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炎症性肠病高凝状态机制的相关研究
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Abstract:
炎症性肠病(IBD)是一种累及回肠、结肠、直肠，病因尚未明确的肠道慢性疾病，其总发病率在各国均有所增加。研究证实炎症性肠病(IBD)患者循环系统处于高凝状态，这种高凝状态使得肠道微循环功能障碍，进一步加重炎症性肠病的疾病严重程度，甚至导致静脉血栓的发生。多项研究表明，IBD患者相较健康人群，其静脉血栓的发生风险增加。因此，对于炎症性肠病的患者来说，预防和治疗高凝状态具有重要意义。
Inflammatory bowel disease (IBD) is a chronic intestinal disease affecting the ileum, colon, and rectum of unknown etiology, and its overall incidence has increased in all countries. Studies have confirmed that the circulatory system of patients with inflammatory bowel disease (IBD) is in a hypercoagulable state, which makes the intestinal microcirculation dysfunction, further aggravates the severity of inflammatory bowel disease, and even leads to the occurrence of venous thrombosis. Several studies have shown that patients with IBD are at increased risk of venous thrombosis compared with healthy people. Therefore, it is important for patients with inflammatory bowel disease to prevent and treat hypercoagulability.
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