针灸联合昂丹司琼片治疗胃肠肿瘤化疗患者胃肠道反应的效果观察
Observation on the Effect of Acupuncture Combined with Ondansetron Tablets in the Treatment of Gastrointestinal Response in Patients with Gastrointestinal Tumor Chemotherapy

目的：评价针灸联合昂丹司琼片的针药结合的治疗策略在胃肠肿瘤化疗患者胃肠道反应中的干预效果。方法：受试对象来自于我院2022年4月至2023年4月收治的80例胃肠肿瘤化疗患者，排除因颅内转移、胃肠道梗阻导致的中枢性呕吐或器质性病变性呕吐患者后，结合盲法分组原则将患者依次纳入对照组(n = 40，予以昂丹司琼治疗)与研究组(n = 40，实施针灸联合昂丹司琼治疗)，评价两组主要疗效、肝功能生化指标、安全性指标、营养状况。结果：较对照组，研究组患者症状积分水平更低(P < 0.05)，同时血清胆红素等肝功能生化指标水平更低(P < 0.05)，且血清白蛋白等营养状况指标水平更高(P < 0.05)，此外两组不良反应发生构成比比较无统计学意义(P > 0.05)。结论：中医针灸配合昂丹司琼片形成的针药结合的治疗策略在满足了胃肠肿瘤化疗患者对胃肠道反应治疗需求的同时，也兼顾了安全性，价值显著，疗效确切，具有积极的应用前景。
Objective: To evaluate the intervention efficacy of acupuncture combined with ondansetron tablets, a treatment strategy combining acupuncture and medicine, in the gastrointestinal response of patients with gastrointestinal tumor chemotherapy. Methods: Subjects were derived from 80 patients with gastrointestinal tumor chemotherapy admitted to our hospital from April 2022 to April 2023. After excluding patients with central vomiting due to intracranial metastasis, gastrointestinal obstruction, or vomiting due to organic lesions, patients were included in the control group (n = 40, ondansetron) and the study group (n = 40, acupuncture with ondansetron) in accordance with the principle of blinded grouping, to evaluate the main efficacy, biochemical index of liver function, safety index and nutritional status of the two groups. Results: Compared with the control group, the study group had a lower symptom score (P < 0.05), a lower biochemical level of liver function such as serum bilirubin (P < 0.05), and a higher level of nutritional status such as serum albumin (P < 0.05), and the composition ratio of adverse reactions was not statistically significant (P > 0.05). Conclusion: The treatment strategy of acupuncture and medicine formed by Chinese acupuncture and moxibustion and ondansetron tablets not only meets the needs of gastrointestinal tumor chemotherapy patients for the treatment of gastrointestinal response, but also takes into account the safety, with significant value and definite efficacy, and has a positive application prospect.