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肿瘤标志物、免疫组化、炎症指标对结直肠腺癌的影响
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Abstract:
结直肠癌作为一类临床上常见的消化道恶性肿瘤,其具体的发病机理比较复杂。该病在病情初期的症状并无典型表现,所以入院就诊并接受相关治疗的时候,病情已经出现了显著性的恶化。对于人体内肿瘤的存在状态、生长状况以及活性表现等关键信息,可以通过肿瘤标志物获得科学且有效的反映。因此,肿瘤标志物也被大众认为是最有价值的早期发现肿瘤的检测工具之一。免疫组织化学(IHC)技术则能够通过针对性地寻找和识别细胞以及组织内的抗原,以初步判断肿瘤的性质,进而实现更为精确的疾病分期,以及挖掘肿瘤出现的起因等等。另外,炎症细胞在某种程度上可能会通过诱发细胞的增殖活动,进一步推助癌症在体内的发生和发展。近年来大量关于结直肠癌预后的研究,这篇综述将总结目前的研究进展,以便更好地了解肿瘤标志物、免疫组化、炎症指标对结直肠腺癌的影响,为进一步评估结直肠腺癌预后情况提供思路。
Colorectal cancer, as a common type of digestive tract malignant tumor in clinical practice, has a complex specific pathogenesis. The initial symptoms of this disease do not have typical manifestations, so by the time of admission and receiving relevant treatment, the condition had significantly deteriorated. Key information such as the presence, growth, and activity of tumors in the human body can be scientifically and effectively reflected through tumor markers. Therefore, tumor markers are also widely regarded as one of the most valuable early detection tools for tumors. Immunohistochemistry (IHC) technology can identify and identify antigens in cells and tissues in a targeted manner to preliminarily determine the nature of tumors, thereby achieving more accurate disease staging and uncovering the causes of tumor occurrence. In addition, inflammatory cells may to some extent promote the occurrence and development of cancer in the body by inducing cell proliferation activity. In recent years, there has been a large amount of research on the prognosis of colorectal cancer. This review will summarize the current research progress in order to better understand the impact of tumor markers, immunohistochemistry, and inflammatory indicators on colorectal adenocarcinoma, and provide ideas for further evaluating the prognosis of colorectal adenocarcinoma.
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