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Stroke Secondary to an Intra-Carotid Thrombus in a Context of Antiphospholipid Syndrome and Thrombocytosis: Report of a Case

DOI: 10.4236/vp.2024.103022, PP. 268-277

Keywords: Thrombus, Anti-Phospholipids, Thrombocytosis

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Abstract:

Common carotid artery thrombosis (CCT) represents 7% of supraaortic artery thrombosis (TSA). CCT is responsible for neurological symptoms in 92% of cases. Antiphospholipe antibody syndrome (APS) is a rare cause, and its association with thrombocytosis is exceptional. We report a case of stenosing TBI secondary to APS associated with thrombocytosis discovered during a stroke. Ultrasound was the means of diagnosis and monitoring of CCT. The diagnosis of APS was biological. The cause of our patient’s thrombocytosis remains unknown. The treatment was only medical followed by a good clinical evolution. Anticoagulation has been used for treatment in the acute phase but also for the prevention of stroke recurrence.

References

[1]  Aibar, J., & Schulman, S. (2021). Erratum: Arterial Thrombosis in Patients with Antiphospholipid Syndrome: A Review and Meta-Analysis. Seminars in Thrombosis and Hemostasis, 47, e1-e2.
https://doi.org/10.1055/s-0042-1757330
[2]  Ambrosino, P., Lupoli, R., Di Minno, A., Iervolino, S., Peluso, R., & Di Minno, M. N. D. (2014). Markers of Cardiovascular Risk in Patients with Antiphospholipid Syndrome: A Meta-Analysis of Literature Studies. Annals of Medicine, 46, 693-702.
https://doi.org/10.3109/07853890.2014.959559
[3]  Ames, P. R. J., Antinolfi, I., Scenna, G., Gaeta, G., Margaglione, M., & Margarita, A. (2009). Atherosclerosis in Thrombotic Primary Antiphospholipid Syndrome. Journal of Thrombosis and Haemostasis, 7, 537-542.
https://doi.org/10.1111/j.1538-7836.2009.03308.x
[4]  Basili, S., & Violi, F. (2008). Aspirin in Asymptomatic Patients with a Confirmed Positivity of Antiphospholipid Antibodies. Internal and Emergency Medicine, 3, 373-374.
https://doi.org/10.1007/s11739-008-0193-4
[5]  Batista, T. F. P., Manuel, P. F., & Correia, A. C. (2019). Essential Thrombocythemia—A Predisponent Factor for Stroke. Revista da Associação Médica Brasileira, 65, 772-774.
https://doi.org/10.1590/1806-9282.65.6.772
[6]  Bertrand, A., Heissat, S., Caron, N., Viremouneix, L., Pracros, J., Javouhey, E. et al. (2014). Thrombose splanchnique révélatrice d’un syndrome myéloprolifératif chez deux adolescentes. Archives de Pédiatrie, 21, 497-500.
https://doi.org/10.1016/j.arcped.2014.02.019
[7]  Bhatti, A. F., Leon, L. R., Labropoulos, N., Rubinas, T. L., Rodriguez, H., Kalman, P. G. et al. (2007). Free-Floating Thrombus of the Carotid Artery: Literature Review and Case Reports. Journal of Vascular Surgery, 45, 199-205.
https://doi.org/10.1016/j.jvs.2006.09.057
[8]  Bots, M. L., & Grobbee, D. E. (2002). Intima Media Thickness as a Surrogate Marker for Generalised Atherosclerosis. Cardiovascular Drugs and Therapy, 16, 341-351.
https://doi.org/10.1023/a:1021738111273
[9]  Bouly, S., Le Bayon, A., Blard, J., Touzé, E., Leys, D., Mas, J. et al. (2005). Thrombus endoluminal de l’artère carotide sans lésion sous-jacente. Revue Neurologique, 161, 61-66.
https://doi.org/10.1016/s0035-3787(05)84974-4
[10]  Busch, M., Klingebiel, R., Bohner, G., & Masuhr, F. (2002). Intraluminal Carotid Thrombus. Neurology, 58, 986-986.
https://doi.org/10.1212/wnl.58.6.986
[11]  Cancer-Perez, S., Alfayate-García, J., Vicente-Jiménez, S., Ruiz-Muñoz, M., Dhimes-Tejada, F. P., Gutiérrez-Baz, M. et al. (2021). Symptomatic Common Carotid Free-Floating Thrombus in a COVID-19 Patient, Case Report and Literature Review. Annals of Vascular Surgery, 73, 122.E1-122.E7.
