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玫瑰痤疮的中西医研究进展
Research Advances in Traditional Chinese and Western Medicine of Rosacea

DOI: 10.12677/tcm.2024.1310403, PP. 2703-2711

Keywords: 玫瑰痤疮,酒糟鼻,发病机制,中西医治疗,研究进展
Rosacea
, Acne Rosacea, Pathogenesis, Treatment of Traditional Chinese and Western Medicine, Research Progress

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Abstract:

玫瑰痤疮为临床常见难治性皮肤疾病,复发率高,不易根治,属于中医学“酒齄鼻”范畴。《诸病源候论·酒齄鼻侯》曰:“此为饮酒,热势冲面,而遇风冷之气相搏所生,故令鼻面生齄,赤疱匝匝然也。”这是一种影响面部中部的慢性损容性炎症疾病,女性更具易感性。其特征包括面部间歇性潮红、反复出现的红斑、伴有炎症的毛细血管扩张及丘疹、丘脓疱,重症患者可能遭遇鼻部外在形态改变或眼睛受损等问题,且常伴随焦虑、抑郁、偏头痛等症状。本研究主要叙述了玫瑰痤疮的病理机制及中西医疗法的运用。
Rosacea is also known as Acne Rosacea in traditional Chinese medicine. Women are more susceptible. It is a chronic disfiguring inflammatory disease which occurs in the middle of the face, presenting with paroxysmal flushing of the face, recurrent erythema, telangiectasia with inflammatory papules, papules and pustules. In severe cases, rhinophyma or eye damage may occur, etc. It is accompanied by symptoms such as anxiety, depression, migraine, and seborrheic alopecia, etc. This article reviews the pathogenesis of rosacea and treatment methods of traditional Chinese and Western medicine.

