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肺结节研究进展
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Abstract:
肺结节的治疗痛点在于其良恶性难以鉴别、随访周期长且容易演变为肺癌，以及现有治疗手段的局限性。西医学对于肺结节早期干预及其恶变后的处理缺少对应的治疗，在早期多以随访管理为主，无针对性有效药物。因此，如何有效地早期干预肺结节的进展，成为临床工作中的一大难题。本文旨在综述肺结节的流行病学、定义和分类、肺结节评估及恶性风险预测模型，肺结节的随访管理及目前针对肺结节的中西医干预措施。通过归纳整理这些信息，可以为未来的肺结节进一步研究和临床工作提供必要的参考和指导。
The pain points in the treatment of pulmonary nodules lie in the difficulty in distinguishing between benign and malignant, the long follow-up period, and the tendency to evolve into lung cancer, as well as the limitations of existing treatment methods. Western medicine lacks corresponding treatment for early intervention and management of malignant transformation of pulmonary nodules, and in the early stages, follow-up management is mainly used without targeted and effective drugs. Therefore, how to effectively intervene in the progression of pulmonary nodules in the early stage has become a major challenge in clinical work. This article aims to review the epidemiology, definition and classification of pulmonary nodules, pulmonary nodule assessment and malignant risk prediction models, follow-up management of pulmonary nodules, and current Chinese and Western medicine interventions for pulmonary nodules. By summarizing and organizing this information, it can provide necessary reference and guidance for further research and clinical work on pulmonary nodules in the future.
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