https://doi.org/10.1016/j.avsg.2021.02.008
[12]  Caplan, L. R. (2003). Resolved: Heparin May Be Useful in Selected Patients with Brain Ischemia. Stroke, 34, 230-231.
https://doi.org/10.1161/01.str.0000047036.77466.e8
[13]  Cervera, R., Piette, J., Font, J., Khamashta, M. A., Shoenfeld, Y., Camps, M. T. et al. (2002). Antiphospholipid Syndrome: Clinical and Immunologic Manifestations and Patterns of Disease Expression in a Cohort of 1,000 Patients. Arthritis & Rheumatism, 46, 1019-1027.
https://doi.org/10.1002/art.10187
[14]  Crassard, I., & Woimant, F. (2005). Affections hématologiques et accidents vasculaires cérébraux. EMC—Neurologie, 2, 339-348.
https://doi.org/10.1016/s0246-0378(05)27714-x
[15]  De Groot, P. G., & Derksen, R. H. W. M. (2005). Pathophysiology of the Antiphospholipid Syndrome. Journal of Thrombosis and Haemostasis, 3, 1854-1860.
https://doi.org/10.1111/j.1538-7836.2005.01359.x
[16]  de Laat, H. B., Derksen, R. H. W. M., Urbanus, R. T., Roest, M., & de Groot, P. G. (2004). Β2-glycoprotein I-Dependent Lupus Anticoagulant Highly Correlates with Thrombosis in the Antiphospholipid Syndrome. Blood, 104, 3598-3602.
https://doi.org/10.1182/blood-2004-03-1107
[17]  Dermitzakis, I., Minardos, I., Kampanarou, M., & Mitakou, D. (2002). Color Duplex Sonography of Occlusion of the Common Carotid Artery with Reversed Flow in the Extracranial Internal Carotid Artery. Journal of Clinical Ultrasound, 30, 388-391.
https://doi.org/10.1002/jcu.10075
[18]  Di Minno, M. N. D., Tufano, A., Ageno, W., Prandoni, P., & Di Minno, G. (2012). Identifying High-Risk Individuals for Cardiovascular Disease: Similarities between Venous and Arterial Thrombosis in Perspective. a 2011 Update. Internal and Emergency Medicine, 7, 9-13.
https://doi.org/10.1007/s11739-011-0582-y
[19]  Elijovich, L., Mainali, S., Doss, V., Arthur, A., & Watridge, C. (2013). Medical Management of Free-Floating Carotid Thrombus. Clinical Neurology and Neurosurgery, 115, 1532-1535.
https://doi.org/10.1016/j.clineuro.2012.12.017
[20]  Espinosa, G., & Cervera, R. (2010). Antiphospholipid Syndrome: Frequency, Main Causes and Risk Factors of Mortality. Nature Reviews Rheumatology, 6, 296-300.
https://doi.org/10.1038/nrrheum.2010.47
[21]  Eudo, M., & De Bray, J. (2000). Floating Thrombus in the Carotid. Radiology, 81, 1713-1714.
[22]  Ferrero, E., Ferri, M., Viazzo, A., Labate, C., Pecchio, A., Berardi, G. et al. (2011a). Thrombus libre flottant de l’artère carotide interne: Diagnostic et traitement de 16 cas dans un centre. Annales de Chirurgie Vasculaire, 25, 859-866.
https://doi.org/10.1016/j.acvfr.2012.09.019
[23]  Ferrero, E., Ferri, M., Viazzo, A., Labate, C., Pecchio, A., Berardi, G. et al. (2011b). Free-floating Thrombus in the Internal Carotid Artery: Diagnosis and Treatment of 16 Cases in a Single Center. Annals of Vascular Surgery, 25, 805-812.
https://doi.org/10.1016/j.avsg.2011.02.030
[24]  Fridman, S., Lownie, S. P., & Mandzia, J. (2019). Diagnosis and Management of Carotid Free-Floating Thrombus: A Systematic Literature Review. International Journal of Stroke, 14, 247-256.
https://doi.org/10.1177/1747493019828554
[25]  Furlan, J. C., Fang, J., & Silver, F. L. (2016). Outcomes after Acute Ischemic Stroke in Patients with Thrombocytopenia or Thrombocytosis. Journal of the Neurological Sciences, 362, 198-203.
https://doi.org/10.1016/j.jns.2016.01.044
