|
|
基于CiteSpace从脾论治2型糖尿病的可视化分析
|
Abstract:
目的：基于CiteSpace软件对从脾论治2型糖尿病(T2DM)的相关文献进行知识图谱可视化分析，探索从脾论治T2DM的研究热点和发展趋势。方法：以中国知网(CNKI)作为文献来源，检索2001~2021年近20年从脾论治T2DM的相关文献，应用CiteSpace6.1.R3软件对发文量、作者、机构、关键词进行分析并绘制相关知识图谱。结果：关键词共现网络由432个节点，774条线组成，共分成16个聚类。研究热点是从脾虚论治2型糖尿病的临床研究和经验、二甲双胍。潜在的研究方向是脂联素和代谢记忆。结论：通过可视化分析可以直观形象地了解该领域发展脉络、研究热点及潜在的研究趋势，为科研人员今后的研究提供研究依据和方向。
Objective: Based on CiteSpace software, the knowledge map visualization analysis of related literatures on treating type 2 diabetes from spleen was carried out to explore the research hotspots and development trends of treating type 2 diabetes from spleen. Methods: Taking China National Knowledge Infrastructure (CNKI) as the literature source, the relevant literatures on the treatment of T2 DM from spleen in the past 20 years from 2001 to 2021 were retrieved, and CiteSpace6.1.R3 software was used to analyze the number of articles, authors, institutions and keywords, and draw relevant knowledge maps. Results: The keyword co-occurrence network consisted of 432 nodes and 774 lines, which were divided into 16 clusters. The research hotspot is the clinical research and experience of treating type 2 diabetes from spleen deficiency and metformin. Potential research directions are adiponectin and metabolic memory. Conclusion: Through visual analysis, we can intuitively and vividly understand the development context, research hotspots and potential research trends in this field, and provide research basis and direction for researchers’ future research.
| [1] | Chatterjee, S., Khunti, K. and Davies, M.J. (2017) Type 2 Diabetes. The Lancet, 389, 2239-2251. https://doi.org/10.1016/S0140-6736(17)30058-2 |
| [2] | Sun, H., Saeedi, P., Karuranga, S., et al. (2022) IDF Diabetes Atlas: Global, Regional and Country-Level Diabetes Prevalence Estimates for 2021 and Projections for 2045. Diabetes Research and Clinical Practice, 183, Article ID: 109119. https://doi.org/10.1016/j.diabres.2021.109119 |
| [3] | Yan, Y.Q., Wu, T.T., Zhang, M., Li, C.F., Liu, Q. and Li, F. (2022) Prevalence, Awareness and Control of Type 2 Diabetes Mellitus and Risk Factors in Chinese Elderly Population. BMC Public Health, 22, Article No. 1382. https://doi.org/10.1186/s12889-022-13759-9 |
