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炎性细胞与缺血性卒中的研究进展
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Abstract:
急性脑血管疾病包括急性出血性卒中和急性缺血性卒中。目前急性缺血性卒中是我国致死及致残的主要原因之一，亦是全球最常见的卒中类型。作为一种重要的病理机制，急性脑梗死发生后炎症免疫反应会被激活。最为常见的炎症指标是外周血中的白细胞、中性粒细胞、淋巴细胞、单核细胞。本文从神经炎症机制和中性粒细胞、单核细胞、淋巴细胞在发生缺血性卒中后的炎症反应以及炎症相关指标对脑梗死的预测作用进行综述。
Acute cerebrovascular diseases include acute hemorrhagic stroke and acute ischemic stroke. At present, acute ischemic stroke is one of the main causes of death and disability in China, and it is also the most common type of stroke worldwide. As an important pathological mechanism, the inflammatory immune response is activated after acute cerebral infarction occurs. The most common inflammatory markers are white blood cells, neutrophils, lymphocytes, and monocytes in peripheral blood. This article reviews the mechanisms of neuroinflammation and the inflammatory responses of neutrophils, monocytes, and lymphocytes after ischemic stroke, as well as the predictive role of inflammation related indicators for cerebral infarction.
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