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甘油三酯/高密度脂蛋白胆固醇比值与2型糖尿病及其并发症的关系研究进展
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Abstract:
2型糖尿病(T2DM)是危害人类健康的最常见慢性疾病之一，其危害主要在于慢性并发症。胰岛素抵抗(IR)是T2DM的主要发病机制，也参与其慢性并发症的发生发展，早期识别IR对于预测及预防T2DM的发病、延缓疾病进展、改善患者生存质量都具有重要意义。甘油三酯/高密度脂蛋白胆固醇比值(TG/HDL-C)可作为IR的一项简单替代指标，且与T2DM及其慢性并发症存在着不同程度的相关性。
Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases jeopardizing human health, and its harm lies mainly in chronic complications. Insulin resistance (IR) is the main pathogenesis of T2DM and is also involved in the development of its chronic complications. Early identification of IR is important for predicting and preventing the onset of T2DM, delaying disease progression, and improving the quality of life of patients. Triglyceride/high-density lipoprotein cholesterol ratio (TG/HDL-C) can be used as a simple surrogate for IR and has been correlated with T2DM and its chronic complications to varying degrees.
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