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慢加急性肝衰竭的预后评估模型及治疗研究现状
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Abstract:
慢加急性肝衰竭(Acute-on-chronic liver failure, ACLF)是指在慢性肝病基础上，由于各种诱因引起的以急性肝功能损伤、凝血功能障碍为主要表现的一组临床症候群。该病起病急、进展快、预后差、短期病死率高，因此早期对ACLF患者进行准确的预后评估及治疗十分重要。本文主要就慢加急性肝衰竭的预后评估模型及治疗进展进行综述，旨在能为指导临床医疗、提高患者生存质量提供帮助。
Acute-on-chronic liver failure (ACLF) refers to a group of clinical symptoms caused by acute liver function injury and coagulopathy on the basis of chronic liver disease. The disease has rapid onset, rapid progression, poor prognosis and high short-term mortality. Therefore, it is very important to carry out accurate prognosis assessment and treatment for ACLF patients in the early stage. This article mainly reviews the prognostic evaluation model and treatment progress of chronic acute liver failure, aiming to provide help for guiding clinical treatment, improving the quality of life of patients and rationally allocating medical resources.
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