中西医结合治疗气虚血瘀型不稳定型心绞痛的研究进展
Research Progress on the Combination of Traditional Chinese and Western Medicine in the Treatment of Unstable Angina Pectoris of Qi Deficiency and Blood Stasis Type

不稳定型心绞痛(unstable angina, UA)是由于不稳定粥样硬化斑块糜烂或破裂，引起冠状动脉血流急剧减少，导致冠状动脉内血栓形成所致，胸痛为其最主要的临床表现。其发病机制有二种理论：一：是冠状动脉管腔因粥样硬化斑块导致的进行性狭窄；二：是不稳定的粥样斑块突然破裂。不稳定型心绞痛作为冠心病(coronary heart disease, CHD)的常见类型，西医治疗主要是手术治疗和药物治疗，其最终目的都是改善心肌血流供血，以缓解心绞痛等症状，药物治疗主要是以控制和防止血小板聚集、降低血脂和稳定住已形成的斑块，让其不再快速进展，但长期服用西药治疗，易导致肝肾功能受损、产生耐药等不良反应，且单纯使用西药治疗在改善患者长期预后等方面临床疗效欠佳。中医药治疗原则是整体观念，辨证论治，若与西医联合疗法，不仅临床效果能进一步的提高，在改善病人生存质量、延长患者寿命、减少长期服用西药带来的不良反应方面有大大的优势，因此，本文对中西医结合治疗不稳定型心绞痛的综述如下。
Unstable angina (UA) is caused by erosion or rupture of unstable atherosclerotic plaques, which causes a sharp decrease in coronary blood flow, resulting in intra-coronary thrombosis, and chest pain is the main clinical manifestation. There are two theories of its pathogenesis: one is the progressive narrowing of coronary lumen caused by atherosclerotic plaque; the other is the sudden rupture of unstable atherosclerotic plaques. Unstable angina pectoris, as a common type of coronary heart disease (CHD), is mainly treated by Western medicine through surgery and medication, with the ultimate goal of improving myocardial blood flow and supply to alleviate symptoms such as angina pectoris. The main purpose of drug treatment is to control and prevent platelet aggregation, reduce blood lipids and stabilize the plaque that has been formed, so that it will not progress rapidly. However, long-term use of western medicine is easy to lead to liver and kidney function impairment, drug resistance and other adverse reactions, and the use of Western medicine alone has poor clinical efficacy in improving the long-term prognosis of patients. The principle of TCM treatment is a holistic concept and treatment based on syndrome differentiation. If it is combined with Western medicine, not only can the clinical effect be further improved, but also has great advantages in improving the quality of life of patients, extending the life span of patients and reducing the adverse reactions caused by long-term use of Western medicine. Therefore, this paper summarizes the treatment of unstable angina pectoris by combining Chinese and Western medicine as follows.