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新型冠状病毒感染大流行期间慢性阻塞性肺疾病患者使用皮质类固醇进展
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Abstract:
世卫组织最近关于在新型冠状病毒感染大流行期间使用全身性皮质类固醇的警告引起了公众对皮质类固醇的安全性及有效性的质疑。长期使用皮质类固醇的慢性阻塞性肺疾病患者则担心皮质类固醇是否对免疫系统对抗病毒感染具有潜在的有害影响。本综述详细总结了新型冠状病毒感染大流行期间慢性阻塞性肺疾病患者使用皮质类固醇最新进展，包括安全性、有效性、急性加重期的应用。
WHO’s recent warning on the use of systemic corticosteroids during the COVID-19 pandemic has raised public questions about the safety and efficacy of corticosteroids. Chronic obstructive pulmonary disease patients who use corticosteroids for a long time are concerned about whether corticosteroids have a potentially harmful effect on the immune system’s fight against viral infections. This review provides a detailed review of recent advances in the use of corticosteroids in patients with chronic obstructive pulmonary disease during the COVID-19 pandemic, including safety, efficacy, and use during acute exacerbations.
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