Background: Bronchiectasis, characterized by irreversible bronchial dilation, often affects patients’ long-term health. This study assessed the prevalence and risk factors of bronchiectasis in adults based on CT scan-finding department (OPD) patients in a single center. Methods: We retrospectively reviewed the medical records of 301 adult OPD patients examined between 2021 and 2022. We diagnosed bronchiectasis based on high-resolution chest CT scans. We analyzed demographic characteristics, tuberculosis (TB) history, and the presence of comorbid conditions using electronic medical records. We conducted univariate and multivariate analyses to identify potential risk factors for bronchiectasis. Results: Among 301 patients who had high-resolution chest CT scans, 139 (46.1%) received a diagnosis of bronchiectasis. Multivariable analysis revealed significant associations between bronchiectasis and the following factors: age greater than 50 years and history of tuberculosis. We found no significant correlation between gender and smoking history. Conclusion: This study found a high prevalence of bronchiectasis (46.1%) among OPD patients in our single center, with older age and a history of tuberculosis identified as independent risk factors.
References
[1]
Chalmers, J.D., Aliberti, S. and Blasi, F. (2015) Management of Bronchiectasis in Adults. European Respiratory Journal, 45, 1446-1462. https://doi.org/10.1183/09031936.00119114
[2]
Lin, J., Xu, J. and Qu, J. (2016) Bronchiectasis in China. Annals of the American Thoracic Society, 13, 609-616. https://doi.org/10.1513/annalsats.201511-740ps
[3]
Sanchez-Carpintero Abad, M., Sanchez-Salcedo, P., de-Torres, J.P., Alcaide, A.B., Seijo, L.M., Pueyo, J., et al. (2020) Prevalence and Burden of Bronchiectasis in a Lung Cancer Screening Program. PLOS ONE, 15, e0231204. https://doi.org/10.1371/journal.pone.0231204
[4]
Martin, C., Thevenot, G., Danel, S., Chapron, J., Tazi, A., Macey, J., et al. (2011) Pseudomonas Aeruginosa Induces Vascular Endothelial Growth Factor Synthesis in Airway Epithelium in Vitro and in Vivo. European Respiratory Journal, 38, 939-946. https://doi.org/10.1183/09031936.00134910
[5]
De la Rosa, D., Martínez-Garcia, M., Olveira, C., Girón, R., Máiz, L. and Prados, C. (2016) Annual Direct Medical Costs of Bronchiectasis Treatment. Chronic Respiratory Disease, 13, 361-371. https://doi.org/10.1177/1479972316643698
[6]
Ringshausen, F.C., de Roux, A., Pletz, M.W., Hämäläinen, N., Welte, T. and Rademacher, J. (2013) Bronchiectasis-Associated Hospitalizations in Germany, 2005-2011: A Population-Based Study of Disease Burden and Trends. PLOS ONE, 8, e71109. https://doi.org/10.1371/journal.pone.0071109
[7]
Seitz, A.E., Olivier, K.N., Adjemian, J., Holland, S.M. and Prevots, D.R. (2012) Trends in Bronchiectasis among Medicare Beneficiaries in the United States, 2000 to 2007. Chest, 142, 432-439. https://doi.org/10.1378/chest.11-2209
[8]
Goolam-Mahomed, A., Maasdorp, S.D., Barnes, R., Van Aswegen, H., Lupton-Smith, A., Allwood, B., et al. (2023) South African Thoracic Society Position Statement on the Management of Non-Cystic Fibrosis Bronchiectasis in Adults: 2023. African Journal of Thoracic and Critical Care Medicine, 29, 71-80. https://doi.org/10.7196/ajtccm.2023.v29i2.647
[9]
Binegdie, A.B., Brenac, S., Devereux, G., Meme, H., El Sony, A., Gebremariam, T.H., et al. (2022) Post-Tb Lung Disease in Three African Countries. The International Journal of Tuberculosis and Lung Disease, 26, 891-893. https://doi.org/10.5588/ijtld.22.0261
[10]
Dhar, R., Singh, S., Talwar, D., Murali Mohan, B.V., Tripathi, S.K., Swarnakar, R., et al. (2023) Clinical Outcomes of Bronchiectasis in India: Data from the EMBARC/Respiratory Research Network of India Registry. European Respiratory Journal, 61, Article 2200611.
[11]
Karataş, M., Dirie, A., Çolakoğlu, S., Hussein, A. and Ali, A. (2024) Tuberculosis Treatment Outcomes and Associated Factors in Benadir Somalia. A Multicenter Cohort Study. International Journal of General Medicine, 17, 2711-2718. https://doi.org/10.2147/ijgm.s463237
[12]
Titus, G., Hassanali, S. and Feldman, C. (2023) Non-Cystic Fibrosis Bronchiectasis: A Single-Centre Retrospective Study in Johannesburg, South Africa. African Journal of Thoracic and Critical Care Medicine, 29, e1017. https://doi.org/10.7196/ajtccm.2023.v29i4.1017
[13]
Dirie, A.M.H., Çolakoğlu, S., Abdi, B.M., Shire, A.M. and Abdinur, A.H. (2022) The Prevalence of HIV among Tuberculosis Patients in Benadir, Somalia. Retrospective Multi-Center Study. Annals of Medicine & Surgery, 78. https://doi.org/10.1016/j.amsu.2022.103793
[14]
Quint, J.K., Millett, E.R.C., Joshi, M., Navaratnam, V., Thomas, S.L., Hurst, J.R., et al. (2015) Changes in the Incidence, Prevalence and Mortality of Bronchiectasis in the UK from 2004 to 2013: A Population-Based Cohort Study. European Respiratory Journal, 47, 186-193. https://doi.org/10.1183/13993003.01033-2015
[15]
Dhar, R., Singh, S., Talwar, D., Mohan, M., Tripathi, S.K., Swarnakar, R., et al. (2019) Bronchiectasis in India: Results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry. Lancet Glob Health, 7, e1269-e1279.
[16]
Monteagudo, M., Rodríguez-Blanco, T., Barrecheguren, M., Simonet, P. and Miravitlles, M. (2016) Prevalence and Incidence of Bronchiectasis in Catalonia, Spain: A Population-Based Study. Respiratory Medicine, 121, 26-31. https://doi.org/10.1016/j.rmed.2016.10.014
[17]
Martínez-García, M.Á., Soler-Cataluña, J.J., Donat Sanz, Y., Catalán Serra, P., Agramunt Lerma, M., Ballestín Vicente, J., et al. (2011) Factors Associated with Bronchiectasis in Patients with COPD. Chest, 140, 1130-1137. https://doi.org/10.1378/chest.10-1758
[18]
King, P.T., Holdsworth, S.R., Freezer, N.J., Villanueva, E. and Holmes, P.W. (2006) Characterisation of the Onset and Presenting Clinical Features of Adult Bronchiectasis. Respiratory Medicine, 100, 2183-2189. https://doi.org/10.1016/j.rmed.2006.03.012