| [4] | 董昱, 王桦, 檀春玲, 等. 我国老年人四大慢性病流行现状及对伤残调整生命年的影响[J]. 医学与社会, 2019, 32(10): 59-61+65. |
| [5] | Polji？anin, T., Ajdukovi？, D., ？ekerija, M., et al. (2010) Diabetes Mellitus and Hypertension Have Comparable Adverse Effects on Health-Related Quality of Life. BMC Public Health, 10, Article No. 12. https://doi.org/10.1186/1471-2458-10-12 |
| [6] | Bonora, E., Trombetta, M., Dauriz, M., et al. (2020) Chronic Complications in Patients with Newly Diagnosed Type 2 Diabetes: Prevalence and Related Metabolic and Clinical Features: The Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 9. BMJ Open Diabetes Research & Care, 8, e001549. https://doi.org/10.1136/bmjdrc-2020-001549 |
| [7] | Kolari？, V. (2022) Chronic Complications of Diabetes and Quality of Life. Acta Clinica Croatica, 61, 520-527. https://doi.org/10.20471/acc.2022.61.03.18 |
| [8] | Baderca, F., Timar, B., Popescu, S., et al. (2016) Age as an Independent Factor for the Development of Neuropathy in Diabetic Patients. Clinical Interventions in Aging, 11, 313-318. https://doi.org/10.2147/CIA.S97295 |
| [9] | 刘承琴, 戚宏, 王荣欣. 2型糖尿病胰岛素抵抗当重视从脾论治[C]//第三届糖尿病(消渴病)国际学术会议论文集. 北京: 国际文化出版公司, 2002: 413-416. |
| [10] | 陈英群, 董福轮, 王宇锋, 等. 从脾论治胰岛素抵抗糖脂代谢紊乱的思路[J]. 中医杂志, 2008(3): 273-275. |
| [11] | 师林, 柯斌, 罗晓莉. 从脾虚痰湿角度探讨2型糖尿病胰岛素抵抗的中医研究思路[J]. 广州中医药大学学报, 2015, 32(2): 336-338. |
| [12] | 师林, 杨玉彬, 黄颖娟, 等. 健脾化湿方对脾虚痰湿型肥胖2型糖尿病胰岛素抵抗大鼠骨骼肌PI3K/Akt通路的影响[J]. 中华中医药杂志, 2018, 33(2): 530-534. |
| [13] | 叶英法, 刘怀珍. 从脾论治2型糖尿病合并脂质代谢紊乱的研究进展[J]. 四川中医, 2014, 32(4): 179-181. |
| [14] | 邹慧, 刘怀珍, 胡晓妍, 等. 复方葛根芩连汤治疗脾虚肝郁、痰瘀内阻型糖尿病合并非酒精性脂肪肝临床观察[J]. 安徽中医药大学学报, 2019, 38(1): 18-22. |
| [15] | 逄冰, 王佳笑, 史丽伟, 等. 倪青教授运用藿朴夏苓汤治疗2型糖尿病的经验[J]. 世界中西医结合杂志, 2022, 17(10): 1962-1964+1984. |
| [16] | 富晓旭, 刘桠, 高泓, 等. “脾气散精”环节在机体糖调节中发挥核心作用的理论探讨[J]. 中国中医基础医学杂志, 2021, 27(3): 398-399+426. |
| [17] | 晁俊, 张翕宇, 刘桠, 等. 参芪复方调控GK大鼠生物钟相关基因Id2、Usp2的实验研究[J]. 中国中西医结合杂志, 2021, 41(11): 1347-1352. |
| [18] | 田禄宇, 杨宇峰, 石岩. 基于“从脾论治”探讨中药复方益糖康调节肠道菌群防治2型糖尿病研究思路[J]. 辽宁中医药大学学报, 2023, 25(3): 183-187. |
| [19] | 王东, 李敬林, 姜良铎. 从“脾虚致消”建立2型糖尿病胰岛素抵抗大鼠模型[J]. 中华中医药学刊, 2007(12): 2538-2540. |
| [20] | 张愿, 谢红艳, 周琳悦, 等. 加味参芪复方治疗初诊脾虚型2型糖尿病临床观察[J]. 中华中医药学刊, 2019, 37(12): 2967-2970. |
