA Journal, 2, 72.
[12]  Ogwok, P., Bamuwamye, M., Apili, G. and Musalima, J.H. (2014) Health Risk Posed by Lead, Copper and Iron via Consumption of Organ Meats in Kampala City (Uganda). Journal of Environment Pollution and Human Health, 2, 69-73.
[13]  Kasozi, K.I., Hamira, Y., Zirintunda, G., Alsharif, K.F., Altalbawy, F.M.A., Ekou, J., et al. (2021) Descriptive Analysis of Heavy Metals Content of Beef from Eastern Uganda and Their Safety for Public Consumption. Frontiers in Nutrition, 8, Article 592340.
https://doi.org/10.3389/fnut.2021.592340
[14]  Kasozi, K.I., Natabo, P.C., Namubiru, S., Tayebwa, D.S., Tamale, A. and Bamaiyi, P.H. (2018) Food Safety Analysis of Milk and Beef in Southwestern Uganda. Journal of Environmental and Public Health, 2018, Article ID: 1627180.
https://doi.org/10.1155/2018/1627180
[15]  Bamuwamye, M., Ogwok, P. and Tumuhairwe, V. (2015) Cancer and Non-Cancer Risks Associated with Heavy Metal Exposures from Street Foods: Evaluation of Roasted Meats in an Urban Setting. Journal of Environment Pollution and Human Health, 3, 24-30.
[16]  Alturiqi, A.S. and Albedair, L.A. (2012) Evaluation of Some Heavy Metals in Certain Fish, Meat and Meat Products in Saudi Arabian Markets. Egyptian Journal of Aquatic Research, 38, 45-49.
https://doi.org/10.1016/j.ejar.2012.08.003
[17]  Harmanescu, M., Alda, L.M., Bordean, D.M., Gogoasa, I. and Gergen, I. (2011) Heavy Metals Health Risk Assessment for Population via Consumption of Vegetables Grown in Old Mining Area; a Case Study: Banat County, Romania. Chemistry Central Journal, 5, Article No. 64.
https://doi.org/10.1186/1752-153x-5-64
[18]  U.S. EPA (U.S. Environmental Protection Agency) (2002). A Review of the Reference Dose and Reference Concentration Processes.
http://www.epa.gov/osa/review-reference-dose-and-reference-concentration-processes
[19]  Zeinali, T., Salmani, F. and Naseri, K. (2019) Dietary Intake of Cadmium, Chromium, Copper, Nickel, and Lead through the Consumption of Meat, Liver, and Kidney and Assessment of Human Health Risk in Birjand, Southeast of Iran. Biological Trace Element Research, 191, 338-347.
https://doi.org/10.1007/s12011-019-1637-6
[20]  Aendo, P., Mingkhwan, R., Senachai, K., Santativongchai, P., Thiendedsakul, P. and Tulayakul, P. (2021) Health Significant Alarms of Toxic Carcinogenic Risk Consumption of Blood Meal Metals Contamination in Poultry at a Gold Mining Neighborhood, Northern Thailand. Environmental Geochemistry and Health, 44, 783-797.
https://doi.org/10.1007/s10653-021-00971-6
[21]  Khanniri, E., Esmaeili, S., Akbari, M.E., Molaee-aghaee, E., Sohrabvandi, S., Akbari, N., et al. (2023) Determination of Heavy Metals in Municipal Water Network of Tehran, Iran: A Health Risk Assessment with a Focus on Carcinogenicity. International Journal of Cancer Management, 16, e137240.
https://doi.org/10.5812/ijcm-137240
[22]  Adzitey, F., Kumah, A. and Mensah, S.B.K. (2015) Assessment of the Presence of Selected Heavy Metals and Their Concentration Levels in Fresh and Grilled Beef/Guinea Fowl Meat in the Tamale Metropolis, Ghana. Research Journal of Environmental Sciences, 9, 152-158.
https://doi.org/10.3923/rjes.2015.152.158
[23]  Cabrera, M.C., Ramos, A., Saadoun, A. and Brito, G. (2010) Selenium, Copper, Zinc, Iron and Manganese Content of Seven Meat Cuts from Hereford and Braford Steers Fed Pasture in Uruguay. Meat Science, 84, 518-528.
