Single ventricle is an uncommon congenital cardiac pathology with high mortality at early ages. However, due to new strategies and timely surgical treatment, it is increasingly seen in adults, which has increased the survival rate. This condition is characterized by a heart with a single functional ventricular cavity. The aim of this article is to report the case of a 40-year-old male with single ventricle, who underwent several surgeries in his childhood. After these surgical procedures, the patient lost medical follow-up and presented complications derived from the disease itself. Heart Failure is a common complication in people with single ventricle, and pharmacological heart failure therapies have been ineffective in mitigating the need of the heart transplantation. That’s why it is essential to develop and apply new pharmacological techniques for the management of these patients in childhood as well as in adulthood. This would allow not only to avoid various comorbidities, but also to improve the quality of life of the patients.
References
[1]
Frescura, C. and Thiene, G. (2014) The New Concept of Univentricular Heart. FrontiersinPediatrics, 2, Article 62. https://doi.org/10.3389/fped.2014.00062
[2]
Herrera-Morales, J.A., Becerra-Gutiérrez, C.A., Cazares-Hernández, K.E. and Palomares-Alonso, V.I. (2023) Ventrículo único en adulto de 28 años de edad, historia y actualidad de un corazón no quirúrgico. CardiovascularandMetabolicScience, 34, 54-58. https://doi.org/10.35366/111547
[3]
Hager, A., Kaemmerer, H., Eicken, A., Fratz, S. and Hess, J. (2002) Long-term Survival of Patients with Univentricular Heart Not Treated Surgically. TheJournalofThoracicandCardiovascularSurgery, 123, 1214-1217. https://doi.org/10.1067/mtc.2002.122535
[4]
Garcia, A.M., Beatty, J. and Nakano, S.J. (2020) Heart Failure in Single Right Ventricle Congenital Heart Disease: Physiological and Molecular Considerations. AmericanJournalofPhysiology-HeartandCirculatoryPhysiology, 318, H947-H965. https://doi.org/10.1152/ajpheart.00518.2019
[5]
Pujol, C., Schiele, S., Maurer, S.J., Hock, J., Fritz, C., Hager, A., etal. (2020) Patients with Single-Ventricle Physiology over the Age of 40 Years. JournalofClinicalMedicine, 9, Article 4085. https://doi.org/10.3390/jcm9124085
[6]
Arnold, R. R., Loukanov, T. and Gorenflo, M. (2014). Hypoplastic Left Heart Syndrome-Unresolved Issues. Frontiers in Pediatrics, 2, Article 125. https://doi.org/10.3389/fped.2014.00125
[7]
Buber, J., Schwaegler, R.G. and Mazor Dray, E. (2019) Echocardiographic Evaluation of Univentricular Physiology and Cavopulmonary Shunts. Echocardiography, 36, 1381-1390. https://doi.org/10.1111/echo.14421
[8]
Osa, A., Almenar, L., Algarra, F., Palencia, M., Malo, P., García, A., etal. (1998) Trasplante cardíaco en el ventrículo único. RevistaEspañoladeCardiología, 51, 488-493. https://doi.org/10.1016/s0300-8932(98)74778-5
[9]
Nederend, M., Egorova, A.D., Vliegen, H.W., Roest, A.A.W., Ruijter, B.N., Korteweg, T., etal. (2022) Case Report of the Broad Spectrum of Late Complications in an Adult Patient with Univentricular Physiology Palliated by the Fontan Circulation. EuropeanHeartJournal—CaseReports, 6, ytac067. https://doi.org/10.1093/ehjcr/ytac067
[10]
Sachdeva, R., Valente, A.M., Armstrong, A.K., Cook, S.C., Han, B.K., Lopez, L., etal. (2020) ACC/AHA/ASE/HRS/ISACHD/SCAI/SCCT/SCMR/SOPE 2020 Appropriate Use Criteria for Multimodality Imaging during the Follow-Up Care of Patients with Congenital Heart Disease. JournaloftheAmericanCollegeofCardiology, 75, 657-703. https://doi.org/10.1016/j.jacc.2019.10.002