[26]  Goyal, M., Menon, B. K., van Zwam, W. H., Dippel, D. W. J., Mitchell, P. J., Demchuk, A. M. et al. (2016). Endovascular Thrombectomy After Large-Vessel Ischaemic Stroke: A Meta-Analysis of Individual Patient Data from Five Randomised Trials. The Lancet, 387, 1723-1731.
https://doi.org/10.1016/s0140-6736(16)00163-x
[27]  Hagiwara, N., Nishimura, Y., Toyoda, K., Fujimoto, S., & Okada, Y. (2003). Embolic Stroke with Mobile Thrombus in Carotid Artery Induced by Antiphospholipid Antibody Syndrome. Rinsho Shinkeigaku, 43, 366-369.
[28]  Kazantsev, A. N., Karkayeva, M. R., Tritenko, A. P., Korotkikh, A. V., Zharova, A. S., Chernykh, K. P. et al. (2023). Carotid Enadrterectomy for Thrombosis of the Internal Carotid Artery in Patients with Covid-19. Current Problems in Cardiology, 48, Article ID: 101252.
https://doi.org/10.1016/j.cpcardiol.2022.101252
[29]  Khalfi, M., Khattab, H., Haddouali, K., Bellakhdar, S., El Otmani, H., El Moutawakil, B. et al. (2024). Le thrombus libre flottant de la carotide interne: Le challenge thérapeutique à travers une série de cas. Revue Neurologique, 180, S92.
https://doi.org/10.1016/j.neurol.2024.02.176
[30]  Kim, J., Jung, K., & Park, K. (2019). Radiological Features and Outcomes of Essential Thrombocythemia-Related Stroke. Journal of the Neurological Sciences, 398, 135-137.
https://doi.org/10.1016/j.jns.2019.01.035
[31]  Koge, J., Matsumoto, S., Nakahara, I., Ishii, A., Hatano, T., Tanaka, Y. et al. (2020). Impact of Thrombus Migration on Clinical Outcomes in Patients with Internal Carotid Artery Occlusions and Patent Middle Cerebral Artery. Journal of the Neurological Sciences, 412, Article ID: 116737.
https://doi.org/10.1016/j.jns.2020.116737
[32]  Lane, T. R. A., Shalhoub, J., Perera, R., Mehta, A., Ellis, M. R., Sandison, A. et al. (2010). Diagnosis and Surgical Management of Free-Floating Thrombus within the Carotid Artery. Vascular and Endovascular Surgery, 44, 586-593.
https://doi.org/10.1177/1538574410375312
[33]  Li, W., Yin, Q., Xu, G., & Liu, X. (2016). Treatment Strategies for Acute Ischemic Stroke Caused by Carotid Artery Occlusion. Interventional Neurology, 5, 148-156.
https://doi.org/10.1159/000445304
[34]  Martínez, R. C., Quaynor, S., Alkhalifah, M., & Goldenberg, F. D. (2018). Plateletpheresis: Nonoperative Management of Symptomatic Carotid Thrombosis in a Patient with Reactive Thrombocytosis. World Neurosurgery, 114, 126-129.
https://doi.org/10.1016/j.wneu.2018.03.075
[35]  Mittal, P., Quattrocchi, G., Tohidi-Esfahani, I., Sayar, Z., Chandratheva, A., & Cohen, H. (2023). Antiphospholipid Syndrome, Antiphospholipid Antibodies, and Stroke. International Journal of Stroke, 18, 383-391.
https://doi.org/10.1177/17474930221150349
[36]  Naylor, A. R., Schroeder, T. V., & Sillesen, H. (2014). Clinical and Imaging Features Associated with an Increased Risk of Late Stroke in Patients with Asymptomatic Carotid Disease. European Journal of Vascular and Endovascular Surgery, 48, 633-640.
https://doi.org/10.1016/j.ejvs.2014.08.017
[37]  Nelson, A., Nankee, C., & Banerjee, C. (2022). Iron Deficiency Anemia with Reactive Thrombocytosis Associated with Internal Carotid Artery Thrombus and Ischemic Infarction (p2-10.004). Neurology, 98, 3373.
https://doi.org/10.1212/wnl.98.18_supplement.3373
[38]  Pósfai, É., Marton, I., Szőke, A., Borbényi, Z., Vécsei, L., Csomor, A. et al. (2014). Stroke in Essential Thrombocythemia. Journal of the Neurological Sciences, 336, 260-262.
[39]  https://doi.org/10.1016/j.jns.2013.10.016
[40]  Richard, S., Perrin, J., Baillot, P. A, Lacour, J. C., & Ducrocq, X. (2011). Ischaemic Stroke and Essential Thrombocythemia: A Series of 14 Cases. European Journal of Neurology, 18, 995-998.
