The recent global spread of the pandemic underscores the necessity of seeking new materials effective against microorganisms. Nanotechnology offers avenues for developing multifunctional materials. In this study, alpha-titanium phosphate (α-TiP) nanoparticles were synthesized and treated with silver salt to enhance their antimicrobial properties. The physicochemical characteristics and antimicrobial activity were evaluated. It was revealed by X-ray diffraction analysis that the structural integrity of α-TiP was influenced by ethylenediamine and silver ions. Distinct degradation profiles for each chemical modification were shown by thermogravimetric analysis. Infrared spectroscopy detected shifts and new absorption peaks in the spectra depending on the type of modification. Energy dispersive spectroscopy confirmed the disaggregation of α-TiP galleries following the addition of silver salt, which increased their effectiveness against microorganisms. Notably, only the sample treated with silver ions exhibited antimicrobial action. Antimicrobial activity was tested against the bacteria of medical importance Escherichia coli, Salmonella Enteritidis, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus cereus, Listeria momocytogenes and the yeast Candida albicans. All microorganisms were inhibited by sample containing silver. Minor inhibition was observed against the Gram-positive bacteria L. monocytogenes and Bacillus cereus, while the greatest inhibition occurred against the fungus (yeast) C. albicans. The results revealed a potential application of the nanoparticles for control of microorganisms in public health.
References
[1]
Zhao, H. and Yuan, Z. (2020) Insights into Transition Metal Phosphate Materials for Efficient Electrocatalysis. ChemCatChem, 12, 3797-3810. https://doi.org/10.1002/cctc.202000360
[2]
Tan, S., Yue, J., Tian, Y., Ma, Q., Wan, J., Xiao, Y., et al. (2021) In-Situ Encapsulating Flame-Retardant Phosphate into Robust Polymer Matrix for Safe and Stable Quasi-Solid-State Lithium Metal Batteries. Energy Storage Materials, 39, 186-193. https://doi.org/10.1016/j.ensm.2021.04.020
[3]
Amghouz, Z., García, J.R. and Adawy, A. (2022) A Review on the Synthesis and Current and Prospective Applications of Zirconium and Titanium Phosphates. Eng, 3, 161-174. https://doi.org/10.3390/eng3010013
[4]
Bashir, A., Ahad, S., Malik, L.A., Qureashi, A., Manzoor, T., Dar, G.N., et al. (2020) Revisiting the Old and Golden Inorganic Material, Zirconium Phosphate: Synthesis, Intercalation, Surface Functionalization, and Metal Ion Uptake. Industrial & Engineering Chemistry Research, 59, 22353-22397. https://doi.org/10.1021/acs.iecr.0c04957
[5]
Wu, L., Wang, H., Kong, X., Wei, H., Chen, S. and Chi, L. (2023) High Strontium Adsorption Performance of Layered Zirconium Phosphate Intercalated with a Crown Ether. RSC Advances, 13, 6346-6355. https://doi.org/10.1039/d2ra07757d
[6]
Garcia, E.E., Albitres, G.A.V., Freitas, D.F.S., Mariano, D.M. and Mendes, L.C. (2022) Zinc and Silver Salts-Containing Lamellar Titanium Phosphate: A Multifunctional Filler. Materials Sciences and Applications, 13, 366-388. https://doi.org/10.4236/msa.2022.136021
[7]
García-Glez, J., Trobajo, C., Adawy, A. and Amghouz, Z. (2019) Exfoliation and Europium(iii)-Functionalization of Α-Titanium Phosphate via Propylamine Intercalation: From Multilayer Assemblies to Single Nanosheets. Adsorption, 26, 241-250. https://doi.org/10.1007/s10450-019-00133-2
[8]
Salam, M.A., Al-Amin, M.Y., Salam, M.T., Pawar, J.S., Akhter, N., Rabaan, A.A., et al. (2023) Antimicrobial Resistance: A Growing Serious Threat for Global Public Health. Healthcare, 11, Article 1946. https://doi.org/10.3390/healthcare11131946
[9]
Maillard, J.-Y. (2007) Bacterial Resistance to Biocides in the Healthcare Environment: Should It Be of Genuine Concern? Journal of Hospital Infection, 65, 60-72. https://doi.org/10.1016/s0195-6701(07)60018-8
[10]
Alonso, V.P.P., Furtado, M.M., Iwase, C.H.T., Brondi-Mendes, J.Z. and Nascimento, M.d.S. (2022) Microbial Resistance to Sanitizers in the Food Industry: Review. Critical Reviews in Food Science and Nutrition, 64, 654-669. https://doi.org/10.1080/10408398.2022.2107996
[11]
Ahamed, M.S., Ali, M.S., Ahmed, S., Sadia, S.I., Islam, M.R., Rahaman, M.A., et al. (2024) Synthesis of Silver Nanomaterials Capping by Fruit-Mediated Extracts and Antimicrobial Activity: A Critical Review. International Research Journal of Pure and Applied Chemistry, 25, 45-60. https://doi.org/10.9734/irjpac/2024/v25i1844
[12]
Nekooei-Fard, M., Jahanmardi, R., Fazaeli, R. and Sohrabi-Haghdoost, N. (2023) Effects of Zeolite Loaded with Silver, Copper, or Zinc Ions on Antimicrobial Properties of the Ethylene-Vinyl Acetate Copolymer. Polymers for Advanced Technologies, 35, e6237. https://doi.org/10.1002/pat.6237
[13]
Nasiri, S. and Jafarizadeh-Malmiri, H. (2024) Microwave Irradiation in Green Antimicrobial Silver Nanoparticles Synthesis Using Arabic Gum: Preparation, Optimization and Characterization. Journal of Chemical and Petroleum Engineering, 58, 149-163.