https://doi.org/10.1016/j.meatsci.2009.10.007
[24]  Bilandžić, N., Sedak, M., Čalopek, B., Đokić, M., Varenina, I., Solomun Kolanović, B., et al. (2020) Evaluation of Element Concentrations in Beef and Pork Meat Cuts Available to the Population in the Croatian Capital. Foods, 9, Article 1861.
https://doi.org/10.3390/foods9121861
[25]  Balachandran, R.C., Mukhopadhyay, S., McBride, D., Veevers, J., Harrison, F.E., Aschner, M., et al. (2020) Brain Manganese and the Balance between Essential Roles and Neurotoxicity. Journal of Biological Chemistry, 295, 6312-6329.
https://doi.org/10.1074/jbc.rev119.009453
[26]  Wu, R., Yao, F., Li, X., Shi, C., Zang, X., Shu, X., et al. (2022) Manganese Pollution and Its Remediation: A Review of Biological Removal and Promising Combination Strategies. Microorganisms, 10, Article 2411.
https://doi.org/10.3390/microorganisms10122411
[27]  Nuapia, Y., Chimuka, L. and Cukrowska, E. (2018) Assessment of Heavy Metals in Raw Food Samples from Open Markets in Two African Cities. Chemosphere, 196, 339-346.
https://doi.org/10.1016/j.chemosphere.2017.12.134
[28]  Kasozi, K.I., Otim, E.O., Zirintunda, G., Tamale, A. and Otim, O. (2023) Multivariate Analysis of Heavy Metals Content of Beef from Soroti, Uganda. Toxicology Reports, 10, 400-408.
https://doi.org/10.1016/j.toxrep.2023.03.004
[29]  Oluwadamilare, K.Y., Adejoke, D.O., Oluwaseun, H.A. and Adejoke, B.A. (2023) Heavy Metals in Street-Roasted Food and Home-Oven-Roasted Foods. Journal of Science and Technology (Ghana), 41, 50-62.
[30]  Barone, A.M., Banovic, M., Asioli, D., Wallace, E., Ruiz-Capillas, C. and Grasso, S. (2021) The Usual Suspect: How to Co-Create Healthier Meat Products. Food Research International, 143, Article ID: 110304.
https://doi.org/10.1016/j.foodres.2021.110304
[31]  Scutarașu, E.C. and Trincă, L.C. (2023) Heavy Metals in Foods and Beverages: Global Situation, Health Risks and Reduction Methods. Foods, 12, Article 3340.
https://doi.org/10.3390/foods12183340
[32]  Bost, M., Houdart, S., Oberli, M., Kalonji, E., Huneau, J. and Margaritis, I. (2016) Dietary Copper and Human Health: Current Evidence and Unresolved Issues. Journal of Trace Elements in Medicine and Biology, 35, 107-115.
https://doi.org/10.1016/j.jtemb.2016.02.006
[33]  Wazir, S.M. and Ghobrial, I. (2017) Copper Deficiency, a New Triad: Anemia, Leucopenia, and Myeloneuropathy. Journal of Community Hospital Internal Medicine Perspectives, 7, 265-268.
https://doi.org/10.1080/20009666.2017.1351289
[34]  Collin, M.S., Venkatraman, S.K., Vijayakumar, N., Kanimozhi, V., Arbaaz, S.M., Stacey, R.G.S., et al. (2022) Bioaccumulation of Lead (Pb) and Its Effects on Human: A Review. Journal of Hazardous Materials Advances, 7, Article ID: 100094.
https://doi.org/10.1016/j.hazadv.2022.100094
[35]  Mghweno, L.R., Makokha, A.O., Magoha, H.S., Wekesa, J.M. and Nakajugo, A. (2008) Environmental Lead Pollution and Food Safety around Kampala City in Uganda. Journal of Applied Biosciences, 12, 642-649.
