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感染性角膜炎的病原学诊断
Etiological Diagnosis of Infectious Keratitis

DOI: 10.12677/acm.2024.1441281, PP. 2191-2195

Keywords: 感染性角膜炎,实验室培养,活体共聚焦显微镜,下一代测序技术
Infectious Keratitis
, Laboratory Culture, In Vivo Confocal Microscopy, Next-Generation Sequencing

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Abstract:

在世界范围内,尤其是发展中国家,感染性角膜炎是主要的致盲性眼病,其地位仅次于白内障。目前,诊断感染性角膜炎的金标准仍是微生物培养以及刮片检查,但是其阳性率较低、耗时较长。对于眼科医生来说,感染性角膜炎的诊断、治疗和预防方面仍然面临巨大挑战。因此,开发快速且敏感的感染性角膜炎的诊断方法至关重要。本文对近年来各种检测感染性角膜炎的诊断技术的研究现状进行综述,并讨论各种诊断技术在角膜炎病原学诊断中存在的问题和应用前景。
Infectious keratitis is the leading cause of blindness worldwide, especially in developing countries, second only to cataracts. At present, the gold standard for the diagnosis of infectious keratitis is still microbial culture and scraping, but it has the characteristics of low positive rate and long time consuming. For ophthalmologists, the diagnosis, treatment and prevention of infectious keratitis still face great challenges. Therefore, it is very important to develop a rapid and sensitive diagnostic method for infectious keratitis. This article reviews the research status of various diagnostic techniques for the detection of infectious keratitis in recent years, and discusses the problems and application prospects of various diagnostic techniques in the etiological diagnosis of keratitis.

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