|
|
GnRH-a治疗乙状结肠子宫内膜异位症1例
|
Abstract:
子宫内膜异位症(Endometriosis, EMT)指子宫内膜组织种植于子宫之外形成病灶，表现为痛经、不孕、慢性盆腔疼痛等多种症状。肠道子宫内膜异位症是深部浸润型子宫内膜异位症最严重的形式之一，临床少见，症状不典型，诊断困难。现将1例长效促性腺激素释放激素激动剂(GnRH-a)治疗乙状结肠子宫内膜异位症病例报告如下，通过对该病例的分析增加对于肠道子宫内膜异位症的认识，指导临床治疗。
Endometriosis (EMT) is a condition in which endometrial tissue implants outside the uterus, forming lesions that can cause symptoms such as painful periods, infertility, and chronic pelvic pain. Intestinal endometriosis is one of the most severe forms of deep infiltrating endometriosis and is a rare clinical condition with non-specific symptoms and difficulty in diagnosis. Here, we report a case of treatment with long-acting gonadotropin-releasing hormone agonist (GnRH-a) for sigmoid colon endometriosis. Through this analysis, our aim is to enhance understanding of intestinal endometriosis and provide guidance for clinical management.
| [1] | 中华预防医学会生殖健康分会, 中国医师协会妇产科医师分会子宫内膜异位症学组. 子宫内膜异位症疼痛管理指南(2024年实践版) [J]. 中国实用妇科与产科杂志, 2024, 40(1): 50-61. |
| [2] | Qiu, M., Wang, Y., Ren, R., Sun, Y., Xiao, S. and Han, L. (2023) Clinicopathological Correlations of Peritoneal Endometriosis and Deep Infiltrating Endometriosis. Annals of Medicine, 55, Article ID: 2244877. https://doi.org/10.1080/07853890.2023.2244877 |
| [3] | 王笑楠, 汪旭, 孙明军, 等. 超声内镜诊断肠道子宫内膜异位症的临床价值[J]. 中国医科大学学报, 2018, 47(11): 1036-1038. |
| [4] | Abrao, M.S., Petraglia, F., Falcone, T., Keckstein, J., Osuga, Y. and Chapron, C. (2015) Deep Endometriosis Infiltrating the Recto-Sigmoid: Critical Factors to Consider before Management. Human Reproduction Update, 21, 329-339. https://doi.org/10.1093/humupd/dmv003 |
| [5] | Jiang, W., Roma, A.A., Lai, K., Carver, P., Xiao, S. and Liu, X. (2013) Endometriosis Involving the Mucosa of the Intestinal Tract: A Clinicopathologic Study of 15 Cases. Modern Pathology, 26, 1270-1278. https://doi.org/10.1038/modpathol.2013.51 |
| [6] | Tosti, C., Pinzauti, S., Santulli, P., Chapron, C. and Petraglia, F. (2015) Pathogenetic Mechanisms of Deep Infiltrating Endometriosis. Reproductive Sciences, 22, 1053-1059. https://doi.org/10.1177/1933719115592713 |
| [7] | Yin, W., Li, X., Liu, P., Li, Y., Liu, J., Yu, S., et al. (2023) Digestive System Deep Infiltrating Endometriosis: What Do We Know. Journal of Cellular and Molecular Medicine, 27, 3649-3661. https://doi.org/10.1111/jcmm.17921 |
| [8] | Vercellini, P., Sergenti, G., Buggio, L., Frattaruolo, M.P., Dridi, D. and Berlanda, N. (2021) Advances in the Medical Management of Bowel Endometriosis. Best Practice & Research Clinical Obstetrics & Gynaecology, 71, 78-99. https://doi.org/10.1016/j.bpobgyn.2020.06.004 |
| [9] | 董燕, 孙琳. 肠道子宫内膜异位症诊治进展[J]. 中华实用诊断与治疗杂志, 2023, 37(2): 214-216. |
| [10] | Ferrero, S., Barra, F., Scala, C. and Condous, G. (2021) Ultrasonography for Bowel Endometriosis. Best Practice & Research Clinical Obstetrics & Gynaecology, 71, 38-50. https://doi.org/10.1016/j.bpobgyn.2020.05.010 |
| [11] | Koninckx, P.R., Ussia, A., Adamyan, L., Wattiez, A. and Donnez, J. (2012) Deep Endometriosis: Definition, Diagnosis, and Treatment. Fertility and Sterility, 98, 564-571. https://doi.org/10.1016/j.fertnstert.2012.07.1061 |
| [12] | Taylor, H.S., Kotlyar, A.M. and Flores, V.A. (2021) Endometriosis Is a Chronic Systemic Disease: Clinical Challenges and Novel Innovations. The Lancet, 397, 839-852. https://doi.org/10.1016/s0140-6736(21)00389-5 |
| [13] | Szubert, M., Zi？tara, M. and Suzin, J. (2017) Conservative Treatment of Deep Infiltrating Endometriosis: Review of Existing Options. Gynecological Endocrinology, 34, 10-14. https://doi.org/10.1080/09513590.2017.1381837 |
| [14] | Vannuccini, S., Clemenza, S., Rossi, M. and Petraglia, F. (2021) Hormonal Treatments for Endometriosis: The Endocrine Background. Reviews in Endocrine and Metabolic Disorders, 23, 333-355. https://doi.org/10.1007/s11154-021-09666-w |
