Objective: To evaluate the treatment outcomes of micropulse cyclophotocoagulation in Cambodian glaucoma patients. Materials and Methods: 14 patients were enrolled in this retrospective study that was conducted with the consent over a 14-month period. The medical records were analyzed for variables such as intra-ocular pressure, the number of anti-glaucoma drugs used, visual acuity, pain level, and complications during and after treatment. The main outcome was whether or not there was success or failure, with success being defined as a pressure level between 6 and 21 mmHg and a 30% decrease in IOP by week 24 (with/without drugs). Results: In our study, the mean age of patients was 52.36 ± 9.98 years old (42 to 75 years old). The mean intra-ocular pressure before treatment was 41.00 ± 12.26 mmHg, which decreased to 21.60 ± 8.11 mmHg (41.56% reduction) and 16.94 ± 5.46 mmHg (56.04% reduction) in the 12th and 24th weeks (p < 0.001), respectively, with a success rate of 86%. Anti-glaucoma medications in average pre-treatment were 3.45 ± 0.89 (2 to 5 drugs), dropped to 1.85 ± 1.19 (1 to 3 drugs), and 1.46 ± 1.15 (none to 3 drugs) in weeks 12 and 24, with a mean reduction of 2, p < 0.001. The number of eyes with complications is limited to 3 (22.43%), but there has been no significant change in visual acuity. Conclusion: Micro-pulse trans-scleral cyclophotocoagulation is a safe and effective method for lowering pressure in any stage of disease without the use of invasive surgeries.
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