References

[1]  van Zuuren, E.J. (2017) Rosacea. New England Journal of Medicine, 377, 1754-1764.
https://doi.org/10.1056/nejmcp1506630
[2]  Wilkin, J., Dahl, M., Detmar, M., Drake, L., Feinstein, A., Odom, R., et al. (2002) Standard Classification of Rosacea: Report of the National Rosacea Society Expert Committee on the Classification and Staging of Rosacea. Journal of the American Academy of Dermatology, 46, 584-587.
https://doi.org/10.1067/mjd.2002.120625
[3]  王海棠, 主编. 中医美容学[M]. 北京: 中国中医药出版社出版, 2006.
[4]  Mc Aleer, M.A., Lacey, N. and Powell, F.C. (2009) The Pathophysiology of Rosacea. Italian Journal of Dermatology and Venereology, 144, 663-671.
[5]  Steinhoff, M., Schauber, J. and Leyden, J.J. (2013) New Insights into Rosacea Pathophysiology: A Review of Recent Findings. Journal of the American Academy of Dermatology, 69, S15-S26.
https://doi.org/10.1016/j.jaad.2013.04.045
[6]  Batycka-Baran, A., Hattinger, E., Marchenkov, A., Koziol, M., Bieniek, A., Szepietowski, J., et al. (2019) Koebnerisin (S100A15): A Novel Player in the Pathogenesis of Rosacea. Journal of the American Academy of Dermatology, 80, 1753-1755.
https://doi.org/10.1016/j.jaad.2018.06.012
[7]  Singh, A.K., McGoldrick, L.L. and Sobolevsky, A.I. (2018) Structure and Gating Mechanism of the Transient Receptor Potential Channel TRPV3. Nature Structural & Molecular Biology, 25, 805-813.
https://doi.org/10.1038/s41594-018-0108-7
[8]  范莉莉. ALA-光动力(ALA-PDT)治疗玫瑰痤疮疗效分析和基于TRPV1的抗炎机制研究[D]: [硕士学位论文]. 重庆: 陆军军医大学, 2019.
[9]  叶飞. 自拟清肺汤治疗酒糟鼻疗效观察[J]. 内蒙古中医药, 2013, 32(32): 10.
[10]  吴哲, 游友安. 清宁散加味治疗酒齄鼻129例[J]. 山西中医, 2001, 17(1): 25.
[11]  王俊. 除湿解毒汤治疗红斑痤疮的临床观察[D]: [硕士学位论文]. 沈阳: 辽宁中医药大学, 2007.
[12]  蔡善安, 黄玲妹. 加味清胃散治疗酒渣鼻30例疗效观察[J]. 中国中西医结合耳鼻咽喉科杂志, 1999(1): 49.
[13]  周宝宽. 辨证论治酒糟鼻经验[J]. 广西中医学院学报, 2011, 14(4): 15-16.
[14]  江颖. 酒渣鼻从肝论治[J]. 中医临床研究, 2013(19): 50-51.
[15]  孟繁静, 倪海洋. 边天羽在治疗气滞血瘀型酒糟鼻的经验[J]. 湖南中医杂志, 2018, 34(6): 44-55.
[16]  崔成军. 调情志法在玫瑰痤疮治疗中的应用[J]. 临床医药文献电子杂志, 2017, 4(91): 17832-17836.
[17]  田黎明, 柯丹, 彭圆, 等. 潜阳封髓丹加味治疗虚阳上浮型玫瑰痤疮疗效观察[J]. 中华中医药杂志, 2018, 33(2): 773-775.
[18]  张翠月. 中医药结合内外治疗方法对于酒糟鼻的疗效[J]. 中国实验方剂学杂志, 2011, 17(18): 266-267.
[19]  林云祥. 百部醇浸液外用治疗酒糟鼻21例[J]. 中医外治杂志, 2010, 19(3): 21.
[20]  郭喜利, 王敏, 胡政, 等. 关于火针疗法作用机制的研究探讨[J]. 光明中医, 2016, 31(5): 683-685.
[21]  周建英, 李梦, 朱林林, 等. 火针效应机制及其在临床实践中的应用概览[J]. 辽宁中医药大学学报, 2016, 18(7): 86-88.
[22]  周盈盈. 毫火针联合消风清肺散治疗红斑毛细血管扩张型玫瑰痤疮(肺经风热证)的临床疗效观察[D]: [硕士学位论文]. 成都: 成都中医药大学, 2022.
[23]  丁相竹. 耳穴揿针联合五味消毒饮加减治疗丘疹脓疱型玫瑰痤疮(热毒蕴肤证)的疗效观察[D]: [硕士学位论文]. 成都: 成都中医药大学,2022.
[24]  Layton, A.M., Schaller, M., Homey, B., Hofmann, M.A., Bewley, A.P., Lehmann, P., et al. (2015) Brimonidine Gel 0.33% Rapidly Improves Patient‐Reported Outcomes by Controlling Facial Erythema of Rosacea: A Randomized, Double‐Blind, Vehicle‐Controlled Study. Journal of the European Academy of Dermatology and Venereology, 29, 2405-2410.
https://doi.org/10.1111/jdv.13305
