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镉和汞对毛蚶心脏组织影响
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Abstract:
健康的心脏机能对动物的健康甚至生存至关重要，虽然目前研究主要集中在脊椎动物，但关于双壳类软体动物心脏的毒性影响，尚存认知空白。为探究Cd2+、Hg2+对毛蚶心脏组织结构的影响，通过设定不同浓度、时间及金属的单一或联合暴露，构建了对照组与实验组，实验周期为48小时。应用组织学方法本研究详细观察了Cd2+和Hg2+对毛蚶心脏组织结构的影响。研究结果显示，Cd2+和Hg2+可引起毛蚶心肌损伤，如心肌纤维断裂、细胞水肿或坏死，细胞间隙增大；以及纤维排列紊乱和纤维化等病理现象。随重金属浓度增加，病理程度加重。此外，两种金属对毛蚶生理的毒性作用呈现出拮抗关系。本研究为理解重金属对毛蚶的毒性机制提供了重要基础。
Healthy heart function is crucial to the health and even survival of animals. Although the current research mainly focuses on vertebrates, there is still a cognitive gap about the toxic effects of bivalve mollusks on the heart. In order to explore the effects of Cd2+ and Hg2+ on the cardiac tissue structure of Scapharca subcrenata, the control group and the experimental group were constructed by setting different concentrations, time and single or combined exposure of metals. The experimental period was 48 hours. The effects of Cd2+ and Hg2+ on the cardiac structure of Scapharca subcrenata were observed in detail by histological method. The results showed that Cd2+ and Hg2+ could cause myocardial injury in Scapharca subcrenata, including myocardial fiber breakage, cell edema or necrosis, and pathological phenomena such as fiber arrangement disorder and fibrosis. With the increase of heavy metal concentration, the pathological degree was serious. In addition, the toxic effects of the two metals on the physiology of Scapharca subcrenata showed an antagonistic relationship. This study provides an important basis for understanding the toxic mechanism of heavy metals on Scapharca subcrenata.
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