中医民族医药治疗肝纤维化的研究进展
Research Progress in the Treatment of Liver Fibrosis with Traditional Chinese Medicine and Ethnic Medicine

肝纤维化是指在多种情况的作用下发生肝脏组织的损伤及修复，其中包括非酒精性脂肪性肝炎、酒精性脂肪性肝炎、酒精性脂肪性肝炎、与病毒有关的慢性肝炎、自身免疫性和遗传性肝脏疾病等。肝纤维化是慢性肝病发展三部曲的重要环节，该过程的发生发展促使肝病向肝硬化及肝癌的病理转变，若未得到有效干预，极易发展为肝硬化(诱发食管胃底静脉曲张破裂出血、肝性脑病、腹水等严重并发症)，甚至转变为肝癌，严重影响患者的生活质量，因此早期积极有效的干预尤为重要。肝纤维化的重点在于防治，这一治疗思路符合中医“未病先防”的理念。逆转或控制纤维化的发生发展是患者治疗的最终目标。由于现代医学治疗尚未达到治疗的理想目标，近年来我国越来越重视从中医民族医药宝库中挖掘其优势，而民族医药治疗在一方面凸显出了中医药的优势，在临床疗效的基础上，基础实验研究取得了一定的进展，为肝纤维化的治疗开拓了新的领域。
Liver fibrosis refers to the damage and repair of liver tissue under the influence of various conditions, including non-alcoholic fatty hepatitis, alcoholic fatty hepatitis, alcoholic fatty hepatitis, viral-related chronic hepatitis, autoimmune and hereditary liver diseases, etc. Liver fibrosis is an important part of the trilogy of chronic liver disease development. The occurrence and development of this process promote the pathological transformation of liver disease to cirrhosis and liver cancer. If it is not effectively intervened, it is very easy to develop into cirrhosis (inducing serious complications such as esophageal varicose bleeding, hepatic encephalopathy, ascites, etc.) or even into liver cancer, which seriously affects the quality of life of patients. Therefore, early active and effective intervention is particularly important. The focus of liver fibrosis is prevention and treatment. This treatment idea is in line with the concept of “prevention before illness” in traditional Chinese medicine. Reversing or controlling the occurrence and development of fibrosis is the ultimate goal of patient treatment. Since modern medical treatment has not yet achieved the ideal goal of treatment, my country has paid more and more attention to exploring its advantages from the treasure house of traditional Chinese medicine in recent years. On the one hand, ethnic medicine treatment highlights the advantages of traditional Chinese medicine. On the basis of clinical efficacy, basic experimental research has made certain progress, opening up new areas for the treatment of liver fibrosis.