https://doi.org/10.1111/j.1468-1331.2010.03183.x
[41]  Rothwell, P. M. (2006). Medical and Surgical Management of Symptomatic Carotid Stenosis. International Journal of Stroke, 1, 140-149.
https://doi.org/10.1111/j.1747-4949.2006.00047.x
[42]  Rothwell, P. M. (2008). Endarterectomy for Symptomatic and Asymptomatic Carotid Stenosis. Neurologic Clinics, 26, 1079-1097.
https://doi.org/10.1016/j.ncl.2008.09.013
[43]  Rothwell, P., Eliasziw, M., Gutnikov, S., Fox, A., Taylor, D., Mayberg, M. et al. (2003). Analysis of Pooled Data from the Randomised Controlled Trials of Endarterectomy for Symptomatic Carotid Stenosis. The Lancet, 361, 107-116.
https://doi.org/10.1016/s0140-6736(03)12228-3
[44]  Sanna, G. (2003). Central Nervous System Involvement in the Antiphospholipid (Hughes) Syndrome. Rheumatology, 42, 200-213.
https://doi.org/10.1093/rheumatology/keg080
[45]  Silver, B., Gulka, I., Nicolle, M., Sahjpaul, R., & Hachinski, V. (2002). Idiopathic Free-Floating Thrombus of the Common Carotid Artery. Canadian Journal of Neurological Sciences/Journal Canadien des Sciences Neurologiques, 29, 97-99.
https://doi.org/10.1017/s0317167100001815
[46]  Suzuki, K., Sezai, A., & Tanaka, M. (2020). Unsuccessful Surgical Treatment of Thoracic Aortic Thrombosis in a Patient with Essential Thrombocythemia. Journal of Cardiac Surgery, 35, 236-238.
https://doi.org/10.1111/jocs.14286
[47]  Tefferi, A., Thiele, J., Orazi, A., Kvasnicka, H. M., Barbui, T., Hanson, C. A. et al. (2007). Proposals and Rationale for Revision of the World Health Organization Diagnostic Criteria for Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofibrosis: Recommendations from an Ad Hoc International Expert Panel. Blood, 110, 1092-1097.
https://doi.org/10.1182/blood-2007-04-083501
[48]  Tufano, A., Guida, A., Di Minno, M. N. D., De Gregorio, A. M., Cerbone, A. M., & Di Minno, G. (2010). Cardiovascular Events in Patients with Antiphospholipid Antibodies: Strategies of Prevention. Nutrition, Metabolism and Cardiovascular Diseases, 20, 217-223.
https://doi.org/10.1016/j.numecd.2009.10.016
[49]  Ukkola-Pons, E., Sadik, J. C., Champtiaux, N., Savatovsky, J., Heran, F., Gout, O. et al. (2012). Thrombus flottant sur un mégabulbe carotidien ou sur un bulbe suspendu, quel type de dysplasie? Revue Neurologique, 168, 53-56.
https://doi.org/10.1016/j.neurol.2011.03.009
[50]  Vannucchi, A. M., & Barbui, T. (2007). Thrombocytosis and Thrombosis. Hematology, 2007, 363-370.
https://doi.org/10.1182/asheducation-2007.1.363
[51]  Vardiman, J. W., Harris, N. L., & Brunning, R. D. (2002). The World Health Organization (WHO) Classification of the Myeloid Neoplasms. Blood, 100, 2292-2302.
https://doi.org/10.1182/blood-2002-04-1199
[52]  Vassileva, E., Daskalov, M., & Stamenova, P. (2015). Free-Floating Thrombus in Stroke Patients with Nonstenotic Internal Carotid Artery—An Ultrasonographic Study. Journal of Clinical Ultrasound, 43, 34-38.
https://doi.org/10.1002/jcu.22172
[53]  Vellimana, A. K., Kadkhodayan, Y., Rich, K. M., Cross, D. T., Moran, C. J., Zazulia, A. R. et al. (2013). Symptomatic Patients with Intraluminal Carotid Artery Thrombus: Outcome with a Strategy of Initial Anticoagulation. Journal of Neurosurgery, 118, 34-41.
https://doi.org/10.3171/2012.9.jns12406
[54]  Yonemura, K., Klmura, K., Yasaka, M., & Mlnematsu, K. (2003). Disappearance of an Oscillating Intraluminal Thrombus in the Carotid Artery Demonstrated by Ultrasonography. Internal Medicine, 42, 746-749.
https://doi.org/10.2169/internalmedicine.42.746

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