| [21] | 陈悦, 陈超美, 刘则渊, 等. CiteSpace知识图谱的方法论功能[J]. 科学学研究, 2015, 33(2): 242-253. |
| [22] | 陈瑜凡, 王燕平, 荣培晶, 等. 糖尿病前期中医证型及证素特点分析[J]. 世界科学技术-中医药现代化, 2022, 24(2): 563-568. |
| [23] | 张伟. 健脾益气法治疗糖尿病探析[J]. 吉林中医药, 2009, 29(5): 369-370. |
| [24] | 杜积慧, 于文娟, 邴蕾蕾. 益气健脾方治疗2型糖尿病合并肥胖临床观察[J]. 山东中医杂志, 2022, 41(4): 396-400. |
| [25] | 李芳芳, 康学东. 加味逍遥散治疗肝郁脾虚型2型糖尿病伴情绪障碍患者的临床观察[J]. 中国实验方剂学杂志, 2019, 25(2): 134-138. |
| [26] | 田源, 运锋, 陈依键. 益气健脾汤治疗2型糖尿病(脾气亏虚型)的临床疗效观察[J]. 中医药学报, 2017, 45(4): 129-131. |
| [27] | 张琪, 杜顺棠, 季兵, 刘峰. 四逆散合甘麦大枣汤治疗2型糖尿病合并抑郁焦虑状态临床观察[J]. 广州中医药大学学报, 2022, 39(4): 763-769. |
| [28] | 杜立娟, 逄冰, 吴倩, 张一, 周雨桐, 索文栋, 倪青. 半夏泻心汤从脾论治糖尿病的理论基础及临床应用特点[J]. 辽宁中医杂志, 2021, 48(8): 58-61. |
| [29] | 史丽伟, 杜立娟, 倪青. 半夏泻心汤治疗糖尿病的理论探讨与临床应用[J]. 中医杂志, 2018, 59(3): 246-250. |
| [30] | 沈玉国, 冯程程, 叶婷, 李凯利. 消渴益气汤治疗2型糖尿病脾虚痰浊气阴两虚证临床疗效观察[J]. 四川中医, 2017, 35(6): 98-100. |
| [31] | 中国老年2型糖尿病防治临床指南(2022年版) [J]. 中国糖尿病杂志, 2022, 30(1): 2-51. |
| [32] | 朱岚, 魏燕, 金剑虹, 等. 芪山无糖颗粒治疗湿热困脾证初发2型糖尿病随机对照研究[J]. 中国中西医结合杂志, 2020, 40(2): 154-157. |
| [33] | 王漫, 薛莉, 张智龙, 等. 调中降糖颗粒对脾虚湿盛型2型糖尿病患者血糖及FFA、MDA水平的影响[J]. 山西中医, 2020, 36(11): 11-13+16. |
| [34] | Ono, S., Mizushiri, S., Nishiya, Y., et al. (2022) The Relationship between Serum Adiponectin, Urinary Albumin/Creatinine Ratio and Type 2 Diabetes: A Population-Based Cross-Sectional Study. Journal of Clinical Medicine, 11, 7232. https://doi.org/10.3390/jcm11237232 |
| [35] | 张越, 叶仁群, 梁奇, 等. 芪丹颗粒治疗脾虚痰瘀型2型糖尿病患者的临床疗效观察[J]. 世界中西医结合杂志, 2019, 14(11): 1600-1604. |
| [36] | 高平, 涂杰辉. 参苓白术散加减治疗肥胖型2型糖尿病脾虚湿困证的效果及对患者脂肪激素与胃肠激素的调节效果观察[J]. 实用妇科内分泌电子杂志, 2020, 7(23): 164-165. |
| [37] | 周环宇, 贾中芝, 韦金华. 母乳喂养对妊娠期糖尿病妇女产后代谢及胰岛功能影响的研究进展[J]. 中国妇幼卫生杂志, 2022, 13(3): 75-78. |
| [38] | 高泓, 谢春光, 郭宝根, 等. 从伏邪理论对糖尿病大血管病变代谢记忆的理论探讨[J]. 时珍国医国药, 2013, 24(9): 2203-2204. |
| [39] | Lipska, K.J. and Laiteerapong, N. (2019) Lack of Glycemic Legacy Effects in the Veterans Affairs Diabetes Trial. New England Journal of Medicine, 380, 2266-2267. https://doi.org/10.1056/NEJMe1905495 |
| [40] | 谢红艳, 李天浩, 高泓, 等. 以健脾升阳法探讨糖尿病血管病变的防治[J]. 成都中医药大学学报, 2018, 41(2): 89-90+96. |
| [41] | 高泓, 段玉红, 富晓旭, 等. 中药参芪复方在抑制代谢记忆保护糖尿病大血管中的作用评析[J]. 辽宁中医杂志, 2019, 46(8): 1780-1783. |
| [42] | 张愿, 谢红艳, 鄢然, 谢春光, 参芪复方加味治疗脾虚型2型糖尿病及防治糖尿病大血管病变的临床观察[J]. 中华中医药学刊, 2019, 37(9): 2125-2127. |