[14]
Karci, H., Dündar, M., Nawaz, Z., Özdemir, İ., Gürbüz, N., Koç, A., et al. (2024) Sythesis, Characterisation, Anticancer and Antimicrobial Activity of Ag-N-Heterocyclic Carbene Complexes Containing Benzimidazole Derivatives. InorganicaChimica Acta, 565, Article 121992. https://doi.org/10.1016/j.ica.2024.121992
[15]
Albitres, G.A.V., Cestari, S.P., Freitas, D.F.S., Rodrigues, D.C., Mendes, L.C. and Neumann, R. (2019) Intercalation of Α-Titanium Phosphate with Long-Chain Amine Aided by Short-Chain Amine. Applied Nanoscience, 10, 907-916. https://doi.org/10.1007/s13204-019-01176-1
[16]
Hou, Y., Pan, Y., Dong, C. and Nie, B. (2020) Direct Transformation of Agno3 Complex Encapsulated Fullerene (c60) Microcrystal on Solid Silver Nitrate Crystal without Organic Ligands. Applied Organometallic Chemistry, 34, e5978. https://doi.org/10.1002/aoc.5978
[17]
Aziz, S., Abdulwahid, R., Rasheed, M., Abdullah, O. and Ahmed, H. (2017) Polymer Blending as a Novel Approach for Tuning the SPR Peaks of Silver Nanoparticles. Polymers, 9, Article 486. https://doi.org/10.3390/polym9100486
[18]
Amghouz, Z., Mendoza-Meroño, R. and Adawy, A. (2023) Nucleation & Growth of Α-Ti(HPO4)2·H2O Single-Crystal and Its Structure Determination from X-Ray Single-Crystal Data. Journal of Solid State Chemistry, 327, Article 124251. https://doi.org/10.1016/j.jssc.2023.124251
[19]
Wang, C., Cheng, Q. and Wang, Y. (2018) Anion-Controlled Cation-Exchange Process: Intercalating Α-Titanium Phosphate through Direct Ion Exchange with Alkylammonium Salts. Inorganic Chemistry, 57, 3753-3760. https://doi.org/10.1021/acs.inorgchem.7b03030
[20]
Ortíz-Oliveros, H.B., Flores-Espinosa, R.M., Ordoñez-Regil, E. and Fernández-Valverde, S.M. (2014) Synthesis of Α-Ti(HPO4)2·H2O and Sorption of Eu (iii). Chemical Engineering Journal, 236, 398-405. https://doi.org/10.1016/j.cej.2013.09.103
[21]
Peng, W., Wang, X., Wang, M., Wang, Y. and Cheng, Q. (2020) Embedding Alkyldiamine into Layered Α‐Titanium Phosphate via Direction Exchange and Its Application in Euiii Removal from Water. Zeitschrift für anorganische und allgemeineChemie, 646, 399-406. https://doi.org/10.1002/zaac.201900349
[22]
Narayanan, A. and Dhamodharan, R. (2015) Super Water-Absorbing New Material from Chitosan, EDTA and Urea. Carbohydrate Polymers, 134, 337-343. https://doi.org/10.1016/j.carbpol.2015.08.010
[23]
Janković, B., Stopić, S., Bogović, J. and Friedrich, B. (2014) Kinetic and Thermodynamic Investigations of Non-Isothermal Decomposition Process of a Commercial Silver Nitrate in an Argon Atmosphere Used as the Precursors for Ultrasonic Spray Pyrolysis (USP): The Mechanistic Approach. Chemical Engineering and Processing: Process Intensification, 82, 71-87. https://doi.org/10.1016/j.cep.2014.06.002
[24]
Magdalena, A.G., Silva, I.M.B., Marques, R.F.C., Pipi, A.R.F., Lisboa-Filho, P.N. and Jafelicci, M. (2018) Edta-Functionalized Fe3O4 Nanoparticles. Journal of Physics and Chemistry of Solids, 113, 5-10. https://doi.org/10.1016/j.jpcs.2017.10.002
