启宫夺命汤联合西药治疗多囊卵巢综合征的临床疗效观察
Observation on the Clinical Effect of Qigong Duoming Decoction Combined with Western Medicine in the Treatment of Polycystic Ovary Syndrome

目的：为了研究启宫夺命汤联合西药治疗多囊卵巢综合征的临床疗效，进一步探究其机制，提高患者满意度。方法：选择2022年3月份至2023年10月份在遵义市中医院妇科门诊及住院部收治的60名患者，1~30号为对照组，31~60号为观察组，两组分别为30人，对照组予饭后口服二甲双胍缓释片，每次0.5 g，每天两次；每天睡前口服达英-35，每次一片，每天一次；观察组患者在对照组的基础上使用启宫夺命汤(川芎、麸炒白术、半夏、香附、茯苓、神曲、化橘红、炙甘草、桂枝、桃仁、赤芍、牡丹皮)。评估两组病人在治疗前与治疗后的各项指标(E2、SHBG、AMH、LH)水平判断分析药物取得的临床疗效。结果：治疗后两组均可以使E2、SHBG水平提高，AMH、LH水平降低，组内比较有差异(P < 0.05)，与对照组相比，观察组在降低AMH上疗效更显著，提高E2水平幅度更大(P < 0.05)，余性激素指标无差异(P > 0.05)。结论：启宫夺命汤联合西药治疗多囊卵巢综合征进行治疗，能够使E2、SHBG水平提高，AMH、LH水平降低，能明显地缓解病人的临床症状，改善预后，提升生活质量，值得广泛应用。
Objective: In order to study the clinical efficacy of Qigong Duoming Decoction combined with Western medicine in the treatment of Polycystic Ovary Syndrome, further explore the mechanism and improve patient satisfaction. Methods: 60 patients treated in the gynecology outpatient and inpatient departments of Zunyi Traditional Chinese Medicine Hospital from March 2022 to October 2023 were selected. Numbers 1 to 30 were assigned to the control group, and numbers 31 to 60 were assigned to the observation group, with 30 people in each group. The control group received oral metformin su tained-release tablets after meals, 0.5 g each time, twice a day; and Diane-35, one tablet, once a day before going to bed. The observation group was treated with Qigong Duoming Decoction (consisting of Chuanxiong, oven-fried Atractylodes, Pinellia ternata, Cyperus rotundus L., Poria, Shenqu, Citri Reticulatae Pericarpium, roasted licorice, cinnamon twig, peach kernel, red peony root, and moutan bark) on top of the control group’s treatment. To evaluate the clinical efficacy of the indicators (E2, SHBG, AMH, LH) before and after treatment in the two groups. Results: After treatment, both groups could increase E2 and SHBG, AMH and LH, and differ within the groups (P < 0.05). Compared with the control group, the observation group was more effective in reducing AMH, and the E2 level was greater (P < 0.05), with no difference in residual hormone index (P > 0.05). Conclusion: The treatment of polycystic ovary syndrome combined with Western medicine can improve the level of E2 and SHBG, reduce the level of AMH and LH, which can significantly relieve the clinical symptoms of patients, improve the prognosis and improve the quality of life, which is worth widely used.