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盆腔内静脉内平滑肌瘤病理报告1例
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Abstract:
目的:了解盆腔静脉内平滑肌瘤(Intrapelvic Venous Leiomyoma, IVL)的临床特点,鉴别诊断和治疗方法。方法:回顾性分析我院2024年1月住院手术并经病理证实的1例静脉内平滑肌瘤病例。结果:患者以“腹痛5天,加重半天”之主诉入院。于我院行腹腔镜下盆腔粘连松解 + 全子宫双附件切除术。取标本送病理检查,病理诊断:考虑静脉内平滑肌瘤(病理号:24-00729)妇科B超示:宫颈肥大,回声不均匀(5.2 × 4.6 cm)。术后切口愈合良好。结论:静脉内平滑肌瘤是一类罕见的妇科良性肿瘤,大多数为隐匿性起病,IVL的镜下组织结构与子宫肿瘤类似,临床上往往被误诊、漏诊,因此,对子宫肌瘤或子宫肌瘤手术史的患者,出现盆腔包块、阴道壁肿物、下腔静脉或心腔内肿物时,均应考虑本病的可能性,一旦发现应尽早手术切除,避免其继续进展。
To understand the clinical characteristics, differential diagnosis and treatment of leiomyoma in the pelvic vein. Method: Retrospective analysis of our institute A case of intravenous leiomyoma confirmed by hospitalization in January 2024. Results: The patient was admitted to the hospital with “abdominal pain for 5 days, aggravated for half a day”. Laparoscopic pelvic adhesion loosening + total uterine double accessory resection was performed in our hospital. Take specimens and send them for pathological examination, pathological diagnosis: consider intravenous leiomyoma (pathological number: 24-00729). B-ultrasound: cervical hypertrophy, uneven echo (5.2 × 4.6 cm). The postoperative incision heals well. Conclusion: Intravenous leiomyoma is a rare gynecological benign tumor, most of which are occult onset. The microscopic tissue structure of IVL is similar to that of uterine tumors. Clinically, it is often misdiagnosed and missed. Therefore, for patients with a history of surgery for uterine fibroids or uterine fibroids, there are pelvic mass, wall tumors, inferior vena cava or heart. When there is a tumor in the cavity, the possibility of the disease should be considered. Once it is found, it should be surgically removed as soon as possible to avoid its continued development.
[1] | 郭建华, 高新茹, 刘萌萌, 袁鹏, 盛长青, 张婧婧, 苏雪, 高彬. 局限于盆腔的子宫静脉内平滑肌瘤病1例及文献复习[J]. 空军军医大学学报, 2024: 1-5. |
[2] | Yu, X., Fu, J., Cao, T., Huang, L., Qie, M. and Ouyang, Y. (2021) Clinicopathologic Features and Clinical Outcomes of Intravenous Leiomyomatosis of the Uterus: A Case Series. Medicine, 100, e24228. https://doi.org/10.1097/md.0000000000024228 |
[3] | 夏星璐, 李娟清, 林俊. 病灶局限在盆腔的静脉平滑肌瘤病81例临床分析[J]. 中华妇产科杂志, 2022, 57(1): 39-45. |
[4] | 许阡, 王欣. 子宫静脉内平滑肌瘤病的诊治进展[J]. 国际妇产科学杂志, 2022, 49(6): 616-620. |
[5] | Deng, Y. and Song, B. (2020) Three Case Reports of Intravenous Leiomyomatosis with Intracardiac Extensions. The Thoracic and Cardiovascular Surgeon Reports, 9, e40-e43. https://doi.org/10.1055/s-0040-1715183 |
[6] | Boavida Ferreira, J., Cabrera, R., Santos, F., Relva, A., Vasques, H., Gomes, A., et al. (2022) Benign Metastasizing Leiomyomatosis to the Skin and Lungs, Intravenous Leiomyomatosis, and Leiomyomatosis Peritonealis Disseminata: A Series of Five Cases. The Oncologist, 27, e89-e98. https://doi.org/10.1093/oncolo/oyab019 |
[7] | Baxter, B.L., Hur, H. and Guido, R.S. (2022) Emerging Treatment Options for Fibroids. Obstetrics and Gynecology Clinics of North America, 49, 299-314. https://doi.org/10.1016/j.ogc.2022.03.001 |