[25]
Augustine, R., Kalarikkal, N. and Thomas, S. (2013) A Facile and Rapid Method for the Black Pepper Leaf Mediated Green Synthesis of Silver Nanoparticles and the Antimicrobial Study. Applied Nanoscience, 4, 809-818. https://doi.org/10.1007/s13204-013-0260-7
[26]
Garcia, E.E., Albitres, G.A.V., Freitas, D.F.S., Mariano, D.M. and Mendes, L.C. (2023) Dyeability of Composite Based on Recycled Poly(ethylene Terephthalate) Filled with Pristine and Zinc/Silver-Modifying Titanium Phosphate. Fibers and Polymers, 25, 577-586. https://doi.org/10.1007/s12221-023-00437-9
[27]
Prestch, E., Buhlmann, P. and Affolter, C. (2000) Structure Determination of Organic Compounds. Springer.
[28]
Estevez, M.B., Raffaelli, S., Mitchell, S.G., Faccio, R. and Alborés, S. (2020) Biofilm Eradication Using Biogenic Silver Nanoparticles. Molecules, 25, Article 2023. https://doi.org/10.3390/molecules25092023
[29]
Saravanan, M., Arokiyaraj, S., Lakshmi, T. and Pugazhendhi, A. (2018) Synthesis of Silver Nanoparticles from Phenerochaete Chrysosporium (MTCC-787) and Their Antibacterial Activity against Human Pathogenic Bacteria. Microbial Pathogenesis, 117, 68-72. https://doi.org/10.1016/j.micpath.2018.02.008
[30]
Kim, J.S., Kuk, E., Yu, K.N., Kim, J., Park, S.J., Lee, H.J., et al. (2007) Antimicrobial Effects of Silver Nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine, 3, 95-101. https://doi.org/10.1016/j.nano.2006.12.001
[31]
Rahisuddin, AL-Thabaiti, S.A., Khan, Z. and Manzoor, N. (2015) Biosynthesis of Silver Nanoparticles and Its Antibacterial and Antifungal Activities towards Gram-Positive, Gram-Negative Bacterial Strains and Different Species of Candida Fungus. Bioprocess and Biosystems Engineering, 38, 1773-1781. https://doi.org/10.1007/s00449-015-1418-3
[32]
Manimaran, K., Yanto, D.H.Y., Anita, S.H., Nurhayat, O.D., Selvaraj, K., Basavarajappa, S., et al. (2023) Synthesis and Characterization of Hypsizygus Ulmarius Extract Mediated Silver Nanoparticles (AgNPs) and Test Their Potentiality on Antimicrobial and Anticancer Effects. Environmental Research, 235, Article 116671. https://doi.org/10.1016/j.envres.2023.116671
[33]
Gandhi, M. and Chikindas, M.L. (2007) Listeria: A Foodborne Pathogen That Knows How to Survive. International Journal of Food Microbiology, 113, 1-15. https://doi.org/10.1016/j.ijfoodmicro.2006.07.008
[34]
Belluco, S., Losasso, C., Patuzzi, I., Rigo, L., Conficoni, D., Gallocchio, F., et al. (2016) Silver as Antibacterial toward Listeria Monocytogenes. Frontiers in Microbiology, 7, Article 307. https://doi.org/10.3389/fmicb.2016.00307
[35]
Mohammed, A.N. and Abdel Aziz, S.A.A. (2018) Novel Approach for Controlling Resistant Listeria Monocytogenes to Antimicrobials Using Different Disinfectants Types Loaded on Silver Nanoparticles (AgNPs). Environmental Science and Pollution Research, 26, 1954-1961. https://doi.org/10.1007/s11356-018-3773-5
