The 5E teaching mode is a modern education mode based on the constructivism teaching theory, including “attraction”, “inquiry”, “interpretation”, “transfer” and “evaluation” five steps, emphasizing the subject status of students in the classroom, the leading role of teachers, and the implementation of the constructivism teaching concept. As a key concept emerging in the field of education in recent years, scientific core literacy has put forward higher requirements for students’ comprehensive development, focusing on practice and comprehensive application, emphasizing the promotion of scientific thinking and the cultivation of innovative consciousness. In practice, the 5E teaching mode has obvious commonality with the scientific core literacy of junior middle school. Therefore, the organic combination of science core literacy and 5E teaching mode, and the creation of reasonable learning scenarios in junior high school science teaching practice to apply, can fit the law of students’ cognitive development, and then effectively train and develop students’ scientific spirit and inquiry ability, and promote the formation of good science core literacy.
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