[8] | Sun, R., Guan, H., Li, H., Bai, Y., Wang, F. and Li, C. (2020) Computed Tomography Evaluation of Extensive Intravenous Angioleiomyoma: A Case Report. BMC Medical Imaging, 20, Article No. 13. https://doi.org/10.1186/s12880-020-0417-2 |
[9] | Mathey, M.P., Duc, C. and Huber, D. (2021) Intravenous Leiomyomatosis: Case Series and Review of the Literature. International Journal of Surgery Case Reports, 85, Article ID: 106257. https://doi.org/10.1016/j.ijscr.2021.106257 |
[10] | Schultz, K.L., Quinn, S.M., Miller, A.H., Fieman, R.E., Cipolle, M.D., Misselbeck, T.S., et al. (2021) Point of Care Ultrasound Facilitated Diagnosis of Right Ventricular Mass as the Etiology of Syncope; a Case Report of Intravenous Leiomyomatosis. Radiology Case Reports, 16, 1288-1293. https://doi.org/10.1016/j.radcr.2021.02.062 |
[11] | Marrone, G., Crinò, F., Morsolini, M., Caruso, S. and Miraglia, R. (2019) Multidisciplinary Approach in the Management of Uterine Intravenous Leiomyomatosis with Intracardiac Extension: Case Report and Review of Literature. Journal of Radiology Case Reports, 13, 1-13. https://doi.org/10.3941/jrcr.v13i7.3607 |
[12] | 范灵玲, 朱瑾, 陶祥, 徐丛剑. 子宫静脉内平滑肌瘤病64例临床病理分析[J]. 现代妇产科进展, 2015, 24(4): 262-265. |
[13] | 尹晶. 静脉内平滑肌瘤病超声误诊一例报告[J]. 社区医学杂志, 2021, 19(21): 1325-1328. |
[14] | 刘爽, 吴青青, 詹阳, 许阡, 陈照娟. 子宫静脉血管平滑肌瘤病的超声特征分析[J]. 中华医学超声杂志(电子版), 2017, 14(8): 630-635. |
[15] | 周清, 马凤华, 刘佳, 王雪珍, 田晓梅, 张国福. 子宫静脉内平滑肌瘤病的MRI表现[J]. 中国医学计算机成像杂志, 2016, 22(3): 243-248. |
[16] | 古聪敏, 余美融, 林汉良. 子宫静脉内平滑肌瘤病临床病理及免疫表型分析[J]. 诊断病理学杂志, 2009, 16(3): 198-200. |
[17] | 赵大春, 田庄, 梁智勇, 刘彤华. 静脉内平滑肌瘤病的临床病理[J]. 协和医学杂志, 2012, 3(1): 51-55. |
[18] | 王文泽, 马国涛, 肖雨, 梁智勇, 楼伟珍, 李霁, 赵大春, 吴焕文, 刘彤华. Bcl-2和血管内皮生长因子受体3在子宫静脉内平滑肌瘤病与普通型平滑肌瘤中的表达差异[J]. 协和医学杂志, 2014, 5(3): 297-301. |
[19] | 宋晓磊, 谢梅青. 子宫静脉内平滑肌瘤病的诊治进展[J]. 中国计划生育和妇产科, 2018, 10(10): 18-21+46. |
[20] | 马水清, 白春梅, 于晓红, 黄欧平, 郎景和, 李霁. 子宫静脉内平滑肌瘤临床病理分析[J]. 中华妇产科杂志, 2005(1): 37-40. |
[21] | 祝洪澜, 李佳, 李艺, 王悦, 鲍冬梅, 沈丹华, 崔恒. 18例静脉内平滑肌瘤病临床病理分析[J]. 中国妇产科临床杂志, 2017, 18(2): 137-140. |
[22] | 许阡, 金佟, 张佟, 臧春逸. 子宫静脉内平滑肌瘤病34例临床分析[J]. 中国医刊, 2022, 57(5): 549-554. |
[23] | 马国涛, 苗齐, 刘兴荣, 张超纪, 郑月宏, 邵江, 成宁海, 杜顺达, 刘剑州, 蒋超. 右侧心腔受累的静脉内平滑肌瘤病的外科治疗策略[J]. 中国医学科学院学报, 2016, 38(4): 438-443. |
[24] | 中国医师协会妇产科医师分会妇科肿瘤学组. 盆腔静脉内平滑肌瘤病临床诊治中国专家共识[J]. 中华妇产科杂志, 2023, 58(4): 252-258. |
[25] | Su, Q., Zhang, X., Zhang, H., Liu, Y., Dong, Z., Li, G., et al. (2020) Intravenous Leiomyomatosis of the Uterus: A Retrospective Single-Center Study in 14 Cases. BioMed Research International, 2020, Article ID: 9758302. https://doi.org/10.1155/2020/9758302 |
[26] | 吴琨, 魏丽惠. 子宫静脉内平滑肌瘤九例临床分析[J]. 中华肿瘤防治杂志, 2009, 16(9): 704-706. |
[27] | 张丽凤, 陈正云, 张信美. 子宫静脉内平滑肌瘤病9例临床分析[J]. 中国实用妇科与产科杂志, 2019, 35(12): 1360-1364. |
[28] | 弋文娟, 陈煜岊, 高彩云, 吴琨. 子宫静脉内平滑肌瘤病6例分析并文献复习[J]. 中国计划生育和妇产科, 2020, 12(11): 45-47+51. |
[29] | 王蛟, 张宁宁, 杨清. 子宫静脉内平滑肌瘤病48例临床分析[J]. 国际妇产科学杂志, 2020, 47(5): 554-557+601. |