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心肌桥与冠脉痉挛、血流动力学及MACE关系的研究进展
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Abstract:
越来越多的研究发现，心肌桥可能导致如左心室肥厚、心肌缺血、冠脉痉挛(CAS)、急性冠状动脉综合征、猝死等多种并发症。MB不仅是诱发CAS的重要风险因素，也是Ach试验阳性及MINOCA的独立预测因子，高龄、血脂异常和MB是男性和女性CAS (ACS还是CAD)的独立危险因素；MB会引起冠状动脉血流动力学的改变，有意义的冠状动脉血流动力学改变是MB导致各种并发症的主要原因；MB可能是MACE的独立预测因子，与心肌梗死似乎有直接关系。本文对MB与冠状动脉痉挛、冠状动脉血流动力学改变以及与MACE之间关系的最新研究进展进行了评述，对于心肌桥研究者及相关临床工作者具有一定的参考价值。
More and more studies have found that myocardial bridge may lead to multiple complications, such as left ventricular hypertrophy, myocardial ischemia, coronary spasm (CAS), acute coronary syndrome, sudden death, and so on. MB is not only an important risk factor for CAS, but also an independent predictor of Ach positive test and MINOCA. Old age, dyslipidemia and MB are independent risk factors for CAS (ACS or CAD) in men and women. MB can cause changes in coronary hemodynamics, and significant changes in coronary hemodynamics are the main cause of various complications caused by MB. MB may be an independent predictor of MACE and appears to be associated directly with myocardial infarction. In this review, the recent research progress on the relationship between MB and coronary spasm, changes in coronary hemodynamics, and MACE is reviewed, which has a certain reference value for myocardial bridge researchers and related clinical workers.
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