|
一例嗜铬细胞瘤切除术中顽固性低血压的处理
|
Abstract:
患者,女,67岁,体重56 kg,因高血压病史7年,伴阵发性心悸、头晕、头痛,加重2个月入院。术前诊断:1、左侧腹膜后肿瘤:异位嗜铬细胞瘤?2、高血压病3级很高危。术前降压扩容后,拟在全麻下行腹腔镜下左侧腹膜后肿瘤切除术。术中瘤体切除前循环波动较小,并充分扩容,瘤体切除后患者出现顽固性低血压,经大剂量血管活性药以及快速大量补液升压效果均不明显,后给予补充糖皮质激素、亚甲蓝、血管加压素、调整体位、低温,以及减浅麻醉调整内环境的稳定,维持重要脏器的灌注,血压回升。术后患者预后良好。
A female patient, 67 years old, weighing 56 kg, was admitted to hospital with a 7-year history of hypertension, accompanied by paroxysmal heart palpitations, dizziness, and headache, which worsened for 2 months. Preoperative diagnosis: 1. Left retroperitoneal tumor: ectopic pheochromocytoma? 2. Hypertension level 3 is very high risk. After preoperative hypotension and volume expansion, laparoscopic left retroperitoneal tumor resection was planned under general anesthesia. During the operation, the circulation fluctuation before tumor resection was small, and the volume was fully expanded. After tumor resection, the patient had intractable hypotension, and the effect of high-dose vasoactive drugs and rapid and massive fluid infusion was not obvious. After that, the patients were given glucocorticoid, methylene blue, vasopressin, posture adjustment, hypothermia, and shallow anesthesia to adjust the stability of the internal environment, maintain the perfusion of important organs, and the blood pressure rose. The prognosis was good.
[1] | 李明阳, 杜昕, 毕然, 等. 肾上腺混合性嗜铬细胞瘤一例[J]. 中华医学杂志, 2017, 97(26): 2065-2066. |
[2] | 李汉忠, 邓建华. 复杂嗜铬细胞瘤临床诊治的关键问题[J]. 中华泌尿外科杂志, 2018, 39(5): 325-328. |
[3] | Lenders, J.W.M., Duh, Q., Eisenhofer, G., Gimenez-Roqueplo, A., Grebe, S.K.G., Murad, M.H., et al. (2014) Pheochromocytoma and Paraganglioma: An Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology & Metabolism, 99, 1915-1942. https://doi.org/10.1210/jc.2014-1498 |
[4] | 黄杰, 余闫宏, 张德清, 徐万超, 杨敏, 邹岷, 肖民辉. 48例后腹腔镜手术治疗肾上腺嗜铬细胞瘤的临床研究[J]. 重庆医学, 2015, 44(21): 2933-2934. |
[5] | 闵祥振, 贾智勇, 郭蕊, 等. 近红外光谱脑氧饱和度监测的临床应用进展[J]. 临床麻醉学杂志, 2020, 36(3): 307-310. |
[6] | 万冬丽, 周权, 黄玉琴, 黄强, 鞠涛, 徐化强. 嗜铬细胞瘤危象1例及文献复习[J]. 湖北医药学院学报, 2023, 42(3): 308-311. |
[7] | 张羽冠, 汪一, 徐宵寒, 等. 嗜铬细胞瘤切除术全身麻醉围术期血流动力学管理[J]. 临床麻醉学杂志, 2019, 35(8): 818-820. |
[8] | 王阿倩, 苏红玲, 蒋凯煜, 周明方, 苏新, 段一超, 黄晏, 朱岩, 曹云山. 电解质紊乱与心律失常[J]. 实用心电学杂志, 2019, 28(2): 120-126. |
[9] | 俞莹, 黄巧文, 翁险峰, 张良成, 彭勇刚. 血管麻痹综合征的潜在治疗靶点: 氧自由基[J]. 麻醉安全与质控, 2020, 4(6): 321-326. |
[10] | 林华, 郑瑞, 陈齐红, 等. 不同时机使用小剂量氢化可的松治疗感染性休克的效果比较[J]. 实用临床医药杂志, 2016, 20(24): 107-108. |
[11] | 张建, 任宏, 等. 重症超声指导以改善脑灌注为目标的一例儿童顽固性血管麻痹性休克的治疗[J]. 中国小儿急救医学, 2021, 28(4): 278-282. |
[12] | 吕文远, 汤文喜, 等. 亚甲蓝在血管麻痹综合征中的作用[J]. 国际麻醉学与复苏杂志, 2020, 41(10): 991-995. |
[13] | 孔昊, 王东信. 嗜铬细胞瘤患者的围术期管理[J]. 临床麻醉学杂志, 2017, 33(11): 1132-1136. |