[25]  Draelos, Z.D., Gold, M.H., Weiss, R.A., Baumann, L., Grekin, S.K., Robinson, D.M., et al. (2018) Efficacy and Safety of Oxymetazoline Cream 1.0% for Treatment of Persistent Facial Erythema Associated with Rosacea: Findings from the 52-Week Open Label REVEAL Trial. Journal of the American Academy of Dermatology, 78, 1156-1163.
https://doi.org/10.1016/j.jaad.2018.01.027
[26]  Docherty, J.R., Steinhoff, M., Lorton, D., Detmar, M., Schäfer, G., Holmes, A., et al. (2016) Multidisciplinary Consideration of Potential Pathophysiologic Mechanisms of Paradoxical Erythema with Topical Brimonidine Therapy. Advances in Therapy, 33, 1885-1895.
https://doi.org/10.1007/s12325-016-0404-8
[27]  Zuuren, E.J., Fedorowicz, Z., Tan, J., Linden, M.M.D., Arents, B.W.M., Carter, B., et al. (2019) Interventions for Rosacea Based on the Phenotype Approach: An Updated Systematic Review Including GRADE Assessments. British Journal of Dermatology, 181, 65-79.
https://doi.org/10.1111/bjd.17590
[28]  Marson, J.W. and Baldwin, H.E. (2019) Rosacea: A Wholistic Review and Update from Pathogenesis to Diagnosis and Therapy. International Journal of Dermatology, 59, e175-e182.
https://doi.org/10.1111/ijd.14757
[29]  Del, R.J., Schlessinger, J. and Werschler, P. (2008) Comparison of Anti-Inflammatory Dose Doxycycline versus Doxycycline 100 mg in the Treatment of Rosacea. Journal of Drugs in Dermatology, 7, 573-576.
https://pubmed.ncbi.nlm.nih.gov/18561589/
[30]  Akhyani, M., Ehsani, A.H., Ghiasi, M. and Jafari, A.K. (2008) Comparison of Efficacy of Azithromycin Vs. Doxycycline in the Treatment of Rosacea: A Randomized Open Clinical Trial. International Journal of Dermatology, 47, 284-288.
https://doi.org/10.1111/j.1365-4632.2008.03445.x
[31]  Gollnick, H., Blume‐Peytavi, U., Szabó, E.L., Meyer, K., Hauptmann, P., Popp, G., et al. (2010) Systemic Isotretinoin in the Treatment of Rosacea—Doxycycline‐ and Placebo‐Controlled, Randomized Clinical Study. JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 8, 505-514.
https://doi.org/10.1111/j.1610-0387.2010.07345.x
[32]  Seo, K.Y., Kang, S.M., Ha, D.Y., Chin, H.S. and Jung, J.W. (2018) Long-Term Effects of Intense Pulsed Light Treatment on the Ocular Surface in Patients with Rosacea-Associated Meibomian Gland Dysfunction. Contact Lens and Anterior Eye, 41, 430-435.
https://doi.org/10.1016/j.clae.2018.06.002
[33]  Alam, M., Voravutinon, N., Warycha, M., Whiting, D., Nodzenski, M., Yoo, S., et al. (2013) Comparative Effectiveness of Nonpurpuragenic 595-Nm Pulsed Dye Laser and Microsecond 1064-Nm Neodymium:yttrium-Aluminum-Garnet Laser for Treatment of Diffuse Facial Erythema: A Double-Blind Randomized Controlled Trial. Journal of the American Academy of Dermatology, 69, 438-443.
https://doi.org/10.1016/j.jaad.2013.04.015
[34]  贾婕, 张荣, 鲁东平, 等. 精准脉冲光联合长脉冲1064 nm Nd: YAG激光治疗玫瑰痤疮的疗效观察[J]. 中国皮肤性病学杂志, 2021, 35(12): 1359-1364.