[36]  Cusick, S.E., Jaramillo, E.G., Moody, E.C., Ssemata, A.S., Bitwayi, D., Lund, T.C., et al. (2018) Assessment of Blood Levels of Heavy Metals Including Lead and Manganese in Healthy Children Living in the Katanga Settlement of Kampala, Uganda. BMC Public Health, 18, Article No. 717.
https://doi.org/10.1186/s12889-018-5589-0
[37]  Hassan Emami, M., Saberi, F., Mohammadzadeh, S., Fahim, A., Abdolvand, M., Ali Ehsan Dehkordi, S., et al. (2023) A Review of Heavy Metals Accumulation in Red Meat and Meat Products in the Middle East. Journal of Food Protection, 86, Article ID: 100048.
https://doi.org/10.1016/j.jfp.2023.100048
[38]  Piskin, E., Cianciosi, D., Gulec, S., Tomas, M. and Capanoglu, E. (2022) Iron Absorption: Factors, Limitations, and Improvement Methods. ACS Omega, 7, 20441-20456.
https://doi.org/10.1021/acsomega.2c01833
[39]  McDowell, L.A., Kudaravalli, P., Chen, R.J. and Sticco, K.L. (2024) Iron Overload. StatPearls.
[40]  Akhtar, S., Luqman, M., Farooq Awan, M.U., Saba, I., Khan, Z.I., Ahmad, K., et al. (2022) Health Risk Implications of Iron in Wastewater Soil-Food Crops Grown in the Vicinity of Peri Urban Areas of the District Sargodha. PLOS ONE, 17, e0275497.
https://doi.org/10.1371/journal.pone.0275497
[41]  Genchi, G., Sinicropi, M.S., Lauria, G., Carocci, A. and Catalano, A. (2020) The Effects of Cadmium Toxicity. International Journal of Environmental Research and Public Health, 17, Article 3782.
https://doi.org/10.3390/ijerph17113782
[42]  Tinkov, A.A., Filippini, T., Ajsuvakova, O.P., Skalnaya, M.G., Aaseth, J., Bjørklund, G., et al. (2018) Cadmium and Atherosclerosis: A Review of Toxicological Mechanisms and a Meta-Analysis of Epidemiologic Studies. Environmental Research, 162, 240-260.
https://doi.org/10.1016/j.envres.2018.01.008
[43]  Chowdhury, A.I. and Alam, M.R. (2024) Health Effects of Heavy Metals in Meat and Poultry Consumption in Noakhali, Bangladesh. Toxicology Reports, 12, 168-177.
https://doi.org/10.1016/j.toxrep.2024.01.008
[44]  Adejumo, O.E., Fasinu, P.S., Odion, J.E., Silva, B.O. and Fajemirokun, T.O. (2016) High Cadmium Levels in Cured Meat Products Marketed in Nigeria—Implications for Public Health. Asian Pacific Journal of Cancer Prevention, 17, 1933-1936.
https://doi.org/10.7314/apjcp.2016.17.4.1933
[45]  González-Weller, D., Karlsson, L., Caballero, A., Hernández, F., Gutiérrez, A., González-Iglesias, T., et al. (2006) Lead and Cadmium in Meat and Meat Products Consumed by the Population in Tenerife Island, Spain. Food Additives and Contaminants, 23, 757-763.
https://doi.org/10.1080/02652030600758142
[46]  USEPA (2011) Exposure Factors Handbook 2011 Edition (Final Report).
http://cfpub.epa.gov/ncea/risk/recordisplay.cfm?deid=236252
[47]  Kia, S.A., Aslani, R., Khaniki, G.J., Shariatifar, N. and Molaee-Aghaee, E. (2024) Determination and Health Risk Assessment of Heavy Metals in Chicken Meat and Edible Giblets in Tehran, Iran. Journal of Trace Elements and Minerals, 7, Article ID: 100117.
https://doi.org/10.1016/j.jtemin.2024.100117
[48]  Li, S. and Zhang, Q. (2010) Risk Assessment and Seasonal Variations of Dissolved Trace Elements and Heavy Metals in the Upper Han River, China. Journal of Hazardous Materials, 181, 1051-1058.
https://doi.org/10.1016/j.jhazmat.2010.05.120

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