Context and Objectives: Stomach cancer ranks fifth in incidence and fourth in mortality worldwide. In Senegal, there were 597 new cases in 2020, with a mortality rate of almost 70%. The aim of this study was to develop a machine-learning model for the prognosis of death from stomach cancer 5 years after treatment. Methods: Our study sample consisted of 262 patients treated for gastric cancer at Aristide le Dantec Hospital and followed postoperatively between 2007 and 2020. We developed a multilayer perceptron with optimal hyperparameters and compared its performance with standard classification algorithms. We also augmented our data with a set of synthetic data generators to evaluate the behaviour of the model when faced with a larger amount of data. Results: Our model obtained an accuracy of 97.5%, outperforming the SVM (93%), RF (93.8%) and KNN (92.7%) models. An improvement of 1.5% in accuracy was achieved with synthetic data. Our study showed that the most pejorative factors in the evolution of the cancer were the appearance of hepatic metastases or adenopathy, smoking, and the infiltrative and stenosing aspects of the tumour on endoscopy. Conclusion: Our model predicted the occurrence of death from gastric cancer with very high accuracy, outperforming standard classification algorithms. The increase in training data produced an improvement in accuracy. Our study will help doctors to personalize the management of gastric cancer patients.
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