[35]  马涛, 吕明军. 二氧化碳点阵激光联合玫芦消痤膏治疗玫瑰痤疮的疗效观察[J]. 贵州医药, 2023, 47(3): 399-401.
[36]  Kim, M.J., Kim, J.H., Cheon, H.I., Hur, M.S., Han, S.H., Lee, Y.W., et al. (2019) Assessment of Skin Physiology Change and Safety after Intradermal Injections with Botulinum Toxin: A Randomized, Double-Blind, Placebo-Controlled, Split-Face Pilot Study in Rosacea Patients with Facial Erythema. Dermatologic Surgery, 45, 1155-1162.
https://doi.org/10.1097/dss.0000000000001819
[37]  Park, K.Y., Hyun, M.Y., Jeong, S.Y., Kim, B.J., Kim, M.N. and Hong, C.K. (2015) Botulinum Toxin for the Treatment of Refractory Erythema and Flushing of Rosacea. Dermatology, 230, 299-301.
https://doi.org/10.1159/000368773
[38]  Bharti, J., Sonthalia, S. and Jakhar, D. (2023) Mesotherapy with Botulinum Toxin for the Treatment of Refractory Vascular and Papulopustular Rosacea. Journal of the American Academy of Dermatology, 88, e295-e296.
https://doi.org/10.1016/j.jaad.2018.05.014
[39]  Dayan, S.H., Ashourian, N. and Cho, K. (2017) A Pilot, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of IncobotulinumtoxinA Injections in the Treatment of Rosacea. Journal of Drugs in Dermatology, 16, 549-554.
https://pubmed.ncbi.nlm.nih.gov/28686772/
[40]  Fan, L., Yin, R., Lan, T. and Hamblin, M.R. (2018) Photodynamic Therapy for Rosacea in Chinese Patients. Photodiagnosis and Photodynamic Therapy, 24, 82-87.
https://doi.org/10.1016/j.pdpdt.2018.08.005
[41]  Sun, Y., Chen, L., Zhang, Y., Gao, X., Wu, Y. and Chen, H. (2018) Topical Photodynamic Therapy with 5-Aminolevulinic Acid in Chinese Patients with Rosacea. Journal of Cosmetic and Laser Therapy, 21, 196-200.
https://doi.org/10.1080/14764172.2018.1502455
[42]  Bao, N., Gu, T., Zeng, J., Wu, Y., Sun, Y., Gao, X., et al. (2022) Combined Therapy of 5-Aminolevulinic Acid Photodynamic Therapy and Intense Pulsed Light for Rosacea. Lasers in Medical Science, 38, Article No. 17.
https://doi.org/10.1007/s10103-022-03685-y
[43]  刘景桢, 刘淮. 玫瑰痤疮的药物治疗[J]. 皮肤病与性病, 2017, 39(2): 95-96.
[44]  徐劲, 乔丽, 罗卫. 米诺环素联合化瘀祛斑胶囊治疗玫瑰痤疮的疗效观察[J]. 武警医学, 2015(11): 1108-1110.
[45]  毕良华. 加味逍遥散联合盐酸米诺环素治疗玫瑰痤疮疗效的观测研究[J]. 临床医药文献电子杂志, 2016, 3(37): 7440-7441.
[46]  万远芳, 柯丹, 陶春蓉. 凉血清肺散联合米诺环素治疗玫瑰痤疮的临床疗效[J]. 医学综述, 2017, 23(4): 802-804,809.
[47]  赵梓刚, 李承新. 玫瑰痤疮非药物疗法[J]. 皮肤病与性病, 2017, 39(2): 96-98.
[48]  曹洋, 杨岚, 周冬梅, 等. 颠倒散联合双波长激光疗法在肺胃热盛型玫瑰痤疮患者中的临床观察[J]. 北京中医药2018, 37(6): 513-518.
[49]  吴翘. 枇清饮联合595nm脉冲染料激光治疗肺胃蕴热证玫瑰痤疮的临床研究[D]: [硕士学位论文]. 昆明: 云南中医药大学, 2021.
[50]  于东涛. 三子颗粒联合脉冲激光治疗酒糟鼻临床疗效观察[J]. 基层医学论坛, 2016, 20(18): 2461-2463.
[51]  朱云霞, 陈福强, 孔凡楼. 润燥止痒胶囊联合超声聚焦技术在玫瑰痤疮临床治疗中的应用效果[J]. 新中医, 2016(9): 88-89.
[52]  罗丽娜, 刘利红, 张静, 等. 红蓝光与中药面膜联合疗法对玫瑰痤疮的临床疗效观察[J]. 湖南中医药大学学报, 2017, 37(12): 1400-1403.
[53]  亚来群, 刘宝咸, 张永梅. 中药合并激光治疗与术后护理对I期酒渣鼻患者影响的临床研究[J]. 现代中医药, 2016(6): 67-69.
[54]  叶舒颖. 三仁凉血汤联合595 nm激光治疗玫瑰痤疮的临床疗效观察[D]: [硕士学位论文]. 昆明: 云南中医药大学, 2021.

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